搜索页_ APD at 30% repolarization

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在“Elsevier电子期刊”中，命中：59条，耗时：0.0719625 秒

在所有数据库中总计命中：70条

1.Significance of integrated in silico transmural ventricular wedge preparation models of human non-failing and failing hearts for safety evaluation of drug candidates

作者：Taeko Kubo ; DVM ; PhD^a ; ^b ; ^c ; ^{taeko-kubo@ds-pharma.co.jp} ; ^{taekok2016@gmail.com} ; Takashi Ashihara ; MD ; PhD^b ; Tadashi Tsubouchi ; PhD^a ; Minoru Horie ; MD ; PhD^b

关键词：AP ; action potential ; APD ; action potential duration ; APD30 ; APD at 30% repolarization ; APD90 ; APD at 90% repolarization ; APD30&ndash ; 90 ; APD90&ndash ; APD30 ; [Ca2 ; +]i ; intracellular Ca2 ; + concentration ; CiPA ; Comprehensive in vitro Proarrhythmia Assay ; CV ; conduction velocity ; EAD ; early afterdepolarization ; ECG ; electrocardiogram ; Endo ; endocardial ; Epi ; epicardial ; FH ; failing heart ; ICH ; International Conference of Harmonization ; IQ-CSRC ; Innovation and Quality in Pharmaceutical Deve

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2017

2.The positive frequency-dependent electrophysiological effects of the I_Kur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation

作者：John Ford ; PhD^* ; James Milnes ; PhD^* ; Said El Haou ; PhD^* ; Erich Wettwer ; PhD^&dagger ; ; Simone Loose ; MD^&dagger ; ; Klaus Matschke ; MD^&Dagger ; ; Benoit Tyl ; MD^§ ; ; Patrick Round ; MBBS^* ; Ursula Ravens ; MD^&dagger ; ; ^{ravens@rcs.urz.tu-dresden.de" class="auth_mail" title="E-mail the corresponding author}

关键词：AF ; atrial fibrillation ; ANOVA ; analysis of variance ; AP ; action potential ; APA ; action potential amplitude ; APD20 ; APD50 ; APD90 ; action potential duration at 20% ; 50% ; and 90% of repolarization ; cAF ; chronic atrial fibrillation ; DMSO ; dimethyl sulfoxide ; dV/dtmax ; maximum upstroke velocity ; ECG ; electrocardiogram/electrocardiographic ; ERP ; effective refractory period ; HR ; heart rate ; IKur ; ultra-rapidly activating delayed-rectifier potassium current ; pAF ; paroxysmal atrial fibrillation ; PLT20

刊名：Heart Rhythm

出版年：2016

3.Unmasking atrial repolarization to assess alternans, spatiotemporal heterogeneity, and susceptibility to atrial fibrillation

作者：Richard L. Verrier ; PhD ; FHRS^* ; ^&dagger ; ; ^{rverrier@bidmc.harvard.edu" class="auth_mail" title="E-mail the corresponding author} ; Henrique Fuller ; BS^* ; ^&Dagger ; ; Fernanda Justo ; BS^* ; ^&Dagger ; ; Bruce D. Nearing ; PhD^* ; ^&dagger ; ; Sridharan Rajamani ; PhD^§ ; ; Luiz Belardinelli ; MD^§ ;

关键词：AF ; atrial fibrillation ; APB ; atrial premature beat ; APD ; action potential duration ; LCx ; left circumflex ; MAP ; monophasic action potential ; MMA ; modified moving average ; PTa ; atrial PT interval ; STa ; Atrial ST segment ; Ta ; atrial T (repolarization) wave ; TWAa ; atrial T-wave alternans ; TWHa ; atrial T-wave heterogeneity ; VNS ; vagus nerve stimulation

刊名：Heart Rhythm

出版年：2016

4.Divergent electrophysiologic profile of fluconazole and voriconazole in an experimental whole-heart model of proarrhythmia

作者：Gerrit Frommeyer^a ; ^{gerrit.frommeyer@ukmuenster.de" class="auth_mail" title="E-mail the corresponding author} ; Christina Fischer^a ; Philipp S. Lange^a ; Patrick Leitz^a ; Michael Fehr^b ; Harilaos Bogossian^c ; Peter Milberg^a ; Lars Eckardt^a

关键词：Fluconazole ; Voriconazole ; Dispersion of repolarization ; Proarrhythmia ; Sudden cardiac death

刊名：European Journal of Pharmacology

出版年：2016

5.Low proarrhythmic potential of citalopram and escitalopram in contrast to haloperidol in an experimental whole-heart model

作者：Gerrit Frommeyer^a ; ^{gerrit.frommeyer@ukmuenster.de" class="auth_mail" title="E-mail the corresponding author} ; Benedict Brü ; cher^a ; Henning von der Ahe^a ; Sven Kaese^a ; Dirk G. Dechering^a ; Simon Kochhä ; user^a ; Harilaos Bogossian^b ; Peter Milberg^a ; Lars Eckardt^a

关键词：Citalopram ; Escitalopram ; Haloperidol ; Dispersion of repolarization ; Proarrhythmia ; Sudden cardiac death

刊名：European Journal of Pharmacology

出版年：2016

6.Reduced response to I_Kr blockade and altered hERG1a/1b stoichiometry in human heart failure

作者：Katherine M. Holzem^a ; Juan F. Gomez^b ; Alexey V. Glukhov^a ; Eli J. Madden^a ; Aaron C. Koppel^a ; Gregory A. Ewald^a ; Beatriz Trenor^b ; Igor R. Efimov^a ; ^c ; ^{igor@wustl.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AP ; action potential ; APD ; action potential duration ; APD80 ; action potential duration at 80% repolarization ; D ; donor ; Endo ; endocardium ; Epi ; epicardium ; HF ; heart failure ; F ; failing ; LV ; left ventricle ; Mid ; midmyocardium

刊名：Journal of Molecular and Cellular Cardiology

出版年：2016

7.There and back again: Iterating between population-based modeling and experiments reveals surprising regulation of calcium transients in rat cardiac myocytes

作者：Ryan A. Devenyi ; Eric A. Sobie ; ^{eric.sobie@mssm.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AP ; action potential ; APD50 ; action potential duration at 50% repolarization ; CaT ; Ca2 ; + transient ; CaTA ; Ca2 ; + transient amplitude ; LV ; left ventricle ; Ito ; transient outward current ; IKur ; ultra-rapidly rectifying current ; ICaL ; L-type Ca2 ; + current ; SERCA ; sarco/endoplasmic reticulum Ca2 ; + ATPase ; NCX ; Na+/Ca2 ; + exchanger ; PMCA ; plasma membrane Ca2 ; + ATPase ; NKA ; Na+/K+ ATPase ; RyR ; ryanodine receptor ; Kdecay ; decay rate of CaT ; Kdecay ; caff ; CaT decay rate in pre

刊名：Journal of Molecular and Cellular Cardiology

出版年：2016

8.Human ex-vivo action potential model for pro-arrhythmia risk assessment

作者：Guy Page^a ; Phachareeya Ratchada^a ; Yannick Miron^a ; Guido Steiner^b ; Andre Ghetti^a ; Paul E. Miller^a ; Jack A. Reynolds^a ; Ken Wang^b ; Andrea Greiter-Wilke^b ; Liudmila Polonchuk^b ; Martin Traebert^c ; Gary A. Gintant^d ; Najah Abi-Gerges^a ; ^{Najah.abigerges@anabios.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Human heart ; Ventricular trabeculae ; Action potential ; Pro-arrhythmia assessment ; Drug discovery and development

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

9.Atrial-selective targeting of arrhythmogenic phase-3 early afterdepolarizations in human myocytes

作者：Stefano Morotti^a ; Andrew D. McCulloch^b ; Donald M. Bers^a ; Andrew G. Edwards^c ; ^d ; Eleonora Grandi^a ; ^{ele.grandi@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ACh ; acetylcholine ; AF ; atrial fibrillation ; AP ; action potential ; APD ; action potential duration ; [Ca2 ; +]i ; intracellular Ca2 ; + concentration ; CaMKII ; Ca2 ; +/calmodulin-dependent protein kinase II ; DAD ; delayed afterdepolarization ; EAD ; early afterdepolarization ; Em ; membrane potential ; ICa ; L-type Ca2 ; + current ; INa ; Na+ current ; IKr ; delayed rectifier K+ current ; INCX ; Na+/Ca2 ; + exchanger current ; ISO ; isoproterenol ; NCX ; Na+/Ca2 ; + exchanger ; pAF ; paroxysmal atria

刊名：Journal of Molecular and Cellular Cardiology

出版年：2016

10.0173 : Mechanisms behind the pro-arrhythmogenic state induced by exposure to chronic intermittent hypoxia

作者：Jessica Morand ; ^{jessica.k.morand@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Claire Arnaud ; Jean-Louis Pé ; pin ; Diane Godin-Ribuot

刊名：Archives of Cardiovascular Diseases Supplements

出版年：2016

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