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在“Elsevier电子期刊”中，命中：1,169条，耗时：0.0719705 秒

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1.Maturation and processing of the amyloid precursor protein is regulated by the potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2)

作者：Susanne Frykman^a ; ^{susanne.frykman@ki.se} ; Mitsuhiro Inoue^a ; ^b ; Atsushi Ikeda^b ; Yasuhiro Teranishi^a ; ^b ; Takahiro Kihara^a ; ^b ; Jolanta L. Lundgren^a ; Natsuko G. Yamamoto^a ; ^b ; Nenad Bogdanovic^a ; Bengt Winblad^a ; Sophia Schedin-Weiss^a ; Lars O. Tjernberg^a

关键词：Amyloid precursor protein ; Amyloid beta-peptide ; Alzheimer disease ; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 ; Glycosylation

刊名：Biochemical and Biophysical Research Communications

出版年：2017

2.Metabotropic glutamate receptors and neurodegenerative diseases

作者：Fabiola M. Ribeiro^a ; Luciene B. Vieira^b ; Rita G.W. Pires^c ; Roenick P. Olmo^a ; Stephen S.G. Ferguson^d ; ^{sferguso@uottawa.ca}

关键词：AMPA ; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid ; Aβ ; amyloid β peptide ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; BDNF ; brain derived neurotrophic factor ; BF ; basal forebrain ; CGA ; chromogranin A ; CNS ; central nervous system ; DAG ; diacylghycerol ; ERK ; extracellular signal-regulated kinase ; GABA ; gamma-aminobutyric acid ; GDNF ; glial cell line-derived neurotrophic factor ; GIRK ; inward rectifying K+ channels ; GP ; globus pallidum ; GPe ; globus pallidum externa ; GPCR ; G

刊名：Pharmacological Research

出版年：2017

3.The pertussis hypothesis: Bordetella pertussis colonization in the pathogenesis of Alzheimer’s disease

作者：Keith Rubin ; MD ^{keith@iliadbio.com} ; Steven Glazer ; MD ; ^{glazer@iliadbio.com}

关键词：AD ; Alzheimer&rsquo ; s disease ; BP ; Bordetella pertussis ; CNS ; central nervous system ; Aβ ; amyloid β ; NFT ; neurofibrillary tangle ; APOE ; apolipoprotein E ; HSV-1 ; herpes simplex virus-1 ; AβPP ; Aβ precursor protein ; BACE-1 ; β-site amyloid precursor protein-cleaving enzyme ; US ; United States ; wPV ; whole cell pertussis vaccine ; aPV ; acellular pertussis vaccine ; SCBPC ; subclinical Bordetella pertussis colonization ; DPT ; diphtheria pertussis and tetanus vaccine ; PCR ; polymerase chain reaction ; CDC ; Cen

刊名：Immunobiology

出版年：2017

4.Copper brain protein protection against free radical-induced neuronal death: Survival ratio in SH-SY5Y neuroblastoma cell cultures

作者：Roger Deloncle^a ; ^{roger.deloncle@univ-tours.fr} ; Bernard Fauconneau^b ; Olivier Guillard^c ; ¹ ; José ; Delaval^d ; Gé ; rard Lesage^e ; Alain Pineau^f ; ¹

关键词：Copper ; Manganese ; Free radicals ; SH-SY5Y cells ; Neuronal death ; Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

刊名：Journal of Trace Elements in Medicine and Biology

出版年：2017

5.High fat diet induces brain insulin resistance and cognitive impairment in mice

作者：Vishal Kothari^a ; Yuwen Luo^a ; Talia Tornabene^a ; Ann Marie O'Neill^b ; Michael W Greene^a ; Thangiah Geetha^c ; Jeganathan Ramesh Babu^a ; ^{jeganrb@auburn.edu}

关键词：AD ; Alzheimer disease ; APP ; amyloid precursor protein ; CREB ; CAMP-response element binding ; GFAP ; Glial Fibrillary Acidic Protein ; GTT ; glucose tolerance test ; HFD ; high fat diet ; HFS ; high fat diet with sugar ; HOMA ; homeostatic model assessment ; IDE ; insulin degrading enzyme ; IR ; insulin resistance ; ITT ; insulin tolerance test ; PSD ; postsynaptic density ; RQ ; respiratory exchange quotient ; SEM ; standard error of the mean ; T2DM ; type 2 diabetes

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

6.Formononetin attenuates Aβ_25-35-induced cytotoxicity in HT22 cells via PI3K/Akt signaling and non-amyloidogenic cleavage of APP

作者：Lizhi Chen ; Shanshan Ou ; Lingqi Zhou ; Hai Tang ; Jie Xu ; ^{xujie@mail.sysu.edu.cn} ; Kaihua Guo ; ^{guokh@mail.sysu.edu.cn}

关键词：amyloid β ; Aβ ; Alzheimer&rsquo ; s disease ; AD ; estrogen receptor α ; ERα ; formononetin ; Form ; soluble amyloid precursor protein α ; sAPPα

刊名：Neuroscience Letters

出版年：2017

7.Neurophysiological assessment of neural network plasticity and connectivity: Progress towards early functional biomarkers for disease interception therapies in Alzheimer’s disease

作者：C. Walsh ; W.H.I.M. Drinkenburg ; A. Ahnaou ; ^{aahnaou@its.jnj.com}

关键词：Aβ ; amyloid Beta ; ACh ; acetylcholine ; AChEI ; acetylcholinesterase inhibitor ; ACH ; amyloid cascade hypothesis ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; ARIA-E ; amyloid related imaging abnormalities related to edema ; CSF ; cerebrospinal fluid ; EEG ; electroencephalogram/electroencephalography ; EROS ; event-related oscillations ; ERP ; event-related potentials ; fAD ; familial Alzheimer&rsquo ; s disease ; fMRI ; functional MRI ; FTDP-17 ; frontotemporal dementia and parkinsonism linked to

刊名：Neuroscience & Biobehavioral Reviews

出版年：2017

8.The σ1 receptor regulates accumulation of GM1 ganglioside-enriched autophagosomes in astrocytes

作者：Rika Kasahara^a ; Naoki Yamamoto^a ; ^b ; ^{na-yamam@hokuriku-u.ac.jp} ; Kenji Suzuki^c ; Kazuya Sobue^d

关键词：σ1R ; sigma (σ)-1 receptor ; Aβ ; amyloid β-protein ; AD ; alzheimer disease ; APP ; amyloid precursor protein ; CTX-HRP ; Horseradish peroxidase-cholera toxin B subunit ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; DR ; dopamine receptor ; DRMs ; detergent-resistant membrane microdomains ; ERK ; extracellular signal-regulated kinase ; FBS ; fetal bovine serum ; GM1 ; GM1 ganglioside ; PBS ; phosphate-buffered saline ; PDMP ; (± ; )-threo-1-phenyl-2-decanoylamine-3-morpholino-1-propanol hydrochloride ; PF

刊名：Neuroscience

出版年：2017

9.Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer’s disease, a case report

作者：Claudio D&rsquo ; Addario^a ; ^b ; ^{cdaddario@unite.it} ; Sussy Bastias Candia^c ; Beatrice Arosio^d ; ^e ; Martina Di Bartolomeo^a ; Carlo Abbate^e ; Alessandra Casè ; ^d ; Sanzio Candeletti^f ; Patrizia Romualdi^f ; Sarah Damanti^e ; ^g ; Mauro Maccarrone^b ; ^h ; ¹ ; Luigi Bergamaschini^d ; ⁱ ; ¹ ; Daniela Mari^d ; ^e ; ¹

关键词：AD ; Alzheimer&rsquo ; s Disease ; HADACs ; histone deacetylases ; APP ; amyloid precursor protein ; SIRT1 ; sirtuin 1 ; APOE ; apolipoprotein E ; PSEN1 ; presenilin 1 ; PIN1 ; peptidyl prolyl isomerase 1 ; PBMCs ; peripheral blood mononuclear cells ; DNMTs ; DNA methyltransferases ; Aβ ; Amyloid-β ; Ptau ; Phosphorylated tau ; CSF ; cerebrospinal fluid ; MCI ; Mild Cognitive Impairment ; H3K27me3 ; Histone 3 lysine 27 trimethylated ; H3K4me3 ; Histone 3 lysine 4 trimethylated ; H3K9Ac ; Histone 3 lysine 9 acetylated

刊名：Journal of the Neurological Sciences

出版年：2017

10.Liraglutide prevents cognitive decline in a rat model of streptozotocin-induced diabetes independently from its peripheral metabolic effects

作者：Caterina Palleria^a ; Antonio Leo^a ; Francesco Andreozzi^b ; Rita Citraro^a ; Michelangelo Iannone^c ; Rosangela Spiga^b ; Giorgio Sesti^b ; Andrew Constanti^d ; Giovambattista De Sarro^a ; Franco Arturi^b ; Emilio Russo^a ; ^{erusso@unicz.it}

关键词：AD ; Alzheimer&rsquo ; s disease ; APP/PS1 ; amyloid precursor protein/presenilin 1 ; Aβ ; β-amyloid ; CNS ; central nervous system ; CTRL ; control ; EPM ; elevated plus maze ; FST ; forced swimming test ; GLP-1R ; glucagon-like peptide-1 receptor ; i.c.v. ; intracerebroventricular ; i.p. ; intraperitoneally ; IL ; initial latency ; IT ; immobility time ; LIR ; liraglutide ; mTOR ; mammalian target of rapamycin ; MWM ; Morris water maze ; NOS ; nitric oxide synthase ; OF ; open field arena ; p70S6 K ; p70 ; ribosomal protein S6 kina

刊名：Behavioural Brain Research

出版年：2017

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