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在“Elsevier电子期刊”中，命中：603条，耗时：0.0979532 秒

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1.Drug development for refractory epilepsy: The past 25 years and beyond

作者：Ambica Golyala^a ; Patrick Kwan^a ; ^b ; ^{patrick.kwan@unimelb.edu.au}

关键词：Antiepileptic drugs ; Epilepsy ; Clinical trials ; Animal models ; Pharmacoresistance ; Precision medicine

刊名：Seizure

出版年：2017

2.Fetal antiepileptic drug exposure and cognitive outcomes

作者：Rebecca L. Bromley^a ; ^b ; ^{Rebecca.bromley@manchester.ac.uk} ; ^{rebecca.bromley@cmft.nhs.uk} ; Gus A. Baker^c

关键词：Epilepsy ; Pregnancy ; In utero ; Antiepileptic drugs ; Neurodevelopment

刊名：Seizure

出版年：2017

3.Challenges in the clinical development of new antiepileptic drugs

作者：Valentina Franco^a ; ^{valentina.franco@mondino.it" class="auth_mail" title="E-mail the corresponding author} ; Jacqueline A. French^b ; Emilio Perucca^a ; ^c

关键词：Epilepsy ; Antiepileptic drugs ; Drug development ; Clinical trials

刊名：Pharmacological Research

出版年：2016

4.Antiepileptic drugs in development pipeline: A recent update

作者：Harjeet Kaur ; Baldeep Kumar ; Bikash Medhi ; ^{drbikashus@yahoo.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Seizures ; Epilepsy ; Drug development ; Neuroprotection ; Clinical trial ; Antiepileptic

刊名：eNeurologicalSci

出版年：2016

5.Efficacy of antiepileptic drugs for the treatment of Dravet syndrome with different genotypes

作者：Xiu-Yu Shi^a ; ^b ; ^c ; Yuko Tomonoh^a ; ^b ; Wen-Ze Wang^a ; ^b ; ^d ; Atsushi Ishii^a ; ^b ; Norimichi Higurashi^a ; ^b ; ^e ; Hirokazu Kurahashi^f ; Sunao Kaneko^g ; Shinichi Hirose^a ; ^b ; ^{hirose@fukuoka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; The Epilepsy Genetic Study Group ; Japan (Chairperson ; SK)

关键词：Genetic tests ; Dravet syndrome ; Antiepileptic drug therapy ; Efficacy

刊名：Brain and Development

出版年：2016

6.Functionalized nanocarrier combined seizure-specific vector with P-glycoprotein modulation property for antiepileptic drug delivery

作者：Jiansheng Liu^a ; ^e ; ¹ ; Yajing He^b ; ¹ ; Jun Zhang^c ; Jiajia Li^b ; Xiangrong Yu^c ; Zhonglian Cao^d ; Fanmin Meng^b ; Yuwu Zhao^e ; Xunyi Wu^a ; ^{mythstory@126.com" class="auth_mail" title="E-mail the corresponding author} ; Teng Shen^b ; ^{shenteng@fudan.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Zhen Hong^a

关键词：Epilepsy ; Antiepileptic drug ; Lamotrigine ; Polymeric micelles ; Tryptophan ; P-glycoprotein

刊名：Biomaterials

出版年：2016

7.Bone Mineral Changes in Epilepsy Patients During Initial Years of Antiepileptic Drug Therapy

作者：Baemisla Shiek Ahmad¹ ; ² ; Terence John O'Brien¹ ; Alexandra Gorelik¹ ; ³ ; Keith David Hill⁴ ; John Dennis Wark ; ¹ ; ⁵ ; ^{jdwark@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Antiepileptic drugs ; bone mineral density ; dual-energy X-ray absorptiometry (DXA) ; epilepsy/seizures ; longitudinal study

刊名：Journal of Clinical Densitometry

出版年：2016

8.Upholding WAG/Rij rats as a model of absence epileptogenesis: Hidden mechanisms and a new theory on seizure development

作者：Emilio Russo^a ; ^{erusso@unicz.it} (Prof.) ; Rita Citraro^a ; Andrew Constanti^b ; Antonio Leo^a ; Annika Lü ; ttjohann^c ; ^d ; Gilles van Luijtelaar^c ; Giovambattista De Sarro^a

关键词：Epileptogenesis ; Spontaneous chronic absence seizures ; Genetic animal model ; Antiepileptic drugs ; WAG/Rij rats

刊名：Neuroscience & Biobehavioral Reviews

出版年：2016

9.The importance of triazole scaffold in the development of anticonvulsant agents

作者：Adile Ayati^a ; Saeed Emami^b ; ^{sd_emami@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Alireza Foroumadi^a ; ^{aforoumadi@yahoo.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Anticonvulsant agents ; Antiepileptic drugs ; Epilepsy ; 12 ; 4-Triazole ; Fused triazoles

刊名：European Journal of Medicinal Chemistry

出版年：2016

10.Characterization of Disopyramide derivative ADD424042 as a non-cardiotoxic neuronal sodium channel blocker with broad-spectrum anticonvulsant activity in rodent seizure models

作者：Marek Kró ; l^a ; Marcin Ufnal^b ; Bartłomiej Szulczyk^a ; ^c ; Piotr Podsadni^a ; Adrian Drapała^b ; Jadwiga Turło^a ; Maciej Dawidowski^a ; ^{maciej.dawidowski@wum.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：AAD ; antiarrhythmic drug ; ABP ; arterial blood pressure ; ADD ; anticonvulsant drug development program ; ADD424042 ; 2-(2-chlorophenyl)-2-(pyridin-2-yl)acetamide ; AED ; antiepileptic drug ; AGS ; audiogenic seizure-susceptible mice ; AP ; action potential ; ASP ; anticonvulsant Screening Program ; CKM ; corneally kindled mice model ; DISO ; Disopyramide phosphate ; ECG ; electrocardiogram ; HC ; hippocampus ; HERG ; Human ether-a-go-go-related Gene ; HR ; heart rate ; ivMET ; intravenous infusion of Metrazol model ; KA

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

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