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在“Elsevier电子期刊”中，命中：20条，耗时：0.1009565 秒

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1.Concentration-response relationship of the 伪7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays

关键词：ACh ; acetylcholine ; aCSF ; artificial cerebrospinal fluid ; AP ; anterior posterior ; AP5 ; (2R)-amino-5-phosphonopentanoate ; AUC ; area under the concentration-time curve ; CHO ; Chinese hamster ovary ; Cmax ; maximum concentration ; Cu ; brain ; unbound brain concentration ; DMSO ; dimethyl sulfoxide ; EEG ; electroencephalogram ; EVP-6124 (encenicline) ; (R)-7-chloro-N-quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide ; fEPSP ; field excitatory postsynaptic potential ; FRM-17874 ; (R)-7-fluoro-N-quinuclidin-3-yl)benz

刊名：Biochemical Pharmacology

出版年：2015

2.A multi-route model of nicotine-cotinine pharmacokinetics, pharmacodynamics and brain nicotinic acetylcholine receptor binding in humans

作者：Justin G. Teeguarden^a ; ¹ ; ^{justin.teeguarden@pnl.gov} ; ^{Justin.Teeguarden@pnnl.gov} ; Conrad J. Housand^b ; ¹ ; Jordan N. Smith^a ; Paul M. Hinderliter^a ; Rudy Gunawan^c ; Charles A. Timchalk^a

关键词：AUC ; area under the curve ; BW ; body weight ; Cant50 ; tolerance &ldquo ; concentration&rdquo ; CLKC ; nicotine renal clearance ; CLMC ; nicotine metabolic clearance ; COTCL ; total cotinine clearance (unscaled) ; COTCLC ; total cotinine clearance (scaled) ; CVVB ; blo

刊名：Regulatory Toxicology and Pharmacology

出版年：2013

3.Mecamylamine-precipitated nicotine withdrawal syndrome and its prevention with baclofen: An autoradiographic study of ¦Á₄¦Â₂ nicotinic acetylcholine receptors in mice

作者：André ; s P. Varani^a ; Marta C. Antonelli^b ; Graciela N. Balerio^a ; ^c ; ^{gbalerio@ffyb.uba.ar}

关键词：NIC ; nicotine ; BAC ; baclofen ; MEC ; mecamylamine ; SAL ; saline ; nAChRs ; nicotinic acetylcholine receptors ; Acb ; nucleus accumbens ; Cx ; motor cortex ; CPu ; caudate putamen ; BST ; bed nucleus stria terminalis ; MHb ; medial habenula ; DLG ; dorsal lateral geniculat

刊名：Progress in Neuro-Psychopharmacology and Biological Psychiatry

出版年：2013

4.The effects of acute and repeated nicotine doses on spontaneous activity in male and female Sprague Dawley rats: Analysis of brain area epibatidine binding and cotinine levels

作者：Alan L. Pehrson ; Scott D. Philibin ; Daniel Gross ; Susan E. Robinson ; Robert E. Vann ; John A. Rosecrans ; John R. James

关键词：Nicotine ; Baseline activity ; Brain area nAChR binding ; Behavioral sensitization

刊名：Pharmacology Biochemistry and Behavior

出版年：2008

5.Gestational nicotine exposure regulates expression of AMPA and NMDA receptors and their signaling apparatus in developing and adult rat hippocampus

作者：H. Wang^a ; M.I. Dá ; vila-Garcí ; a^b ; W. Yarl^a ; M.C. Gondré ; -Lewis^a ; ^{mgondre-lewis@howard.edu"" rel=""nofollow}

关键词：prenatal nicotine ; developing hippocampus ; AMPAR ; NMDAR ; nAChR ; postsynaptic signaling

刊名：Neuroscience

出版年：2011

6.Structural differences determine the relative selectivity of nicotinic compounds for native α4β2*-, α6β2*-, α3β4*- and α7-nicotine acetylcholine receptors

作者：Sharon R. Grady ; Ryan M. Drenan ; Scott R. Breining ; Daniel Yohannes ; Charles R. Wageman ; Nikolai B. Fedorov ; Sheri McKinney ; Paul Whiteaker ; Merouane Bencherif ; Henry A. Lester ; Michael J. Marks

关键词：TC2429 ; TC2403 ; TC1698 ; TC2242 ; TC6951 ; Varenicline

刊名：Neuropharmacology

出版年：2010

7.β2 and β4 nicotinic acetylcholine receptor expression changes with progressive parkinsonism in non-human primates

作者：Jennifer M. Kulak ; Hong Fan ; Jay S. Schneider

关键词：Macaca fascicularis ; Macaca mulatta ; Macaca nemestrina ; Epibatidine ; A85380

刊名：Neurobiology of Disease

出版年：2007

8.Effects of chronic neonatal nicotine exposure on nicotinic acetylcholine receptor binding, cell death and morphology in hippocampus and cerebellum

作者：L.Z. Huang ; L.C. Abbott ; U.H. Winzer-Serhan

刊名：Neuroscience

出版年：2007

9.A-186253, a specific antagonist of the α4β2 nAChRs: its properties and potential to study brain nicotinic acetylcholine receptors

作者：Itier ; Valé ; rie ; Schö ; nbä ; chler ; Roland ; Tribollet ; Eliane ; Honer ; Michael ; et. al.

关键词：Neuronal nicotinic receptors ; Brain ; Imaging ; Radiolabeling ; Autoradiography ; Electrophysiology

刊名：Neuropharmacology

出版年：2004

10.Effect of repeated nicotine exposure on high-affinity nicotinic acetylcholine receptor density in spontaneously hypertensive rats

作者：Hohnadel ; Elizabeth J. ; Hernandez ; Caterina M. ; Gearhart ; Debra A. ; Terry ; Alvin V.

关键词：Acetylcholine ; Cholinergic ; Autoradiography ; Cognition ; Dementia ; Attention

刊名：Neuroscience Letters

出版年：2005

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