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Elsevier电子期刊(120)

在“Elsevier电子期刊”中，命中：120条，耗时：0.013992 秒

在所有数据库中总计命中：172条

1.Synthesis and application of β-carbolines as novel multi-functional anti-Alzheimer’s disease agents

作者：William Horton^a ; Abha Sood^a ; Swarada Peerannawar^a ; Nandor Kugyela^a ; Aditya Kulkarni^a ; Rekha Tulsan^a ; Chris D. Tran^a ; Jessica Soule^a ; Harry LeVine III^b ; Bé ; la Tö ; rö ; k^a ; Marianna Tö ; rö ; k^a ; ^{marianna.torok@umb.edu}

关键词：Alzheimer&rsquo ; s disease ; Amyloid beta ; Cholinesterase inhibition ; Antioxidant ; β-Carbolines

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Synthesis, anticholinesterase activity and molecular modeling study of novel carbamate-substituted thymol/carvacrol derivatives

作者：Belma Zengin Kurt^a ; Isil Gazioglu^b ; Aydan Dag^a ; Ramin Ekhteiari Salmas^c ; Gü ; lru Kayık^d ; Serdar Durdagi^c ; ^{serdar.durdagi@med.bau.edu.tr} ; Fatih Sonmez^e ; ^{fsonmez@sakarya.edu.tr}

关键词：Thymol ; Carvacrol ; Carbamate ; Alzheimer&rsquo ; s disease ; Molecular docking ; Molecular dynamics (MD) simulations ; MM-PBSA ; Induced fit docking (IFD)

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

3.Indirect Treatment Comparisons of Ibrutinib Versus Physician’s Choice and Idelalisib Plus Ofatumumab in Patients With Previously Treated Chronic Lymphocytic Leukemia

作者：Sonja Sorensen ; MPH¹ ; ^{Sonja.sorensen@evidera.com} ; Mark Wildgust ; PhD² ; Nishan Sengupta ; PhD³ ; Cristina Trambitas ; MBA⁴ ; Joris Diels ; PhD⁵ ; Suzy van Sanden ; PhD⁵ ; Yingxin Xu ; PharmD ; PhD⁶ ; Emily Dorman ; MPH ; MBA¹

关键词：chronic lymphocytic leukemia ; ibrutinib ; idelalisib ; ofatumumab ; indirect treatment comparison

刊名：Clinical Therapeutics

出版年：2017

4.(−)-Epicatechin derivate from Orostachys japonicus as potential inhibitor of the human butyrylcholinesterase

作者：Jang Hoon Kim^a ; ^c ; Sang-Hyun Lee^b ; Hyun Woo Lee^a ; Ya Nan Sun^a ; Won-Hee Jang^a ; Seo-Young Yang^a ; Hae-Dong Jang^b ; Young Ho Kim^a ; ^{yhk@cnu.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：Orostachys japonicus A. berger ; Crassulaceae ; Cholinesterase ; Competitive inhibitor ; Molecular dymanics

刊名：International Journal of Biological Macromolecules

出版年：2016

5.Insights into (S)-rivastigmine inhibition of butyrylcholinesterase (BuChE): Molecular docking and saturation transfer difference NMR (STD-NMR)

作者：Patrí ; cia Bacalhau^a ; ^b ; ¹ ; Amor A. San Juan^c ; ¹ ; Albertino Goth^c ; A. Teresa Caldeira^a ; ^b ; Rosá ; rio Martins^a ; ^b ; Anthony J. Burke^a ; ^c ; ^{ajb@uevora.pt" class="auth_mail" title="E-mail the corresponding author}

关键词：Cholinesterase inhibition ; Pseudo-irreversible inhibition ; Rivastigmine ; Molecular docking ; STD-NMR

刊名：Bioorganic Chemistry

出版年：2016

6.Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer’s disease based on the fusion of donepezil and melatonin

作者：Jin Wang ; Zhi-Min Wang ; Xue-Mei Li ; Fan Li ; Jia-Jia Wu ; Ling-Yi Kong ; ^{cpu_lykong@126.com" class="auth_mail" title="E-mail the corresponding author} ; Xiao-Bing Wang ; ^{xbwang@cpu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：AchE ; Acetylcholinesterase ; BuChE ; Butyrylcholinesterase ; AD ; Alzheimer&rsquo ; s disease ; Aβ ; β-Amyloid ; CAS ; Catalytic anionic site ; PAS ; Peripheral anionic site ; BBB ; Blood&ndash ; brain barrier ; AβOs ; Soluble Aβ oligomers ; CNS ; Central nervous system ; NFTS ; Neurofibrillary tangles ; ChEs ; Cholinesterases ; ChEIs ; Cholinesterase inhibitors ; CDI ; 1 ; 1&prime ; -Carbonyldiimidazole ; ORAC ; Oxygen radical absorbance capacity ; PAMPA ; Parallel artificial membrane permeation assay

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

7.Synthesis and anti-acetylcholinesterase activity of scopoletin derivatives

作者：Nisachon Khunnawutmanotham^a ; Nitirat Chimnoi^b ; Patchreenart Saparpakorn^c ; Supanna Techasakul^a ; ^c ; ^{fscispt@ku.ac.th" class="auth_mail" title="E-mail the corresponding author} ; ^{supanna@cri.or.th" class="auth_mail" title="E-mail the corresponding author}

关键词：Scopoletin ; Pyridinium derivatives ; Acetylcholinesterase inhibitor ; Synthesis

刊名：Bioorganic Chemistry

出版年：2016

8.Design, synthesis and bioactivity of novel phthalimide derivatives as acetylcholinesterase inhibitors

作者：Weijie Si ; Tao Zhang ; Lanxiang Zhang ; Xiangdong Mei ; ^{xdmei@ippcaas.cn" class="auth_mail" title="E-mail the corresponding author} ; Mengya Dong ; Kaixin Zhang ; Jun Ning

关键词：Substructure combination ; Phthalimide derivatives ; Acetylcholinesterase inhibitor ; Structure&ndash ; activity relationship ; Molecular docking

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

9.Design, synthesis and biological evaluation of novel donepezil-coumarin hybrids as multi-target agents for the treatment of Alzheimer’s disease

作者：Sai-Sai Xie^&dagger ; ; Jin-Shuai Lan^&dagger ; ; Xiaobing Wang ; Zhi-Min Wang ; Neng Jiang ; Fan Li ; Jia-Jia Wu ; Jin Wang ; Ling-Yi Kong ; ^{cpu_lykong@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：BOXHJLTYYUXRSS-UHFFFAOYSA-N ; HXYMYZXCUHALCL-UHFFFAOYSA-N ; OLXGWSKUULDSEJ-UHFFFAOYSA-N ; VCCISXVIIKLUNO-UHFFFAOYSA-N ; XATVGNRTOUJFHU-UHFFFAOYSA-N ; LQNPMZWHOLIOEU-UHFFFAOYSA-N ; GKYZWZKQBZYQOH-UHFFFAOYSA-N ; FDDWWWOIEISVTE-UHFFFAOYSA-N ; KOAOVWXOZSDQBP-UHFFFAOYSA-N ; JURRMYXCDPPYMK-UHFFFAOYSA-N ; IPJZSNUPIXZHAU-UHFFFAOYSA-N ; UUZIPHVUUZOBHC-UHFFFAOYSA-N ; QZRBOLHGJBENEV-UHFFFAOYSA-N ; PDEVIVJKZGXTTC-UHFFFAOYSA-N ; HZEOKPNLIUABIQ-UHFFFAOYSA-N

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

10.Avarol derivatives as competitive AChE inhibitors, non hepatotoxic and neuroprotective agents for Alzheimer’s disease

关键词：Avarol ; Thiosalycil-prenyl-hydroquinones (TPHs) ; Alzheimer&rsquo ; s disease ; Anticholinesterasic compounds ; Neuroprotection ; Molecular modeling

刊名：European Journal of Medicinal Chemistry

出版年：2016

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