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Elsevier电子期刊(121)

在“Elsevier电子期刊”中，命中：121条，耗时：0.0139682 秒

在所有数据库中总计命中：176条

1.G₂/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph₃PAu[SC(OR) = NPh], R = Me, Et, and iPr, during zebrafish development

作者：Kah Kooi Ooi^a ; ^b ; Chien Ing Yeo^b ; Theventhiran Mahandaran^c ; Kok Pian Ang^a ; Abdah Md Akim^a ; Yoke-Kqueen Cheah^a ; Hoi-Ling Seng^d ; ^{hoilings@sunway.edu.my} ; Edward R.T. Tiekink^b ; ^{edwardt@sunway.edu.my}

关键词：Annexin V-FITC ; Recombinant annexin V conjugated to fluorescein isothiocyanate ; APAF-1 ; Apoptotic protease activating factor 1 ; ATR ; Ataxia telangiectasia and Rad3-related ; Bax ; Apoptosis regulator ; Bcl-2 ; B-cell lymphoma 2 ; BIRC-5 ; Baculoviral inhibitor of apoptosis repeat-containing 5/ Survivin ; CCNB1 ; Cyclin B1 ; cdc25C ; Cell division cycle 25C ; CDKN1A ; Cyclin-dependent kinase N1A ; CDK2 ; Cyclin-dependent kinase 2 ; CDK4 ; Cyclin-dependent kinase 4 ; CHEK1/Chk1 ; Checkpoint kinase 1 ; CHEK2/Chk2 ; Ch

刊名：Journal of Inorganic Biochemistry

出版年：2017

2.Inhibition of ATR-dependent feedback activation of Chk1 sensitises cancer cells to Chk1 inhibitor monotherapy

作者：Andrew J. Massey ^{a.massey@vernalis.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Chk1 ; ATR ; ATM ; DNA-PK ; Kinase inhibitor ; Replication stress

刊名：Cancer Letters

出版年：2016

3.Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer

作者：Paola Francica ; Daniel M. Aebersold ; Michaela Medová ; ; ^{michaela.medova@dkf.unibe.ch}

关键词：ATIR ; anti-tumor immune response ; ATM ; ataxia telangiectasia mutated ; CDK ; cyclin-dependent kinase ; CGH ; comparative genomic hybridization ; CHK1 ; checkpoint kinase 1 ; CHK2 ; checkpoint kinase 2 ; DDAs ; DNA-damaging agents ; DDR ; DNA damage response ; DSBs ; double-strand breaks ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; EPHA3 ; EPH Receptor A3 ; FGFR ; fibroblast growth factor receptor ; FOXM1 ; Forkhead box protein M1 ; GAS6 ; growth arrest-specific protein 6 ; H3K9me3 ; histone 3

刊名：Biochemical Pharmacology

出版年：2017

4.Chk1 phosphorylated at serine³⁴⁵ is a predictor of early local recurrence and radio-resistance in breast cancer

作者：Nouf Alsubhi^a ; Fiona Middleton^b ; Tarek M.A. Abdel-Fatah^c ; Peter Stephens^b ; Rachel Doherty^a ; Arvind Arora^a ; Paul M. Moseley^c ; Stephen Y.T. Chan^c ; Mohammed A. Aleskandarany^d ; Andrew R. Green^d ; Emad A. Rakha^d ; Ian O. Ellis^d ; Stewart G. Martin^a ; Nicola J. Curtin^b ; ^{nicola.curtin@ncl.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Srinivasan Madhusudan^a ; ^c ; ^{srinivasan.madhusudan@nottingham.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：Breast cancer ; Local recurrence ; Radiotherapy ; Resistance ; p53 ; Chk1 ; ATR inhibitor ; Chk1 inhibitor

刊名：Molecular Oncology

出版年：2016

5.A convergent preparation of the CHK1 inhibitor MK-8776 (SCH 900776)

作者：Marc A. Labroli ; ^{marc.labroli@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Michael P. Dwyer ; ^{michael.dwyer@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Cory Poker ; Kerry M. Keertikar ; Randall Rossman ; Timothy J. Guzi

关键词：Kinase ; CHK1 ; MK-8776 ; Serine/threonine kinase ; Oncology

刊名：Tetrahedron Letters

出版年：2016

6.Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade

作者：Ranjan Preet^a ; ¹ ; Sumit Siddharth^a ; ¹ ; Shakti Ranjan Satapathy^a ; Sarita Das^a ; Anmada Nayak^a ; Dipon Das^a ; Michael D. Wyatt^b ; Chanakya Nath Kundu^a ; ^{cnkundu@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：9-Aminoacridine ; Base-excision repair ; CHK1 ; Breast cancer ; Quinacrine

刊名：Biochemical Pharmacology

出版年：2016

7.Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

作者：Kumar Sanjiv¹ ; Anna Hagenkort¹ ; José ; Manuel Calderó ; n-Montañ ; o¹ ; Tobias Koolmeister¹ ; Philip M. Reaper² ; Oliver Mortusewicz¹ ; Sylvain A. Jacques¹ ; Raoul V. Kuiper³ ; Niklas Schultz¹ ; Martin Scobie¹ ; Peter A. Charlton² ; John R. Pollard² ; Ulrika Warpman Berglund¹ ; Mikael Altun¹ ; Thomas Helleday¹ ; ^{thomas.helleday@scilifelab.se" class="auth_mail" title="E-mail the corresponding author}

关键词：ATR ; CHK1 ; synthetic lethality ; cancer ; DNA damage ; replication stress

刊名：Cell Reports

出版年：2016

8.“Combo” nanomedicine: Co-delivery of multi-modal therapeutics for efficient, targeted, and safe cancer therapy

作者：Jessica A. Kemp^a ; Min Suk Shim^b ; Chan Yeong Heo^a ; ^c ; ^d ; Young Jik Kwon^a ; ^e ; ^f ; ^g ; ^{kwonyj@uci.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AuNC ; gold nanocage ; AuNR ; gold nanorod ; AuNS ; gold nanoshell ; Bcl-2 ; B-cell lymphoma ; BRAFi ; BRAF inhibitor ; BSA ; bovine serum albumin ; CAFs ; cancer associated fibroblasts ; CaP ; calcium phosphate ; CAR ; chimeric antigen receptors ; Chk1i ; checkpoint kinase 1 inhibitor ; CI ; combination index ; CNTs ; carbon nanotubes ; CSCs ; cancer stem cells ; DMA-C60 ; diadduct malonic acid fullerene ; DOX ; Doxorubicin ; DTX ; docetaxel ; ER + ; estrogen receptor positive ; EGCG ; Epigallocatechin gallate ; FA ; folic ac

刊名：Advanced Drug Delivery Reviews

出版年：2016

9.PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells

关键词：API5 ; apoptosis inhibitor 5 ; ARF1 ; ADP ribosylation factor 3 ; BCA ; bicinchoninic acid ; BBC3/PUMA ; BCL2 binding component 3 ; BIRC5 ; baculoviral IAP (inhibitor of apoptosis) repeat containing 5 ; CDC25A ; cell division cycle 25A ; CDK4 ; cyclin-dependent kinase 4 ; CDK6 ; cyclin-dependent kinase 6 ; Chk1 ; checkpoint kinase 1 ; FACS ; Fluorescence-activated cell sorting ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; GO ; Gene Ontology ; IGF2 ; insulin-like growth factor 2 ; miRNA ; microRNA ; MRP2 ; ABC transpo

刊名：Toxicology and Applied Pharmacology

出版年：2016

10.Lovastatin protects keratinocytes from DNA damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics

作者：Verena Ziegler¹ ; Anne Albers¹ ; Gerhard Fritz ; ^{fritz@uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author}

关键词：53BP1 ; tumor suppressor p53 binding protein 1 ; ATM ; ataxia telangiectasia mutated ; ATR ; ataxia telangiectasia and Rad3-related ; Chk ; checkpoint kinase ; DSB ; DNA double-strand break ; DDR ; DNA damage response ; DNA-PKcs ; DNA-dependent protein kinase ; catalytic subunit ; Doxo ; doxorubicin ; 5-FU ; 5-fluorouracil ; γH2AX ; Ser139 phosphorylated histone H2AX ; HU ; hydroxyurea ; IR ; ionizing radiation ; JNK ; c-Jun N-terminal kinase ; Kap1 ; KRAB-associated protein 1 ; Lova ; HMG-CoA-reductase inhibitor lovastatin

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

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