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在“Elsevier电子期刊”中，命中：339条，耗时：小于0.01 秒

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1.MiRNA-30e mediated cardioprotection of ACE2 in rats with Doxorubicin-induced heart failure through inhibiting cardiomyocytes autophagy

作者：Lei Lai ; Junzhu Chen ; ^{c_junzhu@163.com} ; Ningfu Wang ; Gangjie Zhu ; Xu Duan ; Feng Ling

关键词：rhACE2 ; Autophagy ; Beclin-1 ; LC3-II/I ; Caspase-3

刊名：Life Sciences

出版年：2017

2.Comprehensive in vitro cardiac safety assessment using human stem cell technology: Overview of CSAHi HEART initiative

作者：Kiyoshi Takasuna^a ; ^b ; ^c ; ^{takasuna.kiyoshi.a3@daiichisankyo.co.jp} ; Keiichi Asakura^b ; ^c ; ^d ; Seiichi Araki^b ; ^c ; ^e ; Hiroyuki Ando^b ; ^c ; ^f ; Katsuyuki Kazusa^b ; ^c ; ^g ; Takashi Kitaguchi^b ; ^c ; ^h ; Takeshi Kunimatsu^b ; ^c ; ⁱ ; Shinobu Suzuki^b ; ^c ; ^j ; Norimasa Miyamoto^b ; ^c ; ^k

关键词：CSAHi ; Consortium for Safety Assessment using Human iPS Cells ; FPDc10 ; concentration inducing FPDc prolongation by 10% ; CMIS ; cell motion imaging system ; hiPS-CMs ; human induced pluripotent stem cell-derived cardiomyocytes ; CRD ; contraction-relaxation duration ; IBD10 ; impedance-based duration from 10% rising to 10% falling amplitude ; PWD90 ; peak width duration at 90% amplitude ; MEA ; multi-electrode array ; CPMP ; committee for proprietary medicinal products ; APD ; action potential duration ; TdP ; To

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2017

3.Sirtuin 1 protects the aging heart from contractile dysfunction mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific Sirtuin 1 knockout mouse model

作者：Yu-Juei Hsu^a ; ^b ; Shih-Che Hsu^b ; Chiao-Po Hsu^c ; Yen-Hui Chen^d ; Yung-Lung Chang^b ; Junichi Sadoshima^e ; Shih-Ming Huang^b ; Chien-Sung Tsai^f ; ^g ; Chih-Yuan Lin^g ; ^{linrock@ms26.hinet.net}

关键词：Sirtuin 1 ; Contractile dysfunction ; Endoplasmic reticulum stress ; Apoptosis ; Aging

刊名：International Journal of Cardiology

出版年：2017

4.I-Wire Heart-on-a-Chip I: Three-dimensional cardiac tissue constructs for physiology and pharmacology

作者：Veniamin Y. Sidorov^a ; ^b ; Philip C. Samson^a ; ^c ; Tatiana N. Sidorova^d ; Jeffrey M. Davidson^e ; ^f ; Chee C. Lim^d ; John P. Wikswo^a ; ^b ; ^c ; ^g ; ^{john.wikswo@vanderbilt.edu}

关键词：Cardiac tissue engineering ; Frank-Starling relationship ; Force-frequency relationship ; Cardiac tissue elasticity ; Auxotonic contraction

刊名：Acta Biomaterialia

出版年：2017

5.Optical Stimulation of iPS Cardiomyocytes allows Brand New Insights into Contractility and Electropyhsiology Conjunctions

刊名：Biophysical Journal

出版年：2017

6.Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment

作者：Xiaoyu Zhang^a ; Liang Guo^b ; Haoyu Zeng^c ; Stephen L. White^d ; Michael Furniss^b ; Bharathi Balasubramanian^c ; Edward Lis^c ; Armando Lagrutta^c ; Frederick Sannajust^c ; Li Leyna Zhao^a ; Biao Xi^a ; Xiaobo Wang^a ; Myrtle Davis^e ; Yama A. Abassi^a ; ^{yabassi@aceabio.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Cardiomyocytes ; CardioECR ; Contractility ; Arrhythmia ; iPSC

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

7.Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform

作者：Chris Denning^a ; ^{chris.denning@nottingham.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Viola Borgdorff^a ; James Crutchley^a ; Karl S.A. Firth^a ; Vinoj George^a ; Spandan Kalra^a ; Alexander Kondrashov^a ; Minh Duc Hoang^a ; Diogo Mosqueira^a ; Asha Patel^a ; Ljupcho Prodanov^a ; Divya Rajamohan^a ; William C. Skarnes^b ; James G.W. Smith^a ; Lorraine E. Young^a

关键词：Human embryonic stem cells ; Human induced pluripotent stem cells ; Cas9/CRISPR genome editing ; Cardiomyocytes ; Drug screening ; Disease modelling ; Maturation factors ; Muscular thin films ; Engineered heart tissue ; Automated scalability ; High content platforms ; Calcium imaging ; Electrophysiology ; Mitochondria ; Contractility

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

8.Micropost arrays for measuring stem cell-derived cardiomyocyte contractility

作者：Kevin M. Beussman^a ; Marita L. Rodriguez^a ; Andrea Leonard^a ; Nikita Taparia^a ; Curtis R. Thompson^a ; Nathan J. Sniadecki^a ; ^b ; ^{nsniadec@uw.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Microposts ; Induced pluripotent stem cells ; Cardiomyocytes ; Soft lithography ; Cell mechanics

刊名：Methods

出版年：2016

9.Assessment of drug-induced arrhythmic risk using limit cycle and autocorrelation analysis of human iPSC-cardiomyocyte contractility

作者：R. Jason Kirby^a ; ¹ ; Feng Qi^b ; ¹ ; Sharangdhar Phatak^a ; ¹ ; Layton H. Smith^a ; Siobhan Malany^a ; ^{smalany@sbpdiscovery.org" class="auth_mail" title="E-mail the corresponding author}

关键词：Human induced pluripotent stem cell cardiomyocytes (hiPSC-CMs) ; Arrhythmia ; Label-free impedance ; Autocorrelation ; Limit cycle ; Python v2.7 software

刊名：Toxicology and Applied Pharmacology

出版年：2016

10.Block of Na⁺/Ca²⁺ exchanger by SEA0400 in human right atrial preparations from patients in sinus rhythm and in atrial fibrillation

关键词：Sodium-calcium exchanger ; NCX current ; SEA0400 ; Human right atrial cardiomyocytes ; Atrial fibrillation

刊名：European Journal of Pharmacology

出版年：2016

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