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在“Elsevier电子期刊”中，命中：15,760条，耗时：0.1959379 秒

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1.TGF-β1 stimulates movement of renal proximal tubular epithelial cells in a three-dimensional cell culture via an autocrine TGF-β2 production

作者：Deyi Luo^a ; ^b ; ^c ; ^{luodeyi1985@163.com} ; Qiunong Guan^b ; ^c ; ^{Qiunong@hotmail.com} ; Kunjie Wang^a ; ^{wangkj@scu.edu.cn} ; Christopher Y.C. Nguan^b ; ^{Chris.nguan@ubcurology.com} ; Caigan Du^b ; ^c ; ^{caigan@mail.ubc.ca}

关键词：Kidney ; Tubular epithelial cells ; Cell migration ; 3D culture ; TGF-β ; Signaling transduction

刊名：Experimental Cell Research

出版年：2017

2.Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors

作者：Mattia Volta ; ^{mattia.volta@eurac.edu} ; Alexandros A. Lavdas ; Julia Obergasteiger ; Christa Ü ; berbacher ; Anne Picard ; Peter P. Pramstaller ; Andrew A. Hicks ; Corrado Corti ; ^{corrado.corti@eurac.edu}

关键词：aSyn ; Alpha-synuclein ; PD ; Parkinson's disease ; PLCβ1 ; phospholipase Cβ1 ; PI(4 ; 5)P2 ; phosphoinositide-4 ; 5-bisphosphate ; Gq-PCRs ; Gq protein-coupled receptors ; IP3 ; inositol-14 ; 5-trisphosphate ; DAG ; diacylglycerol ; PKC ; protein kinase C ; MAPKs ; mitogen-activated protein kinase ; WT ; wild-type ; ERK1/2 ; extracellular-signal regulated kinase 1/2 ; 5-HT ; serotonin ; (CHO) ; Chinese hamster ovary cells ; FBS ; fetal bovine serum ; AP-1 ; activator protein-1 ; RT ; room temperature ; 5-HT ; serotonin ; SERCA ; sarc

刊名：Cellular Signalling

出版年：2017

3.Re-expression of cell cycle markers in aged neurons and muscles: Whether cells should divide or die?

作者：Renu Sharma ; Dhiraj Kumar ; Niraj Kumar Jha ; Saurabh Kumar Jha ; Rashmi K Ambasta ; Pravir Kumar ; ^{pravirkumar@dce.edu} ; ^{kpravir@gmail.com}

关键词：Post-mitotic cell division ; Signaling cascade ; Neuromuscular degeneration ; Cyclins ; Therapeutics

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

4.PI(3,4,5)P₃ Engagement Restricts Akt Activity to Cellular Membranes

作者：Michael Ebner¹ ; ³ ; Iva Lučić¹ ; ³ ; Thomas A. Leonard¹ ; ² ; ^{thomas.leonard@mfpl.ac.at} ; Ivan Yudushkin¹ ; ² ; ⁴ ; ^{ivan.yudushkin@mfpl.ac.at}

关键词：protein kinase B/Akt ; AGC kinases ; allostery ; cellular signaling ; signal transduction ; fluorescence correlation spectroscopy ; fluorescence cross-correlation spectroscopy ; cellular membranes ; phosphatidylinositol-34 ; 5-trisphosphate ; protein phosphatases

刊名：Molecular Cell

出版年：2017

5.Rapamycin inhibits the proliferation of endothelial cells in hemangioma by blocking the mTOR-FABP4 pathway

作者：Ying Wang¹ ; ^a ; Jiarui Chen¹ ; ^a ; Weiqing Tang^b ; Yanping Zhang^a ; Xiaoyan Li^a ; ^{chhshent@126.com}

关键词：HemECs ; hemangioma derived endothelial cells ; HDVECs ; human dermal microvascular endothelial cells ; ECs ; endothelial cells ; VEGFA ; vascular endothelial growth factor A ; mTOR ; mammalian target of rapamycin ; HIF ; hypoxia inducible factor ; FABP4 ; fatty acid-binding protein4

刊名：Biomedicine & Pharmacotherapy

出版年：2017

6.Signal transduction analysis of the NLRP3-inflammasome pathway after cellular damage and its paracrine regulation

作者：Denise Veltman^a ; Thessa Laeremans^a ; Egle Passante^b ; Heinrich J. Huber^a ; ^c ; ¹ ; ^{heinrich.huber@ovgu.de}

关键词：Signal transduction modelling ; NLRP3-Inflammasome ; Interferons ; Inflammatory diseases ; Ordinary Differential Equations

刊名：Journal of Theoretical Biology

出版年：2017

7.A novel peptide, 9R-P201, strongly inhibits the viability, proliferation and migration of liver cancer HepG2 cells and induces apoptosis by down-regulation of FoxM1 expression

作者：Zhenfei Bi ; Wenrong Liu ; Ruofang Ding ; Yiran Wu ; Rongkun Dou ; Wenwen Zhang ; Xue Yuan ; Xinrong Liu ; Lili Xiong ; Zhiyun Guo ; ^{zhiyunguo@gmail.com} ; Canquan Mao ; ^{maocq@home.swjtu.edu.cn}

关键词：FoxM1-DBD ; 9R-P201 ; HepG2 cells ; Viability ; Apoptosis

刊名：European Journal of Pharmacology

出版年：2017

8.Modulation of VEGF receptor 2 signaling by protein phosphatases

作者：Federico Corti ; ^{federico.corti@yale.edu} ; Michael Simons ; ^{michael.simons@yale.edu}

关键词：AMD ; age-related macular degeneration ; BrdU ; bromodeoxyuridine ; Cys ; cysteine ; DR ; diabetic retinopathy ; DUSP ; dual specificity phosphatase ; E ; embryonic day ; EC ; endothelial cells ; ECM ; extracellular matrix ; ER ; endoplasmic reticulum ; HUVEC ; human umbilical vein endothelial cells ; p-Ser/p-Thr ; phospho-serine/phospho-threonine ; p-Tyr ; phospho-tyrosine ; PTP ; protein tyrosine phosphatase ; R&D ; research and development ; ROP ; retinopathy of prematurity ; ROS ; reactive oxygen species ; RTK ; receptor ty

刊名：Pharmacological Research

出版年：2017

9.The Evolution of Oncology Companion Diagnostics from Signal Transduction to Immuno-Oncology

作者：Nicholas C. Dracopoli¹ ; ^{ndracopo@its.jnj.com} ; Mark S. Boguski² ; ^{mark.boguski@precisionready.com}

关键词：immunotherapy ; precision medicine ; predictive biomarkers ; signal transduction inhibitors

刊名：Trends in Pharmacological Sciences

出版年：2017

10.Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages

作者：Antonio J. Ruiz-Alcaraz^a ; ^ajruiz@um.es ; Marí ; a Tristá ; n-Manzano^a ; Antonio Guirado^b ; Jesú ; s Gá ; lvez^c ; Marí ; a Martí ; nez-Esparza^a ; Pilar Garcí ; a-Peñ ; arrubia^a ; ^{pigarcia@um.es}

关键词：ATF ; activating transcription factor ; CCM ; complete culture medium ; ERK ; extracellular signal-regulated kinase ; IKK ; IκB kinase ; IL-6 ; interleukin 6 ; JNK ; c-Jun N-terminal kinase ; LPS ; lipopolysaccharide ; MAPK ; mitogen-activated protein kinase ; NSAIDs ; non-steroidal anti-inflammatory drugs ; NFκB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; PAMP ; pathogen-associated molecular patterns ; PI3K ; phosphatidylinositol 3-kinase ; PKB ; protein kinase B ; PRRs ; PAMP recognition receptors

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

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