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在“Elsevier电子期刊”中，命中：189条，耗时：0.030989 秒

在所有数据库中总计命中：291条

1.Bioevaluation of sixteen ADMDP stereoisomers toward alpha-galactosidase A: Development of a new pharmacological chaperone for the treatment of Fabry disease and potential enhancement of enzyme replacement therapy efficiency

作者：Wei-Chieh Cheng^a ; ^b ; ^{wcheng@gate.sinica.edu.tw" class="auth_mail" title="E-mail the corresponding author} ; Jen-Hon Wang^a ; ^b ; Huang-Yi Li^a ; Sheng-Jhih Lu^a ; Jia-Ming Hu^a ; Wen-Yi Yun^a ; Cheng-Hsin Chiu^a ; Wen-Bin Yang^a ; Yin-Hsiu Chien^c ; Wuh-Liang Hwu^c

关键词：Fabry disease ; Lysosomal α-galactosidase A ; Lysosomal storage diseases ; Enzyme replacement therapy ; Pharmacological chaperone ; Pyrrolidine-based iminosugar

刊名：European Journal of Medicinal Chemistry

出版年：2016

2.Kinetic stability of cystathionine beta-synthase can be modulated by structural analogs of S-adenosylmethionine: Potential approach to pharmacological chaperone therapy for homocystinuria

作者：Tomas Majtan^a ; ¹ ; Angel L. Pey^b ; ¹ ; ^{angelpey@ugr.es" class="auth_mail" title="E-mail the corresponding author} ; Jan P. Kraus^a ; ^{jan.kraus@ucdenver.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Cystathionine beta-synthase ; S-adenosylmethionine ; Kinetic stability ; Calorimetry ; Pharmacological chaperone ; Homocystinuria

刊名：Biochimie

出版年：2016

3.Chemical chaperone treatment for galactosialidosis: Effect of NOEV on β-galactosidase activities in fibroblasts

作者：Mohammad Arif Hossain^a ; ¹ ; Katsumi Higaki^b ; Michiko Shinpo^a ; Eiji Nanba^b ; Yoshiyuki Suzuki^c ; Keiichi Ozono^a ; Norio Sakai^a ; ² ; ^{norio@ped.med.osaka-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：EEG ; electroencephalogram ; NOEV ; N-octyl-4-epi-β-valienamine ; PPCA ; protective protein/cathepsin A ; SEM ; standard error of the mean ; β-gal ; GM1 β-galactosidase

刊名：Brain and Development

出版年：2016

4.From rare to common and back again: 60 years of lysosomal dysfunction

作者：Maria Francisca Coutinho ; ^{francisca_coutinho@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; ^{francisca.coutinho@insa.min-saude.pt" class="auth_mail" title="E-mail the corresponding author} ; Sandra Alves

关键词：SMase ; acid sphingomyelinase ; AD ; Alzheimer disease ; BBB ; blood&ndash ; brain barrier ; CD-MPR ; cation-dependent mannose 6-phosphate receptor ; CI-MPR ; cation-independent mannose 6-phosphate receptor ; CNS ; central nervous system ; CMA ; chaperone-mediated autophagy ; DLB ; dementia with Lewy bodies ; EE ; early endosome ; ER ; endoplasmic reticulum ; ERT ; enzyme replacement therapy ; FTLD ; frontotemporal lobar degeneration ; GD ; Gaucher disease ; GCase ; β-Glucocerebrosidase ; HSC70 ; heat shock cognate 70 ; LE ; la

刊名：Molecular Genetics and Metabolism

出版年：2016

5.ATOX1 gene silencing increases susceptibility to anticancer therapy based on copper ionophores or chelating drugs

作者：Vincenza Barresi^a ; Giorgia Spampinato^a ; Nicolò ; Musso^a ; Angela Trovato Salinaro^a ; Enrico Rizzarelli^b ; Daniele Filippo Condorelli^a ; ^{daniele.condorelli@unict.it" class="auth_mail" title="E-mail the corresponding author}

关键词：Copper ; ATOX1 ; Colon cancer ; Chelating drugs ; Ionophores

刊名：Journal of Inorganic Biochemistry

出版年：2016

6.Chaperone mediated gene therapy for type I sialidosis

作者：Ida Annunziata ; Huimin Hu ; Elida Gomero ; Alessandra d'Azzo

刊名：Molecular Genetics and Metabolism

出版年：2016

7.Antinociceptive effects of a new sigma-1 receptor antagonist (N-(2-morpholin-4-yl-ethyl)-2-(1-naphthyloxy)acetamide) in two types of nociception

关键词：Neuropathic pain ; Arthritic pain ; BD-1063 ; Antagonist sigma-1 receptor ; Morphine ; Antinociceptive

刊名：European Journal of Pharmacology

出版年：2016

8.Targeting transcription factors by small compounds—Current strategies and future implications

作者：Judith Hagenbuchner^b ; Michael J. Ausserlechner^a ; ^{michael.j.ausserlechner@i-med.ac.at" class="auth_mail" title="E-mail the corresponding author}

关键词：bHLH ; basic helix-loop-helix ; BET ; bromodomain and extraterminal ; DBD ; DNA-binding domain ; DNMT ; DNA-methyltransferases ; HSP ; heat shock proteins ; HAT ; histone acetyltransferase ; HIF1 ; hypoxia-inducible factor-1 ; HDAC ; histone-deacetylase ; KLF10 ; Kruppel-like factor 10 ; Mycro ; Myc activity-reducing organic ; PAS ; Per-ARNT-Sim domain ; PK083 ; PhiKan083 ; P-TEFb ; positive transcription elongation factor b ; RORγt ; retinoic acid receptor-related orphan receptor gamma t ; Pol II ; RNA polymerase II ; STAT3

刊名：Biochemical Pharmacology

出版年：2016

9.Heat shock proteins in the retina: Focus on HSP70 and alpha crystallins in ganglion cell survival

作者：Natik Piri^a ; ^b ; ^{piri@jsei.ucla.edu" class="auth_mail" title="E-mail the corresponding author} ; Jacky M.K. Kwong^a ; Lei Gu^a ; Joseph Caprioli^a ; ^b

关键词：Heat shock protein ; Retina ; Ganglion cells ; Optic nerve ; Glaucoma ; Neuroprotection

刊名：Progress in Retinal and Eye Research

出版年：2016

10.Ste20-like kinase, SLK, activates the heat shock factor 1 - Hsp70 pathway

作者：Andrey V. Cybulsky ; ^{andrey.cybulsky@mcgill.ca" class="auth_mail" title="E-mail the corresponding author} ; Julie Guillemette ; Joan Papillon

关键词：GEC ; glomerular epithelial cell ; GFP ; green fluorescent protein ; HA ; hemaglutinin antigen epitope tag ; HSF1 ; heat shock factor 1 ; ΔHSF1 ; constitutively active HSF1 ; Hsp ; heat shock protein ; JNK ; c-Jun N-terminal kinase ; PLK ; polo-like kinase

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

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