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在“Elsevier电子期刊”中，命中：815条，耗时：0.0279912 秒

在所有数据库中总计命中：1,204条

1.Phase 2 Study of Erlotinib in Combination With Linsitinib (OSI-906) or Placebo in Chemotherapy-Naive Patients With Non-Small-Cell Lung Cancer and Activating Epidermal Growth Factor Receptor Mutations

作者：Natasha B. Leighl¹ ; Naiyer A. Rizvi² ; Lopes Gilberto de Lima Jr.³ ; ⁴ ; Wichit Arpornwirat⁵ ; Charles M. Rudin⁶ ; Alberto A. Chiappori⁷ ; Myung-Ju Ahn⁸ ; Laura Q.M. Chow⁹ ; Lyudmila Bazhenova¹⁰ ; Arunee Dechaphunkul¹¹ ; Patrapim Sunpaweravong¹² ; Keith Eaton¹³ ; ¹⁴ ; Jihong Chen¹⁵ ; Sonja Medley¹⁵ ; Srinivasu Poondru¹⁵ ; Margaret Singh¹⁵ ; Joyce Steinberg¹⁵ ; Rosalyn A. Juergens¹⁶ ; ^{juergensr@hhsc.ca} ; Shirish M. Gadgeel¹⁷ ; ¹⁸

关键词：Combination ; Epidermal growth factor receptor inhibitor ; First-line therapy ; Insulin-like growth factor-1 inhibitor ; Tyrosine kinase inhibitor

刊名：Clinical Lung Cancer

出版年：2017

2.Cellular and molecular mechanisms underlying alcohol-induced aggressiveness of breast cancer

作者：Yongchao Wang^a ; Mei Xu^a ; Zun-ji Ke^b ; Jia Luo^a ; ^b ; ^{jialuo888@uky.edu}

关键词：ADH ; alcohol dehydrogenase ; ALDH2 ; aldehyde dehydrogenase ; C3G ; cyanidin-3-glucoside ; CCL2 ; chemokine (CC motif) ligand 2 ; CCR2 ; chemokine (CC motif) receptor 2 ; CSC ; cancer stem cells ; CYP2E1 ; cytochrome P450 2E1 ; ECM ; extracellular matrix ; EGFR ; epidermal growth factor receptor ; EMT ; epithelial-mesenchymal transition ; MCP-1 ; monocyte chemoattractant protein 1 ; MMPs ; matrix metalloproteinases ; NOX ; NADPH oxidase ; ROS ; reactive oxygen species ; VEGF ; vascular endothelial growth factor

刊名：Pharmacological Research

出版年：2017

3.Adenosine A_2A and A_2B Receptors Differentially Modulate Keratinocyte Proliferation: Possible Deregulation in Psoriatic Epidermis

作者：Rosa M. André ; s¹ ; ² ; Marí ; a Carmen Terencio¹ ; ² ; Jorge Arasa¹ ; ² ; Miguel Payá ; ¹ ; ² ; Francisca Valcuende-Cavero³ ; ⁴ ; Pedro Navaló ; n⁵ ; Marí ; a Carmen Montesinos¹ ; ² ; ^{m.carmen.montesinos@uv.es}

关键词：AR ; adenosine receptors ; BAY ; BAY60&ndash ; 6583 ; CGS ; CGS-21680 ; iCa2+ ; intracellular calcium ; MRS ; MRS-1706 ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; NECA ; 5'-N-ethylcarboxamidoadenosine ; NHEK ; normal human epidermal keratinocyte ; SCH ; SCH-442416 ; TNF ; tumor necrosis factor ; TPA ; 12-O-tetradecanoylphorbol-13-acetate

刊名：Journal of Investigative Dermatology

出版年：2017

4.Staphylococcus aureus Induces Increased Serine Protease Activity in Keratinocytes

作者：Michael R. Williams¹ ; Teruaki Nakatsuji¹ ; James A. Sanford¹ ; Alison F. Vrbanac¹ ; Richard L. Gallo¹ ; ^{rgallo@ucsd.edu}

关键词：AD ; atopic dermatitis ; DSG-1 ; desmoglein-1 ; FLG ; filaggrin ; KLK ; kallikrein ; MMP ; matrix metalloproteinase ; NHEK ; normal human epidermal keratinocyte ; Pro-FLG ; profilaggrin ; RT ; room temperature ; siRNA ; small interfering RNA ; TSB ; tryptic soy broth

刊名：Journal of Investigative Dermatology

出版年：2017

5.Ganglioside GM3 Mediates Glucose-Induced Suppression of IGF-1 Receptor-Rac1 Activation to Inhibit Keratinocyte Motility

作者：Duncan Hieu M. Dam¹ ; ² ; Xiao-Qi Wang¹ ; ² ; Sarah Sheu¹ ; Mahima Vijay¹ ; Desmond Shipp¹ ; Luke Miller¹ ; Amy S. Paller¹ ; ^{apaller@northwestern.edu}

关键词：AS ; antisense oligonucleotide ; GCS ; glucosylceramide synthase ; GCSI ; glucosylceramide synthase inhibitor ; GM3S ; ganglioside GM3 synthase ; IGF-1 ; insulin-like growth factor-1 ; IGF1R ; insulin-like growth factor-1 receptor ; IR ; insulin receptor ; M2D3 ; GM2/GD2 and GD3 synthases ; NHEK ; normal human epidermal keratinocyte ; shRNA ; short hairpin RNA ; siRNA ; small interfering RNA ; SNA ; spherical nucleic acid

刊名：Journal of Investigative Dermatology

出版年：2017

6.New therapeutic strategies for malignant pleural mesothelioma

作者：Mara A. Bonelli ^{mara.bonelli@unipr.it} ; Claudia Fumarola ^{claudia.fumarola@unipr.it} ; Silvia La Monica ^{silvia.lamonica@unipr.it} ; Roberta Alfieri ; ^{roberta.alfieri@unipr.it}

关键词：AE ; adverse event ; CTLA-4 ; cytotoxic T-lymphocyte-associated antigen 4 ; EGFR ; epidermal growth factor receptor ; FAK ; focal adhesion kinase ; IGFR ; insulin growth factor receptor ; MPM ; malignant pleural mesothelioma ; MTD ; maximum tolerated dose ; mTOR ; mammalian target of rapamycin ; NSCLC ; non-small cell lung cancer ; OS ; overall survival ; PD ; progressive disease ; PFS ; progression free survival ; PD-1 ; programmed death 1 ; PDL-1 ; programmed death ligand 1 ; PI3K ; phosphatidylinositol 3-kinase ; PR ; part

刊名：Biochemical Pharmacology

出版年：2017

7.Lupus Skin Is Primed for IL-6 Inflammatory Responses through a Keratinocyte-Mediated Autocrine Type I Interferon Loop

作者：Jasmine N. Stannard¹ ; ² ; Tamra J. Reed¹ ; Emily Myers³ ; Lori Lowe⁴ ; ⁵ ; Mrinal K. Sarkar⁴ ; Xianying Xing⁴ ; Johann E. Gudjonsson⁴ ; J. Michelle Kahlenberg¹ ; ^{mkahlenb@med.umich.edu}

关键词：CLE ; cutaneous lupus erythematosus ; DLE ; discoid lupus erythematosus ; SCLE ; subacute cutaneous lupus erythematosus ; SLE ; systemic lupus erythematosus ; TLR ; toll-like receptor

刊名：Journal of Investigative Dermatology

出版年：2017

8.In Vitro Evaluation of Novel Phenytoin-Loaded Alkyd Nanoemulsions Designed for Application in Topical Wound Healing

作者：Siew Yong Teo¹ ; Mei Yeng Yew² ; Siang Yin Lee³ ; ⁴ ; ^{leesiangyin@lgm.gov.my} ; Michael J. Rathbone¹ ; ⁵ ; Seng Neon Gan⁶ ; Allan G.A. Coombes³

关键词：alkyd nanoemulsion ; phenytoin ; topical ; wound healing

刊名：Journal of Pharmaceutical Sciences

出版年：2017

9.From pure compounds to complex exposure: Effects of dietary cadmium and lignans on estrogen, epidermal growth factor receptor, and mitogen activated protein kinase signaling in vivo

作者：Imran Ali^a ; ² ; ^{imran.ali@ki.se" class="auth_mail" title="E-mail the corresponding author} ; Teija Hurmerinta^b ; ² ; Tarja Nurmi^c ; Marika Berglund^a ; Joelle Rü ; egg^d ; ^e ; Matti Poutanen^f ; ^g ; Krister Halldin^a ; Sari Mä ; kelä ; ^b ; ^g ; Pauliina Damdimopoulou^b ; ¹

关键词：ADME ; absorption ; distribution ; metabolism and excretion ; bw ; body weight ; E2 ; 17β-estradiol ; EDC ; endocrine disruptive chemical ; EGFR ; epidermal growth factor receptor ; ERE ; estrogen response element ; ERE-luc ; ERE-luciferase ; GNX ; gonadiectomized ; LUMA ; luminometric methylation assay ; MAPK ; mitogen activated protein kinase ; NOEL ; no observed effect level ; OVX ; ovariectomized ; RLU ; relative light units

刊名：Toxicology Letters

出版年：2016

10.Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: An Analysis of Triggers and Implications for Improving Prevention

作者：Monica A. Miliszewski ; MD^a ; ¹ ; Mark G. Kirchhof ; MD ; PhD^a ; ^b ; ¹ ; Sheena Sikora ; MD^c ; Anthony Papp ; MD^c ; Jan P. Dutz ; MD^a ; ^d ; ^{dutz@interchange.ubc.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：Allopurinol ; Drug reactions ; HLA testing ; Phenytoin ; Stevens-Johnson syndrome ; Sulfamethoxazole-trimethoprim ; Toxic epidermal necrolysis

刊名：The American Journal of Medicine

出版年：2016

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