搜索页_+G-protein+coupled+receptor+agonist

常用资源

电子图书

期刊论文

学位会议

外文资源

特色专题

内部出版物

Wiley电子期刊(25)	SpringerLink电子期刊(566)	Elsevier电子期刊(2458)
Springer电子图书(1)	NATURE电子期刊(56)	ACS电子期刊(278)

在“Elsevier电子期刊”中，命中：2,458条，耗时：0.1389358 秒

在所有数据库中总计命中：3,384条

1.Estrogen stabilizes hypoxia-inducible factor 1α through G protein-coupled estrogen receptor 1 in eutopic endometrium of endometriosis

作者：Ling Zhang ; M.D.^a ; Wenqian Xiong ; M.D.^a ; Na Li ; M.D.^a ; Hengwei Liu ; M.D.^a ; Haitang He ; M.D.^a ; Yu Du ; M.D.^a ; Zhibing Zhang ; Ph.D.^b ; Yi Liu ; Ph.D.^a ; ^{Liqun94@163.com}

关键词：Endometriosis ; Estrogen ; G protein-coupled estrogen receptor (GPER) ; hypoxia-inducible factor 1α (HIF-1α)

刊名：Fertility and Sterility

出版年：2017

2.Estimation of the receptor-state affinity constants of ligands in functional studies using wild type and constitutively active mutant receptors: Implications for estimation of agonist bias

作者：Frederick J. Ehlert^a ; ^b ; ^{fjehlert@uci.edu} ; Richard S.L. Stein^b

关键词：Receptor state affinity constants ; Constitutive activity ; Agonist bias ; System bias ; Monod-Wyman-Changeux model ; Observed affinity ; Efficacy ; Receptor activation ; Active state ; Inactive state

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2017

3.Metabotropic glutamate receptors and neurodegenerative diseases

作者：Fabiola M. Ribeiro^a ; Luciene B. Vieira^b ; Rita G.W. Pires^c ; Roenick P. Olmo^a ; Stephen S.G. Ferguson^d ; ^{sferguso@uottawa.ca}

关键词：AMPA ; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid ; Aβ ; amyloid β peptide ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; BDNF ; brain derived neurotrophic factor ; BF ; basal forebrain ; CGA ; chromogranin A ; CNS ; central nervous system ; DAG ; diacylghycerol ; ERK ; extracellular signal-regulated kinase ; GABA ; gamma-aminobutyric acid ; GDNF ; glial cell line-derived neurotrophic factor ; GIRK ; inward rectifying K+ channels ; GP ; globus pallidum ; GPe ; globus pallidum externa ; GPCR ; G

刊名：Pharmacological Research

出版年：2017

4.High affinity binding of the peptide agonist TIP-39 to the parathyroid hormone 2 (PTH₂) receptor requires the hydroxyl group of Tyr-318 on transmembrane helix 5

作者：Richard E. Weaver^a ; Juan C. Mobarec^c ; Mark J. Wigglesworth^b ; ¹ ; Christopher A. Reynolds^c ; Dan Donnelly^a ; ^{d.donnelly@leeds.ac.uk}

关键词：Parathyroid hormone ; PTH ; GPCR ; Agonist ; Receptor ; TIP39

刊名：Biochemical Pharmacology

出版年：2017

5.Novel indole-based compounds that differentiate alkylindole-sensitive receptors from cannabinoid receptors and microtubules: Characterization of their activity on glioma cell migration

作者：Susan Fung^a ; ^b ; Cong Xu^a ; Ernest Hamel^c ; James B. Wager-Miller^d ; Grace Woodruff^a ; Aaron Miller^a ; Christina Sanford^a ; Ken Mackie^d ; Nephi Stella^a ; ^e ; ^{nstella@uw.edu}

关键词：2-AG ; arachidonoylglycerol ; AI ; alkylindole ; CB ; cannabinoid ; CB1 ; cannabinoid receptor 1 ; CB2 ; cannabinoid receptor 2 ; CSA4 ; combretastatin A4 ; DBT ; delayed Brain Tumor ; HA ; hemagglutinin ; LPA ; lysophosphatidic acid ; GBM ; glioblastoma multiforme ; SAR ; structure activity relationship ; THC ; tetrahydrocannabinol ; WIN-2 ; WIN55212-2

刊名：Pharmacological Research

出版年：2017

6.Impaired thromboxane receptor dimerization reduces signaling efficiency: A potential mechanism for reduced platelet function in vivo

作者：Valé ; rie Capra^a ; ^b ; ¹ ; ^{Valerie.Capra@unimi.it} ; Mario Mauri^c ; ¹ ; ^{mario.mauri@unimib.it} ; Francesca Guzzi^c ; ^{francesca.guzzi@unimib.it} ; Marta Busnelli^d ; ^e ; ^{m.busnelli@in.cnr.com} ; Maria Rosa Accomazzo^a ; ^{Maria.Accomazzo@unimi.it} ; Pascale Gaussem^f ; ^{pascale.gaussem@univ-paris5.fr} ; Shaista P. Nisar^g ; ^{shaista.nisar@bristol.ac.uk} ; Stuart J. Mundell^g ; ^{s.j.mundell@bristol.ac.uk} ; Marco Parenti^c ; ^{marco.parenti@unimib.it} ; G. Enrico Rovati^a ; ^{Genrico.Rovati@unimi.it}

关键词：U46619 (PubChem CID ; 5311493) ; (Z)-7-[(1S ; 2S ; 3R ; 4R)-3-[(E ; 3S)-3-hydroxyoct-1-enyl]-5-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid ; I-BOP (PubChem CID ; 51015454) ; (Z)-7-[(1S ; 2S ; 3S ; 4R)-3-[(E ; 3R)-3-hydroxy-4-(4-iodophenoxy)but-1-enyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid ; Pinane Thromboxane A2 (PTA2) (PubChem CID ; 25834471) ; (Z)-7-[(1S ; 3R ; 4R ; 5S)-3-[(E ; 3R)-3-hydroxyoct-1-enyl]-6 ; 6-dimethyl-4-bicyclo[3.1.1]heptanyl]hept-5-enoic acid ; SQ29 ; 548 (PubChem CID ; 6437074) ; (Z)-7-[(1R ; 2R ; 3R ; 4S)

刊名：Biochemical Pharmacology

出版年：2017

7.Stabilizing effects of G protein on the active conformation of adenosine A₁ receptor differ depending on G protein type

作者：Michihiro Tateyama^a ; ^b ; ^{tateyama@nips.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Yoshihiro Kubo^a ; ^b ; ^{ykubo@nips.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：G protein coupled receptor ; Adenosine A1 receptor ; Fö ; rster resonance energy transfer (FRET) ; Conformational change ; G protein coupling

刊名：European Journal of Pharmacology

出版年：2016

8.Lactate produced during labor modulates uterine inflammation via GPR81 (HCA₁)

作者：Ankush Madaan ; BPharm ; MSc^a ; ^c ; ^e ; ¹ ; Mathieu Nadeau-Vallée ; BSc^a ; ^c ; ^d ; ¹ ; Jose Carlos Rivera ; PhD^f ; Dima Obari ; MSc^d ; Xin Hou ; MD ; PhD^a ; ^c ; Estefania Marin Sierra ; BSc^a ; ^c ; ^e ; Sylvie Girard ; PhD^b ; David M. Olson ; PhD^g ; Sylvain Chemtob ; MD ; PhD^a ; ^c ; ^d ; ^e ; ^f ; ^{sylvain.chemtob@umontreal.ca}

关键词：CCL2 ; chemokine ; chorioamnionitis ; cytokine ; endotoxin ; GPR81 ; inflammation ; interleukin ; interleukin-1 ; interleukin-6 ; labor ; lactate ; lactic acid ; lipopolysaccharide ; PGHS2 ; mouse ; myometrium ; parturition ; preterm labor ; pyruvate ; spontaneous labor

刊名：American Journal of Obstetrics and Gynecology

出版年：2017

9.Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data

作者：Lisa A. Stott^a ; David A. Hall^b ; Nicholas D. Holliday^a ; ^{nicholas.holliday@nottingham.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：CRC ; concentration response curve ; EC50 ; effective agonist concentration for 50% maximum response ; Emax ; maximum system response ; GPCR ; G protein coupled receptor ; D2R ; dopamine D2 receptor ; GTPγS ; guanosine 5&prime ; -O-[γ-thio]triphosphate ; KA ; agonist equilibrium dissociation constant ; KE ; concentration of agonist&ndash ; receptor complex which produces a half maximal effect ; MAPK ; mitogen activated protein kinase ; RAi ; relative intrinsic activity ratio ; Rmax ; maximum agonist response ; RT ; total

刊名：Biochemical Pharmacology

出版年：2016

10.Activation of GPER ameliorates experimental pulmonary hypertension in male rats

作者：Allan K. Alencar^a ; ¹ ; Guilherme C. Montes^a ; ¹ ; Tadeu Montagnoli^a ; Ananssa M. Silva^a ; Sabrina T. Martinez^b ; Aline G. Fraga^a ; Hao Wang^c ; Leanne Groban^c ; Roberto T. Sudo^a ; Gisele Zapata-Sudo^a ; ^{gsudo@icb.ufrj.br}

关键词：GPER ; Monocrotaline ; Vascular remodeling ; Right ventricular dysfunction

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

按检索点细分(2458)

题名(71)

关键词(104)

文摘(1945)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700