搜索页_ G2/M cell cycle arrest

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在“Elsevier电子期刊”中，命中：1,079条，耗时：0.1369343 秒

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1.G₂/M cell cycle arrest on HT-29 cancer cells and toxicity assessment of triphenylphosphanegold(I) carbonimidothioates, Ph₃PAu[SC(OR) = NPh], R = Me, Et, and iPr, during zebrafish development

作者：Kah Kooi Ooi^a ; ^b ; Chien Ing Yeo^b ; Theventhiran Mahandaran^c ; Kok Pian Ang^a ; Abdah Md Akim^a ; Yoke-Kqueen Cheah^a ; Hoi-Ling Seng^d ; ^{hoilings@sunway.edu.my} ; Edward R.T. Tiekink^b ; ^{edwardt@sunway.edu.my}

关键词：Annexin V-FITC ; Recombinant annexin V conjugated to fluorescein isothiocyanate ; APAF-1 ; Apoptotic protease activating factor 1 ; ATR ; Ataxia telangiectasia and Rad3-related ; Bax ; Apoptosis regulator ; Bcl-2 ; B-cell lymphoma 2 ; BIRC-5 ; Baculoviral inhibitor of apoptosis repeat-containing 5/ Survivin ; CCNB1 ; Cyclin B1 ; cdc25C ; Cell division cycle 25C ; CDKN1A ; Cyclin-dependent kinase N1A ; CDK2 ; Cyclin-dependent kinase 2 ; CDK4 ; Cyclin-dependent kinase 4 ; CHEK1/Chk1 ; Checkpoint kinase 1 ; CHEK2/Chk2 ; Ch

刊名：Journal of Inorganic Biochemistry

出版年：2017

2.MC37, a new mono-carbonyl curcumin analog, induces G2/M cell cycle arrest and mitochondria-mediated apoptosis in human colorectal cancer cells

作者：Baoxia Liang^a ; Ziyi Liu^a ; Yingnan Cao^b ; Cuige Zhu^a ; Yinglin Zuo^a ; Lei Huang^a ; Gesi Wen^a ; Nana Shang^a ; Yu Chen^a ; Xin Yue^a ; Jun Du^a ; Baojian Li^c ; Binhua Zhou^a ; ^{sichuang1984@outlook.com} ; Xianzhang Bu^a ; ^{phsbxzh@mail.sysu.edu.cn}

关键词：NF-κB ; nuclear factor kaapa B ; CDK1 ; cyclin-dependent kinase 1 ; MMP ; mitochondrial membrane potential ; CRC ; colorectal cancer ; DMEM ; Dulbecco's modified Eagle's medium ; PMSF ; phenylmethylsulfonylfluoride ; S.D. ; standard deviation ; PARP ; poly-ADP Ribose polymerase ; SRB ; sulforhodamine B ; TNF-α ; tumor necrosis factor alpha ; DMSO ; dimethyl sulfoxide ; COX-2 ; cyclooxygenase 2 ; FBS ; fetal bovine serum ; VEGF ; vascular endothelial growth factor ; TCA ; trichloroacetic acid ; IL-6 ; interleukin 6 ; SDS-PAGE

刊名：European Journal of Pharmacology

出版年：2017

3.Lx2-32c, a novel semi-synthetic taxane, exerts antitumor activity against prostate cancer cells in vitro and in vivo

作者：Guangyao Lv^a ; ^&dagger ; ; Dengjun Sun^b ; ^&dagger ; ; Jingwen Zhang^a ; Xiaoxia Xie^a ; Xiaoqiong Wu^d ; Weishuo Fang^c ; Jingwei Tian^a ; Chunhong Yan^e ; Hongbo Wang^a ; ^{hongbowangyt@gmail.com} ; Fenghua Fu^a ; ^{fufenghua@sohu.com}

关键词：Lx2-32c ; Cephalomannine ; Prostate cancer ; Microtubule ; Cell cycle arrest ; Apoptosis

刊名：Acta Pharmaceutica Sinica B

出版年：2017

4.A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in multidrug resistance cells

作者：Vanessa Lopes-Rodrigues^a ; ^b ; ^c ; ^h ; Ana Oliveira^d ; ^h ; Marta Correia-da-Silva^d ; ^e ; Madalena Pinto^d ; ^e ; Raquel T. Lima^a ; ^b ; ^f ; Emí ; lia Sousa^d ; ^e ; ^{esousa@ff.up.pt} ; M. Helena Vasconcelos^a ; ^b ; ^g ; ^{hvasconcelos@ipatimup.pt}

关键词：ABC ; ATP-binding cassette ; DMSO ; dimethyl sulfoxide ; EtOAc ; ethyl acetate ; EtOH ; ethanol ; FBS ; fetal bovine serum ; h ; hours ; HPLC ; high-performance liquid chromatography ; HRMS-ESI ; high resolution mass spectrometry-electrospray ionization ; MDR ; multidrug resistance ; MeOH ; methanol ; min ; minutes ; mp ; melting point ; MW ; microwave ; PBS ; phosphate buffered saline ; P-gp ; P-glycoprotein ; r.t. ; room temperature ; SRB ; sulforhodamine B ; THF ; tetrahydrofuran

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

5.Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells

作者：Wei-Jian Sun^a ; ^b ; ¹ ; He Huang^a ; ¹ ; Bin He^b ; ^c ; ¹ ; Dan-Hong Hu^a ; Pi-Hong Li^a ; Yao-Jun Yu^a ; Xiao-Hu Zhou^b ; Zhen Lv^b ; Lei Zhou^a ; Tian-Ye Hu^a ; Zhi-Chao Yao^a ; Ming-Dong Lu^a ; ^{lumingdong126@126.com} ; Xian Shen^a ; ^{13968888872@163.com} ; Zhi-Qiang Zheng^a ; ^{zzq6529921@126.com}

关键词：Romidepsin (PubChem CID ; 5352062) ; 5-Fluorouracil (PubChem CID ; 3385) ; SCH772984 (PubChem CID ; 24866313) ; SB203580 (PubChem CID ; 176155) ; SP600125 (PubChem CID ; 8515) ; Z-VAD-FMK (PubChem CID ; 5497174) ; DMSO (PubChem CID ; 679) ; DAPI (PubChem CID ; 2954) ; Paraformaldehyde (PubChem CID ; 123127) ; Glycine (PubChem CID ; 750) ; Methanol (PubChem CID ; 887) ; Ethanol (PubChem CID ; 702) ; Formaldehyde solution (PubChem CID ; 712) ; Tween 20 (PubChem CID ; 443314)

刊名：Biochemical Pharmacology

出版年：2017

6.Induction of G2/M phase arrest and apoptosis by a new tetrahydroingenol diterpenoid from Euphorbia erythradenia Bioss. in melanoma cancer cells

作者：Faranak Fallahian^a ; ^b ; Mustafa Ghanadian^c ; Mahmoud Aghaei^d ; ^{maghaei@pharm.mui.ac.ir} ; Seyed Mohammad Zarei^e

关键词：Apoptosis ; Melanoma ; Euphorbia erythradenia ; Tetrahydroingenol ; Cancer

刊名：Biomedicine & Pharmacotherapy

出版年：2017

7.MiR-216a decreases MALAT1 expression, induces G2/M arrest and apoptosis in pancreatic cancer cells

作者：Yajing Zhang ; Xiaomei Tang ; Minmin Shi ; Chenlei Wen ; Baiyong Shen ; ^{baiyongshen@outlook.com}

关键词：MiR-216a ; Pancreatic cancer ; Gemcitabine ; MALAT1

刊名：Biochemical and Biophysical Research Communications

出版年：2017

8.Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors

作者：P.V. Sri Ramya^a ; Srinivas Angapelly^a ; Lalita Guntuku^b ; Chander Singh Digwal^a ; Bathini Nagendra Babu^a ; V.G.M. Naidu^b ; ; Ahmed Kamal^a ; ^{ahmedkamal@iict.res.in}

关键词：Curcumin mimics ; Indole ; Cytotoxic ; Apoptosis ; Cell cycle ; Claisen-Schmidt condensation

刊名：European Journal of Medicinal Chemistry

出版年：2017

9.Design and synthesis of novel 2-substituted 11-keto-boswellic acid heterocyclic derivatives as anti-prostate cancer agents with Pin1 inhibition ability

作者：Kun Li^a ; Lei Li^b ; Shuxiang Wang^a ; Xiaojing Li^a ; Tianyi Ma^a ; Dan Liu^a ; ^{sammyld@163.com} ; Yongkui Jing^b ; ^{yongkjing@yahoo.com} ; Linxiang Zhao^a ; ^{linxiang.zhao@vip.sina.com}

关键词：Acetyl-11-keto-β-boswellic acid ; Anti-proliferative activity ; Cyclin D1 ; Cell cycle ; Pin1

刊名：European Journal of Medicinal Chemistry

出版年：2017

10.The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

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