搜索页_ G93A+/+ mice

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在“Elsevier电子期刊”中，命中：332条，耗时：0.0189923 秒

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1.Silencing strategies for therapy of SOD1-mediated ALS

作者：Brigitte van Zundert^a ; ^{bvanzundert@unab.cl} ; Robert H. Brown Jr.^b ; ^{robert.brown@umassmed.edu}

关键词：Therapy ; RNAi ; SOD1 ; ALS

刊名：Neuroscience Letters

出版年：2017

2.Transplantation of bone marrow mononuclear cells prolongs survival, delays disease onset and progression and mitigates neuronal loss in pre-symptomatic, but not symptomatic ALS mice

作者：Gianina Teribele Venturin^a ; ^b ; Samuel Greggio^a ; ^b ; Gabriele Zanirati^b ; Daniel Rodrigo Marinowic^c ; Iuri Marques de Oliveira^d ; Joã ; o Antonio Pê ; gas Henriques^d ; Jaderson Costa DaCosta ; M.D. ; Ph.D^a ; ^b ; ^{jcc@pucrs.br" class="auth_mail" title="E-mail the corresponding author}

关键词：ALS ; amyotrophic lateral sclerosis ; BMMCs ; bone marrow mononuclear cells ; ChAT ; choline acetyltransferase ; EGFP ; enhanced green fluorescent protein ; EGFPBMMC-70 ; SOD1G93A mice transplanted at 70 ; days with BMMCs from C57BL/6-EGFP mice ; EGFPBMMC-110 ; SOD1G93A mice transplanted at 110 ; days with BMMCSs from C57BL/6-EGFP mice ; GLT1 ; glutamate transporter 1 ; MSC ; mesenchymal stem cells ; mSOD1BMMC-70 ; SOD1G93A mice transplanted at 70 ; days with BMMCs from SOD1G93A mice ; mSOD1BMMC-110 ; SOD

刊名：Neuroscience Letters

出版年：2016

3.Caspase 6 has a protective role in SOD1^G93A transgenic mice

作者：Marion C. Hogg ; Mollie R. Mitchem¹ ; Hans-Georg Kö ; nig ; Jochen H.M. Prehn ; ^{prehn@rcsi.ie" class="auth_mail" title="E-mail the corresponding author}

关键词：AD ; Alzheimer's disease ; ALS ; amyotrophic lateral sclerosis ; Casp6/C6 ; caspase 6 ; NGF ; nerve growth factor ; NMJ ; neuromuscular junction ; Ntg ; non-transgenic ; PND ; post-natal day ; SOD1 ; superoxide dismutase 1 ; STS ; staurosporine ; Tg ; transgenic

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2016

4.Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD^G93A mice co-expressing the Copper-Chaperone-for-SOD

作者：Jared R. Williams^a ; Emiliano Trias^b ; ^c ; Pamela R. Beilby^a ; Nathan I. Lopez^a ; Edwin M. Labut^a ; C. Samuel Bradford^a ; Blaine R. Roberts^d ; Erin J. McAllum^d ; ^e ; Peter J. Crouch^d ; ^e ; Timothy W. Rhoads^a ; ¹ ; Cliff Pereira^f ; Marjatta Son^g ; Jeffrey L. Elliott^g ; Maria Clara Franco^h ; Alvaro G. Esté ; vez^h ; Luis Barbeito^c ; Joseph S. Beckman^a ; ^{joe.beckman@oregonstate.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：SOD1 ; Lou Gehrig ; Amyotrophic lateral sclerosis ; Superoxide dismutase ; CCS

刊名：Neurobiology of Disease

出版年：2016

5.Preservation of neuromuscular function in symptomatic SOD1-G93A mice by peripheral infusion of methylene blue

作者：Janet D. Talbot^a ; John N. Barrett^a ; ^b ; Doris Nonner^a ; Zhongsheng Zhang^a ; Kyle Wicomb^a ; Ellen F. Barrett^a ; ^b ; ^{ebarrett2@med.miami.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ALS ; amyotrophic lateral sclerosis ; BgTx ; α-bungarotoxin ; EDL ; extensor digitorum longus muscle ; ETC ; electron transport chain ; fALS ; familial amyotrophic lateral sclerosis ; FF ; fast ; fatiguable muscle ; FUS ; fused in sarcoma/translated in liposarcoma ; MB ; methylene blue ; SOD1 ; superoxide dismutase 1 ; TA ; tibialis anterior muscle ; TDP-43 ; transactive response DNA-binding protein 43 ; YFP ; yellow fluorescent protein

刊名：Experimental Neurology

出版年：2016

6.Moderate modulation of disease in the G93A model of ALS by the compound 2-(2-hydroxyphenyl)-benzoxazole (HBX)

作者：Teresa M. Evans^a ; Arunabh Bhattacharya^b ; Yun Shi^c ; Wenbo Qi^c ; Travis J. Block^d ; Asish Chaudhuri^e ; Alakananda Ray Chaudhuri^f ; Kara Hawker^f ; Holly Van Remmen^g ; ^h ; ^{Holly-VanRemmen@omrf.org" class="auth_mail" title="E-mail the corresponding author}

关键词：Amyotrophic lateral sclerosis ; Mouse model ; Protein aggregation ; Denervation ; Treatment ; Chelation

刊名：Neuroscience Letters

出版年：2016

7.Neuregulin-1 promotes functional improvement by enhancing collateral sprouting in SOD1^G93A ALS mice and after partial muscle denervation

作者：Renzo Mancuso^a ; ^g ; ¹ ; Anna Martí ; nez-Muriana^a ; ¹ ; Tatiana Leiva^a ; David Gregorio^b ; Lorena Ariza^b ; Marta Morell^a ; Jesú ; s Esteban-Pé ; rez^c ; ^d ; Alberto Garcí ; a-Redondo^c ; ^d ; Ana C. Calvo^e ; Gabriela Atencia-Cibreiro^c ; ^d ; Gabriel Corfas^e ; Rosario Osta^f ; Assumpció ; Bosch^b ; Xavier Navarro^a ; ^{xavier.navarro@uab.cat" class="auth_mail" title="E-mail the corresponding author}

关键词：Neuregulin-1 ; Amyotrophic lateral sclerosis ; Neuromuscular junction ; Motoneuron ; Collateral sprouting

刊名：Neurobiology of Disease

出版年：2016

8.Voltage-gated calcium channels are abnormal in cultured spinal motoneurons in the G93A-SOD1 transgenic mouse model of ALS

作者：Qing Chang^a ; ^{qchang1@jhmi.edu" class="auth_mail" title="E-mail the corresponding author} ; Lee J. Martin^a ; ^b

关键词：ALS ; amyotrophic lateral sclerosis ; SOD1 ; superoxide dismutase-1 ; AMPA ; α-amino-3-hydroxy-5-methylisoxazole propionic acid ; VGCC ; voltage-gated Ca2 ; + channel ; PCCa ; persistent Ca2 ; + current ; mSOD1 ; mutant SOD1 ; TEA-Cl ; tetraethylammonium chloride ; 4-AP ; 4-aminopyridine ; TTX ; tetrodotoxin ; AP ; action potential ; PSC ; postsynaptic current ; sEPSC ; spontaneous excitatory postsynaptic current ; sIPSC ; spontaneous inhibitory postsynaptic current ; mEPSC ; miniature excitatory postsynaptic curren

刊名：Neurobiology of Disease

出版年：2016

9.Altered terminal Schwann cell morphology precedes denervation in SOD1 mice

作者：Dario I. Carrasco^a ; Kevin L. Seburn^b ; Martin J. Pinter^a ; ^{mpinter@emory.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Motor neuron disease ; Terminal Schwann cell ; Neurodegeneration ; Motor terminal ; Denervation ; Neuromuscular junction

刊名：Experimental Neurology

出版年：2016

10.Autophagic down-regulation in motor neurons remarkably prolongs the survival of ALS mice

作者：Kuo-Wei Hsueh^a ; ^b ; Tzyy-Wen Chiou^c ; Shu-Fen Chiang^d ; Toru Yamashita^e ; Koji Abe^e ; Cesar V. Borlongan^f ; Paul R. Sanberg^f ; Angela (Yu Hsuan) Huang^g ; Shinn-Zong Lin^b ; ^h ; ¹ ; ^{shinnzong@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author} ; Horng-Jyh Harn^g ; ⁱ ; ¹ ; ^{duke_harn@yahoo.com.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：LC3 ; microtubule-associated protein 1 light chain 3 ; SOD1G93A ; mutant human Cu/Zn superoxide dismutase ; n-BP ; n-butylidenephthalide ; bid ; two times a day ; qd ; one times a day

刊名：Neuropharmacology

出版年：2016

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