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Elsevier电子期刊(232)

在“Elsevier电子期刊”中，命中：232条，耗时：0.0989515 秒

在所有数据库中总计命中：302条

1.Synthesis of novel steroidal agonists, partial agonists, and antagonists for the glucocorticoid receptor

作者：Zhuang Jin^a ; Hua Lin^a ; Sathish Srinivasan^b ; Jerome C. Nwachukwu^b ; Nelson Bruno^b ; Patrick R. Griffin^a ; Kendall W. Nettles^b ; ; Theodore M. Kamenecka^a ; ^{kameneck@scripps.edu}

关键词：AF-1 ; activation function-1 ; AF-2 ; activation function-2 ; AP-1 ; activator protein 1 ; dppp ; 1 ; 3-bis(diphenylphosphino)propane ; DEX ; dexamethasone ; DIEA ; N ; N-diisopropylethylamine ; FKBP5 ; FK506-binding protein 5 ; GR ; glucocorticoid receptor ; GRE ; glucocorticoid-response element ; HATU ; 1-[bis(dimethylamino)methylene]-1H-12 ; 3-triazolo[4 ; 5-b]pyridinium 3-oxid hexafluorophosphate ; IL-6 ; Interleukin-6 ; LBD ; ligand-binding domain ; LPS ; lipopolysaccharide ; MMTV ; mouse mammary tumor virus ; NF-κB ; nuclear

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Lessons from tissue compartment-specific analysis of androgen receptor alterations in prostate cancer

作者：Mark Daniel^a ; ^b ; Scott M. Dehm^b ; ^c ; ^d ; ^dehm@umn.edu

关键词：LHRH ; luteinizing hormone releasing hormone ; ADT ; androgen depletion therapy ; CRPC ; castration-resistant prostate cancer ; CYP17 ; cytochrome P450 c17 ; MR ; mineralocorticoid receptor ; ER ; estrogen receptor ; PR ; progestins receptor ; GR ; glucocorticoid receptor ; NTD ; NH2-terminal domain ; AF-1 ; activation function 1 ; LBD ; ligand bind domain ; ARE ; androgen response element ; RIP ; RNA co-immunoprecipitation ; NCOA ; nuclear receptor coactivator ; NCOR ; nuclear receptor corepressor ; CTC ; circulating tumor c

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

3.Recent progress in the development of protein-protein interaction inhibitors targeting androgen receptor-coactivator binding in prostate cancer

作者：Eric Biron^a ; ^b ; ^{eric.biron@pha.ulaval.ca" class="auth_mail" title="E-mail the corresponding author} ; Franç ; ois Bé ; dard^a ; ^b

关键词：AB ; Sandrogen-binding site ; AF ; activation function ; AR ; androgen receptor ; ARA ; androgen receptor-associated protein ; ARE ; androgen-responsive elements ; BF3 ; binding function 3 ; CBI ; coactivator binding inhibitor ; CBP ; CREB-binding protein ; CPRC ; castration-resistant prostate cancer ; CYP ; cytochrome P450 ; DBD ; DNA-binding domain ; DHT ; 5α-dihydrotestosterone ; ER ; estrogen receptor ; FP ; fluorescence polarization ; GRIP1 ; glutamate receptor interacting protein 1 ; LBD ; ligand-binding domain ; NLS ; n

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2016

4.Structure-based optimization of GRP78-binding peptides that enhances efficacy in cancer imaging and therapy

作者：Sheng-Hung Wang^a ; ¹ ; Andy Chi-Lung Lee^a ; ¹ ; I-Ju Chen^c ; Nai-Chuan Chang^a ; Han-Chung Wu^b ; ^c ; Hui-Ming Yu^c ; Ya-Jen Chang^d ; Te-Wei Lee^d ; Jyh-Cherng Yu^e ; Alice L. Yu^a ; ^c ; ^f ; ^{ayu@gate.sinica.edu.tw" class="auth_mail" title="E-mail the corresponding author} ; John Yu^a ; ^b ; ^{csctcr.john@cgmh.org.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：HotLig ; GRP78 ; Cancer-targeting peptide ; Cancer stem cells ; Tumor imaging ; Drug delivery

刊名：Biomaterials

出版年：2016

5.The triterpene echinocystic acid and its 3-O-glucoside derivative are revealed as potent and selective glucocorticoid receptor agonists

作者：Demetra Georgatza^a ; ¹ ; Vyron A. Gorgogietas^a ; ¹ ; Paraskevi Kylindri^a ; Maria Ch. Charalambous^a ; Kalliope K. Papadopoulou^a ; Joseph M. Hayes^b ; Anna-Maria G. Psarra^a ; ^{ampsarra@bio.uth.gr" class="auth_mail" title="E-mail the corresponding author} ; ^{ampsarra@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：GCs ; glucocorticoids ; GR ; glucocorticoid receptor ; SEGRA ; selective glucocorticoid receptor agonist ; EA ; echinocystic acid ; EA-3G ; echinocystic acid 3-O-glucoside ; PEPCK ; phosphoenolpyruvate carboxykinase ; NF-κB ; nuclear factor kappa beta ; TNF α ; tumour necrosis factor alpha ; CMX ; mito tracker red CMXRos ; DEX ; dexamethasone ; DAC ; deacylcortivazol ; GREs ; glucocorticoid responsive elements ; LBD ; ligand binding domain ; HPA ; hypothalamic&ndash ; pituitary&ndash ; adrenal ; RLU ; relative luciferase units

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

6.Mechanisms of xenobiotic receptor activation: Direct vs. indirect

作者：Bryan Mackowiak ; Hongbing Wang ; ^{hwang@rx.umaryland.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AhR ; aryl hydrocarbon receptor ; ARNT ; aryl hydrocarbon nuclear translocator ; CAR ; constitutive androstane receptor ; CCRP ; cytoplasmic retention protein ; CITCO ; 6-(4-chlorophenyl)imidazo [2 ; 1-beta][1 ; 3]thiazole-5-carbaldehyde-O-(3 ; 4-dichlorobenzyl)oxime ; DBD ; DNA-binding domain ; EGFR ; epidermal growth factor receptor ; ERK ; extracellular signal-regulated kinase ; FRET ; fluorescence resonance energy transfer ; GRIP1 ; glucocorticoid receptor interacting protein 1 ; HSP ; heat-shock protein ; LBD ; ligand-

刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

出版年：2016

7.Allosteric Regulation Points Control the Conformational Dynamics of the Molecular Chaperone Hsp90

作者：Alexandra Rehn¹ ; ^&dagger ; ; Elisabetta Moroni² ; ³ ; ^&dagger ; ; Bettina K. Zierer¹ ; Franziska Tippel¹ ; Giulia Morra² ; Christine John¹ ; Klaus Richter¹ ; Giorgio Colombo² ; ^{giorgio.colombo@icrm.cnr.it" class="auth_mail" title="E-mail the corresponding author} ; Johannes Buchner¹ ; ^{johannes.buchner@tum.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Hsp90 ; Heat shock protein 90 ; NTD ; N-terminal domain ; M-domain ; middle domain ; CTD ; C-terminal domain ; FRET ; Fö ; rster resonance energy transfer ; MD ; molecular dynamics ; LF ; local flexibility ; WT ; wild type ; GR ; glucocorticoid receptor ; GR-LBD ; GR ligand binding domain ; aUC ; analytical ultracentrifugation ; v-Src ; viral Src kinase

刊名：Journal of Molecular Biology

出版年：2016

8.Adhesion GPCRs in immunology

作者：Saskia Nijmeijer ; ^{s.nijmeijer@vu.nl" class="auth_mail" title="E-mail the corresponding author} ; Henry F. Vischer ^{h.f.vischer@vu.nl" class="auth_mail" title="E-mail the corresponding author} ; Rob Leurs ^{r.leurs@vu.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：GPCR ; G protein-coupled receptor ; aGPCR ; adhesion G protein-coupled receptor ; ADGR ; general adhesion GPCR name followed by class and subtype specific code ; 7TM ; 7 transmembrane ; VLGR1 ; very large G protein-coupled receptor 1 ; ECD ; extracellular domain ; GPS ; GPCR proteolysis site ; GAIN ; GPCR autoproteolysis inducing ; NTF ; N-terminal fragment ; CTF ; C-terminal fragment ; HBD ; hormone binding domain ; FLRT ; fibronectin leucine-rich repeat transmembrane ; EGF ; epidermal growth factor ; PTX ; pentraxin ; Ig

刊名：Biochemical Pharmacology

出版年：2016

9.Treatment of metastatic castration-resistant prostate cancer (mCRPC) with enzalutamide

作者：Giulia Baciarello ^{giulia.baciarello@gmail.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae ; Cora N. Sternberg ; ^{cnsternberg@corasternberg.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae

关键词：ADT ; androgen deprivation therapy ; AR ; androgen receptor ; AR-V ; androgen receptor splice variant ; AR-V7 ; androgen receptor splice variant 7 ; ASCO ; American Society of Clinical Oncology ; CRPC ; castration-resistant prostate cancer ; CTC ; circulating tumor cells ; GR ; glucocorticoid receptor ; HR ; hazard ratio ; HRQoL ; health-related quality of life ; LBD ; ligand-binding domain ; mCRPC ; metastatic castration-resistant prostate cancer ; OS ; overall survival ; PCWG2 ; Prostate Cancer Clinical Trials Working G

刊名：Critical Reviews in Oncology and Hematology

出版年：2016

10.Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation

作者：Vassilios Myrianthopoulos^a ; ^b ; ; Pierre Francois Cartron^c ; Zita Liutkevičiūtė^d ; Saulius Klima&scaron ; auskas^d ; Daumantas Matulis^e ; Christian Bronner^g ; Nadine Martinet^f ; Emmanuel Mikros^a ; ^{mikros@pharm.uoa.gr" class="auth_mail" title="E-mail the corresponding author}

关键词：Epigenetics ; Structure-based screening ; Ligand-based screening ; DNA demethylation ; Compound NSC232003 ; QM-docking

刊名：European Journal of Medicinal Chemistry

出版年：2016

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