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在“Elsevier电子期刊”中，命中：272条，耗时：小于0.01 秒

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1.Structural and biochemical characterization of GTP cyclohydrolase II from Helicobacter pylori reveals its redox dependent catalytic activity

作者：Savita Yadav ; Subramanian Karthikeyan ; ^{skarthik@imtech.res.in" class="auth_mail" title="E-mail the corresponding author}

关键词：DARP ; 2 ; 5-diamino-6-ribosylamino-4(3H)-pyrimidinone-5&prime ; -phosphate ; DTT ; dithiothreitol ; GCHI ; GTP cyclohydrolase I ; hGCHII ; GTP cyclohydrolase II from Helicobacter pylori ; GCHII ; GTP cyclohydrolase II ; GCHIII ; GTP cyclohydrolase III ; GMP ; guanosine monophosphate ; GMPCPP ; guanosine-5&prime ; -[(伪 ; 尾)-methyleno]-triphosphate ; GTP ; guanosine triphosphate ; MMTS ; S-methyl methanethiosulfonate ; H2O2 ; hydrogen peroxide ; PAR ; 4-(2-pyridylazo)resorcinol ; PISA ; Proteins ; Interfaces ; Structures and Assem

刊名：Journal of Structural Biology

出版年：2015

2.Liraglutide restores angiogenesis in palmitate-impaired human endothelial cells through PI3K/Akt-Foxo1-GTPCH1 pathway

作者：Jing Ke¹ ; Rui Wei¹ ; Fei Yu ; Jingjing Zhang ; Tianpei Hong ; ^{tpho66@bjmu.edu.cn}

关键词：DAHP ; 2 ; 4-diamino-6-hydroxypyrimidine ; DPP-4 ; dipeptidyl peptidase 4 ; eNOS ; endothelial nitric oxide synthase ; Foxo1 ; forkhead box O1 ; GLP-1 ; glucagon-like peptide-1 ; GTPCH1 ; guanosine 5&prime ; -triphosphate cyclohydrolase 1 ; HUVECs ; human umbilical vein endothelial cells ; L-NAME ; N-nitro-l-arginine-methyl ester ; NO ; nitric oxide ; NOS ; nitric oxide synthase ; PA ; palmitic acid ; TFP ; trifluoperazine dihydrochloride

刊名：Peptides

出版年：2016

3.2-Acetyl-7-hydroxy-6-methoxy-1-methyl-1,2,3,4,-tetrahydroisoquinoline exhibits anti-inflammatory properties and protects the nigral dopaminergic neurons

作者：Hyo Jin Son^a ; Se Hee Han^a ; Ji Ae Lee^a ; Cheol Soon Lee^b ; Jai Woong Seo^c ; Dae Yoon Chi^c ; ^d ; ^{dychi@sogang.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Onyou Hwang^a ; ^{oyhwang@amc.seoul.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：AMTIQ ; 2-acetyl-7-hydroxy-6-methoxy-1-methyl-1234 ; -tetarhydroisoquinoline ; BH4 ; tetrahydrobiopterin ; CYP ; cytochrome P450 ; DAergic ; dopaminergic ; ELISA ; enzyme-linked immuno sorbent assay ; GTPCH ; GTP cyclohydrolase I ; IL-1β ; interleukin-1β ; iNOS ; inducible NO synthase ; LPS ; lipopolysaccharide ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; NF-κB ; nuclear factor-κB ; NO ; nitric oxide ; PBS ; phosphate-buffered saline ; PD ; Parkinson&rsquo ; s disease ; PCR ; polymerase chain reaction ; RT ; reverse

刊名：European Journal of Pharmacology

出版年：2016

4.Metformin attenuates fluctuating glucose-induced endothelial dysfunction through enhancing GTPCH1-mediated eNOS recoupling and inhibiting NADPH oxidase

作者：Huijie An^a ; ^b ; ¹ ; Rui Wei^a ; ¹ ; Jing Ke^a ; Jin Yang^a ; Ye Liu^a ; Xian Wang^c ; Guang Wang^a ; ^b ; ^{drwg6688@126.com" class="auth_mail" title="E-mail the corresponding author} ; Tianpei Hong^a ; ^{tpho66@bjmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Fluctuating glucose ; Guanosine 5&prime ; -triphosphate cyclohydrolase 1 ; Human umbilical vein endothelial cells ; Metformin ; Type 2 diabetes

刊名：Journal of Diabetes and its Complications

出版年：2016

5.Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension

作者：Surawee Chuaiphichai^a ; ^b ; Anna Starr^c ; Manasi Nandi^c ; Keith M. Channon^a ; ^b ; Eileen McNeill^a ; ^b ; ^c ; ^{eileen.mcneill@well.ox.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：Gch1 ; GTP cyclohydrolase 1 ; BH4 ; tetrahydrobiopterin ; LPS ; lipopolysaccharide

刊名：Vascular Pharmacology

出版年：2016

6.Low frequency of GCH1 and TH mutations in Parkinson's disease

作者：Aina Rengmark^a ; Lasse Pihlstrø ; m^a ; ^b ; Jan Linder^c ; Lars Forsgren^c ; Mathias Toft^a ; ^{mathias.toft@medisin.uio.no" class="auth_mail" title="E-mail the corresponding author}

关键词：Parkinson's disease ; Dopa-responsive dystonia ; GTP-Cyclohydrolase 1 ; Tyrosine hydroxylase ; Mutation ; Sequencing

刊名：Parkinsonism & Related Disorders

出版年：2016

7.Increasing tetrahydrobiopterin in cardiomyocytes adversely affects cardiac redox state and mitochondrial function independently of changes in NO production

作者：Savitha Sethumadhavan^a ; Jennifer Whitsett^a ; Brian Bennett^a ; ^c ; Irina A. Ionova^b ; Galen M. Pieper^b ; Jeannette Vasquez-Vivar^a ;

关键词：7 ; 8-Dihydrobiopterin ; Biopterin ; Neopterin ; Electron paramagnetic resonance ; GTP cyclohydrolase I

刊名：Free Radical Biology and Medicine

出版年：2016

8.Tetrahydrobiopterin Role in human umbilical vein endothelial dysfunction in maternal supraphysiological hypercholesterolemia

作者：Andrea Leiva^a ; ^{aaleiva@uc.cl" class="auth_mail" title="E-mail the corresponding author} ; Bá ; rbara Fuenzalida^a ; Roc&iacute ; o Salsoso^a ; ^d ; Eric Barros^a ; Fernando Toledo^a ; ^b ; Jaime Gutié ; rrez^a ; ^c ; Fabiá ; n Pardo^a ; Luis Sobrevia^a ; ^d ; ^e ; ^{sobrevia@med.puc.cl" class="auth_mail" title="E-mail the corresponding author}

关键词：MPH ; maternal physiological hypercholesterolemia ; MSPH ; maternal supraphysiological hypercholesterolemia ; GTP ; guanosine triphosphate ; GTPCH1 ; GTP cyclohydrolase 1 ; DHFR ; dihydrofolate reductase ; BH2 ; dihydrobiopterine ; BH4 ; tetrahydrobiopterine ; HUVECs ; human umbilical vein endothelial cells ; TCh ; total cholesterol ; LDL ; low density lipoprotein ; vLDL ; very-low density lipoprotein ; HDL ; high-density lipoprotein ; NO ; nitric oxide ; eNOS ; endothelial nitric oxide synthase ; CGRP ; calcitonine gene re

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2016

9.Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I

作者：Anantha Vijay R. Santhanam ; Livius V. d&rsquo ; Uscio ; Zvonimir S. Katusic ; ^{katusic.zvonimir@mayo.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Tetrahydrobiopterin ; Endothelial nitric oxide synthase ; GTP-cyclohydrolase I ; Cerebral microvessel

刊名：Brain Research

出版年：2015

10.The International Working Group on Neurotransmitter related Disorders (iNTD): A worldwide research project focused on primary and secondary neurotransmitter disorders

作者：Thomas Opladen^a ; ^{Thomas.opladen@med.uni-heidelberg.de} ; Elisenda Cortè ; s-Saladelafont^b ; Mario Mastrangelo^c ; Gabriella Horvath^d ; Roser Pons^e ; Eduardo Lopez-Laso^f ; Joaqu&iacute ; n A. Ferná ; ndez-Ramos^f ; Tomas Honzik^g ; Toni Pearson^h ; Jennifer Friedmanⁱ ; Sabine Scholl-Bü ; rgi^j ; Tessa Wassenberg^k ; Sabine Jung-Klawitter^a ; Oya Kuseyri^a ; Kathrin Jeltsch^a ; Manju A. Kurian^l ; À ; ngels Garcia-Cazorla^b ; on behalf of the International Working Group on Neurotransmitter related disorders (iNTD)

关键词：AADC ; aromatic l-amino acid decarboxylase ; AR/ADGTPCH ; autosomal recessive/dominant GTP-cyclohydrolase deficiency ; BH4 ; tetrahydrobiopterin ; DAT ; dopamine transporter ; D&szligH ; dopamine β-hydroxylase ; DHFR ; dihydrofolate reductase deficiency ; DHPR ; dihydropteridine reductase ; FOLR1 ; folate receptor alpha ; GABA ; gamma aminobutyric acid ; MAOA ; monoamine oxidase A ; 5-MTHF ; 5-methyltetrahydrofolate ; NKH ; nonketotic hyperglycinemia ; NOS ; nitric oxide synthase ; PAH ; phenylalanine hydroxylase ; 3-PGDH

刊名：Molecular Genetics and Metabolism Reports

出版年：2016

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