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Elsevier电子期刊(282)

在“Elsevier电子期刊”中，命中：282条，耗时：0.0679789 秒

在所有数据库中总计命中：403条

1.An investigation into the formation of tebufenozide's toxic aromatic amine metabolites in human in vitro hepatic microsomes

作者：Khaled M. Abass¹ ; ^{khaled.m.abass@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; ^{khaled.megahed@oulu.fi" class="auth_mail" title="E-mail the corresponding author}

关键词：Insect growth regulators ; Pesticides ; In vitro biotransformation ; Human hepatic microsomes ; Methemoglobinemia

刊名：Pesticide Biochemistry and Physiology

出版年：2016

2.In vitro metabolism of l-corydalmine, a potent analgesic drug, in human, cynomolgus monkey, beagle dog, rat and mouse liver microsomes

作者：Xiange Tang ; Xinyu Di ; Zeyu Zhong ; Qiushi Xie ; Yang Chen ; Fan Wang ; Zhaoli Ling ; Ping Xu ; Kaijing Zhao ; Zhongjian Wang ; Li Liu ; ^{liulee@cpu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Xiaodong Liu ; ^{xdliu@cpu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：l-Corydalmine ; Metabolism ; Hepatic microsomes ; Cytochrome P450s ; Interspecies difference

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2016

3.In vitro effects of the citrus flavonoids diosmin, naringenin and naringin on the hepatic drug-metabolizing CYP3A enzyme in human, pig, mouse and fish

作者：Viktoriia Burkina^a ; ^{vburkina@frov.jcu.cz" class="auth_mail" title="E-mail the corresponding author} ; Vladimir Zlabek^a ; ^{vzlabek@frov.jcu.cz" class="auth_mail" title="E-mail the corresponding author} ; Ruth Halsne^b ; ^{ruth.halsne@nmbu.no" class="auth_mail" title="E-mail the corresponding author} ; Erik Ropstad^b ; ^{erik.ropstad@nmbu.no" class="auth_mail" title="E-mail the corresponding author} ; Galia Zamaratskaia^a ; ^c ; ^{Galia.Zamaratskaia@slu.se" class="auth_mail" title="E-mail the corresponding author}

关键词：Diosmin (PubChem CID ; 5353588) ; Naringin (PubChem CID ; 25075) ; Naringenin (PubChem CID ; 932)

刊名：Biochemical Pharmacology

出版年：2016

4.QSARs for estimating intrinsic hepatic clearance of organic chemicals in humans

作者：Alessandra Pirovano^a ; ^{a.pirovano@science.ru.nl" class="auth_mail" title="E-mail the corresponding author} ; Stefan Brandmaier^b ; Mark A.J. Huijbregts^a ; Ad M.J. Ragas^a ; ^c ; Karin Veltman^d ; A. Jan Hendriks^a

关键词：Quantitative structure&ndash ; activity relationship ; Biotransformation ; Clearance (CLINT) ; Hepatocytes ; Microsomes

刊名：Environmental Toxicology and Pharmacology

出版年：2016

5.Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7

作者：Roope A. Kallionpä ; ä ; ¹ ; Erkka Jä ; rvinen ; Moshe Finel ; ^{moshe.finel@helsinki.fi" class="auth_mail" title="E-mail the corresponding author}

关键词：16α-OHE1 ; 16α-hydroxyestrone ; E1 ; estrone ; E2 ; 17β-estradiol ; HIM ; human intestine microsomes ; HLM ; human liver microsomes ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid ; UGT ; UDP-glucuronosyltransferase

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2015

6.Meclizine, a pregnane X receptor agonist, is a direct inhibitor and mechanism-based inactivator of human cytochrome P450 3A

作者：Winnie Yin Bing Foo^a ; ^{winnie_foo@u.nus.edu" class="auth_mail" title="E-mail the corresponding author} ; Hwee Ying Tay^a ; ^{a0083608@u.nus.edu" class="auth_mail" title="E-mail the corresponding author} ; Eric Chun Yong Chan^a ; ^{phaccye@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author} ; Aik Jiang Lau^a ; ^b ; ^{aikjiang.lau@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author}

关键词：Meclizine dihydrochloride monohydrate (PubChem CID ; 173612) ; Norchlorcyclizine (PubChem CID ; 9340) ; 6尾-Hydroxytestosterone (PubChem CID ; 65543) ; Testosterone (PubChem CID ; 6013) ; Prednisolone (PubChem CID ; 5755) ; Ketoconazole (PubChem CID ; 456201) ; Erythromycin (PubChem CID ; 12560) ; Glutathione (PubChem CID ; 124886) ; N-acetylcysteine (PubChem CID ; 12035)

刊名：Biochemical Pharmacology

出版年：2015

7.Ginsenoside-mediated blockade of 1伪,25-dihydroxyvitamin D₃ inactivation in human liver and intestine in vitro

作者：Subrata Deb ; Mei Yieng Chin ; Hans Adomat ; Emma S. Tomlinson Guns ; ^{eguns@prostatecentre.com" class="auth_mail}

关键词：1伪 ; 25(OH)2D3 ; 1伪 ; 25-dihydroxyvitamin D3 ; aPPD ; 20(S)-protopanaxadiol ; aPPT ; 20(S)-protopanaxatriol ; CYP ; cytochrome P450 ; VDR ; vitamin D receptor ; LC&ndash ; MS/MS ; liquid chromatography&ndash ; tandem mass spectrometry ; HLM ; human liver microsomes ; HIM ; human intestinal microsomes ; rCYP3A4 ; recombinant cytochrome P450 3A4 ; UGT ; UDP-glucuronosyltransferases

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：May, 2014

8.Effect of uremic serum and uremic toxins on drug metabolism in human microsomes

作者：Donna A. Volpe ; Grainne A. Tobin ; Fatemeh Tavakkoli ; Thomas C. Dowling ; Paul D. Light ; Robert J. Parker

关键词：AUC ; area under the plasma concentration curve ; Cmax ; maximal plasma concentration ; CMPF ; 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid ; CRF ; chronic renal failure ; CYP ; cytochrome P450 ; ESRD ; end-stage renal disease ; HLM ; human liver microsome ; IC50 ; concentration that results in 50% inhibition ; LC/MS&ndash ; MS ; liquid chromatography tandem mass spectroscopy ; MRM ; multiple reaction monitoring ; NADP ; 尾-nicotinamide adenine dinucleotide phosphate sodium salt hydrate ; NRS ; NADP regenerating so

刊名：Regulatory Toxicology and Pharmacology

出版年：March, 2014

9.Marsdenia tenacissima extract inhibits gefitinib metabolism in vitro by interfering with human hepatic CYP3A4 and CYP2D6 enzymes

作者：Shu-Yan Han ; Hai-Yu Zhao ; Ning Zhou ; Fei Zhou ; Ping-Ping Li

关键词：Marsdenia tenacissima extract (Xiao-Ai-Ping injection) ; Gefitinib ; Cytochrome P450 ; Drug metabolism

刊名：Journal of Ethnopharmacology

出版年：10 January, 2014

10.Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry

作者：Wang-Hui Jing^a ; Yue-Lin Song^a ; Ru Yan^a ; ^{ruyan@umac.mo} ; Yi-Tao Wang^a ; ^b

关键词：Angular-type pyranocoumarins ; (+)-Praeruptorin A ; UHPLC&ndash ; QT-MS/MS ; Human liver microsomes ; CYP 3A4

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2013

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