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1.ST2 from rainbow trout quenches TLR signalling, localises at the nuclear membrane and allows the nuclear translocation of MYD88

作者：Alexander Rebl^a ; Henrike Rebl^b ; Judith M. Kö ; bis^a ; Tom Goldammer^a ; Hans-Martin Seyfert^a ; ^{seyfert@fbn-dummerstorf.de}

关键词：CHSE-214 ; Evolution ; HEK-293 ; Interleukin 1 receptor-like 1 ; Oncorhynchus mykiss ; Toll-like receptor signalling ; TIR-domain

刊名：Developmental & Comparative Immunology

出版年：2017

2.Porphyromonas gingivalis-stimulated macrophage subsets exhibit differential induction and responsiveness to interleukin-10

作者：Andrew D. Foey^a ; ^{andrew.foey@plymouth.ac.uk} ; Neama Habil^a ; Khalid Al-Shaghdali^a ; StJohn Crean^b

关键词：Mϕs ; macrophages ; IL-10 ; interleukin-10 ; IL-10R ; interleukin-10 Receptor ; TNFα ; tumour necrosis factor-α ; CP ; chronic periodontitis ; PG-LPS ; porphyromonas gingivalis lipopolysaccharide ; TLR ; toll-like receptor ; ET ; endotoxin tolerance ; STAT-3 ; signal transducer and activation of transcription-3 ; NFκB ; nuclear factor-kappa B ; SOCS-3 ; suppressor of cytokine signalling-3 ; PAMPs ; pathogen associated molecular patterns

刊名：Archives of Oral Biology

出版年：2017

3.Cigarette smoke extracts induce overexpression of the proto-oncogenic gene interleukin-13 receptor α2 through activation of the PKA-CREB signaling pathway to trigger malignant transformation of lung vascular endothelial cells and angiogenesis

作者：Mei Meng¹ ; Huaidong Liao¹ ; Bin Zhang¹ ; Yanyan Pan ; Ying Kong ; Wenming Liu ; Ping Yang ; Zihe Huo ; Zhifei Cao ; Quansheng Zhou ; ^{zhouqs@suda.edu.cn}

关键词：Lung cancer ; Cigarette smoke extract ; Angiogenesis ; Tumor-associated endothelial cells ; IL-13Rα2 ; CT-19

刊名：Cellular Signalling

出版年：2017

4.From bones to blood pressure, developing novel biologic approaches targeting the osteoprotegein pathway for pulmonary vascular disease

作者：Sarah Dawson ; Allan Lawrie ; ^{a.lawrie@sheffield.ac.uk}

关键词：5HT ; 5 hydroxytriptamine ; Apo2L ; Apoprotein 2 ligand ; ApoE ; Apolipoprotein E ; BMPR2 ; Bone morphogenetic protein receptor type 2 ; CAD ; Coronary artery disease ; CKD ; Chronic kidney disease ; DR4/5 ; Death receptor 4/5 ; DcR1/2 ; Decoy receptor 1/2 ; FGF-2 ; Fibroblast growth factor 2 ; HuDEMC ; Human dermal microvascular endothelial cells ; HMVEC ; Human microvascular endothelial cells ; HUVEC ; Human umbilical cord vein endothelial cells ; IL-1 ; Interleukin 1 ; kDa ; Kilodalton ; LDLR ; Low-density lipoprotein re

刊名：Pharmacology & Therapeutics

出版年：2017

5.Hyaluronan carried by tumor-derived microvesicles induces IL-10 production in classical (CD14⁺⁺CD16⁻) monocytes via PI3K/Akt/mTOR-dependent signalling pathway

作者：Marzena Lenart^a ; Magdalena Rutkowska-Zapala^a ; Monika Baj-Krzyworzeka^a ; Rafał Szatanek^a ; Kazimierz Węglarczyk^a ; Timothy Smallie^b ; Lö ; ms Ziegler-Heitbrock^c ; ^d ; Marek Zembala^a ; Maciej Siedlar^a ; ^{misiedla@cyf-kr.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：DCs ; dendritic cells ; HA ; hyaluronan ; IRF ; interferon regulatory factor ; MOI ; multiplicity of infection ; PKB ; protein kinase B ; RNI ; reactive nitrogen intermediates ; ROI ; reactive oxygen species ; mTOR ; mammalian target of rapamycin ; TIM ; tumor-infiltrating monocytes/macrophages ; TMV ; tumor microvesicles

刊名：Immunobiology

出版年：2017

6.Rho-kinase inhibitor treatment prevents pulmonary inflammation and coagulation in lipopolysaccharide-induced lung injury

作者：Renyu Ding ; ^{renyuding@126.com} ; Dongmei Zhao ; Xiaoxia Li ; Baoyan Liu ; Xiaochun Ma ; ^{xcma2972@sina.com}

关键词：Acute lung injury ; (ALI) ; Lipopolysaccharide ; (LPS) ; Human pulmonary microvascular endothelial cells ; (HPMECs) ; Myeloperoxidase ; (MPO) ; Interleukins 1-beta ; (IL-1β) ; Interluekin-6 ; (IL-6) ; Nuclear factor ; ((NF)-κB.) ; Tumor necrosis factor ; (TNF)-α ; Tissue factor ; (TF) ; Plasminogen activator inhibitors ; (PAIs) ; Bronchoalveolar lavage fluid ; (BALF) ; Enzyme-linked immunosorbent assay ; (ELISA) ; Radioimmunoprecipitation assay ; (RIPA) ; Real-time polymerase chain reaction ; (qPCR) ; Dimethylarginine dime

刊名：Thrombosis Research

出版年：2017

7.The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair

作者：Divya Ramnath^a ; ^b ; ^c ; Elizabeth E. Powell^d ; ^e ; Glen M. Scholz^f ; ^g ; Matthew J. Sweet^a ; ^b ; ^c ; ^{m.sweet@imb.uq.edu.au}

关键词：BBB ; blood brain barrier ; Bcl2 ; B-cell CLL/lymphoma 2 ; CNS ; Central nervous system ; CXCL ; C-X-C motif ligand ; EBI3 ; Epstein-Barr virus induced gene 3 ; FADD ; Fas-associated death domain ; HBV ; Hepatitis B virus ; HSC ; Hepatic stellate cell ; HSV ; Herpes simplex virus ; I/R ; Ischemia reperfusion ; IAV ; Influenza A virus ; IEC ; Intestinal epithelial cell ; IFN ; Interferon ; IL ; Interleukin ; IRF ; Interferon regulatory factor ; MAL ; MyD88 adaptor-like ; MAPK ; Mitogen-activated protein kinase ; MyD88 ; Myeloid di

刊名：Seminars in Cell & Developmental Biology

出版年：2017

8.Wounds that heal and wounds that don’t − The role of the IL-33/ST2 pathway in tissue repair and tumorigenesis

作者：Neal L. Millar^a ; Charlotte O&rsquo ; Donnell^b ; Iain B. McInnes^a ; Elizabeth Brint^b ; ^c ; ^{e.brint@ucc.ie}

关键词：Interleukin 33 ; ST2 ; Tissue damage ; Fibrosis ; Tumorigenesis

刊名：Seminars in Cell & Developmental Biology

出版年：2017

9.Genomic and genetic studies of systemic sclerosis: A systematic review

作者：Paraskevi Chairta ; Paschalis Nicolaou ; Kyproula Christodoulou ; ^{roula@cing.ac.cy}

关键词：ACA ; anti-centromere antibody ; AID ; autoimmune disease ; ARA ; anti-RNA polymerase III antibody ; ATA ; anti-topoisomerase I antibody ; SSc ; systemic sclerosis ; dcSSc ; diffused cutaneous SSc ; lcSSc ; limited cutaneous SSc ; GWAS ; Genome Wide Association Study ; HLA ; human leukocyte antigen ; MHC ; major histocompatibility complex ; PAH ; pulmonary arterial hypertension ; RA ; rheumatoid arthritis ; SLE ; systemic lupus erythematosus ; VNTRs ; variable number tandem repeats

刊名：Human Immunology

出版年：2017

10.Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-inhibitor REDD1 in a STAT3-dependent manner

作者：Jessica Pinno^a ; ^{jessica.pinno@st.ovgu.de" class="auth_mail" title="E-mail the corresponding author} ; Hannes Bongartz^a ; ^{hannes.bongartz@ovgu.de" class="auth_mail" title="E-mail the corresponding author} ; Oliver Klepsch^a ; ^{oliver.klepsch@ovgu.de" class="auth_mail" title="E-mail the corresponding author} ; Nicole Wundrack^a ; ^{nicole.wundrack@ovgu.de" class="auth_mail" title="E-mail the corresponding author} ; Valeria Poli^b ; ^{valeria.poli@unito.it" class="auth_mail" title="E-mail the corresponding author} ; Fred Schaper^a ; ^{fred.Schaper@ovgu.de" class="auth_mail" title="E-mail the corresponding author} ; Anna Dittrich^a ; ^{anna.dittrich@ovgu.de" class="auth_mail" title="E-mail the corresponding author}

关键词：HIF ; Hypoxia-inducible Factor ; IL-6 ; Interleukin 6 ; IRS1 ; Insulin Receptor Substrate 1 ; Jak ; Januskinase ; mTOR ; Mammalian Target of Rapamycin ; MEF ; Mouse Embryonic Fibroblast ; NF-κB ; Nuclear Factor kappa B ; n.s. ; non-significant ; MAPK ; Mitogen-Activated Protein Kinase ; OSM ; Oncostatin M ; P70 S6K ; P70 S6 kinase ; PI3K ; Phosphatidylinositide-3-kinase ; PP2A ; Protein Phosphatase 2A ; PDTC ; Pyrrolidine Dithiocarbamate ; RHEB ; Ras Homolog Enriched in Brain ; REDD1 ; Regulated in Development and DNA Damage

刊名：Cellular Signalling

出版年：2016

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