作者：Nicolas Newell ; ^{n.newell09@imperial.ac.uk} ; Grigorios Grigoriadis ; Alexandros Christou ; Diagarajen Carpanen ; Spyros D. Masouros

关键词：Intervertebral disc ; spine ; Finite element modelling ; inverse methods ; Collagen fibre ; material properties

刊名：Journal of the Mechanical Behavior of Biomedical Materials

出版年：2017

作者：Gregory D. Schroeder ; MD^a ; ^b ; ¹ ; ^{gregdschroeder@gmail.com} ; Dessislava Z. Markova ; PhD^b ; ¹ ; John D. Koerner ; MD^a ; ^b ; Jeffery A. Rihn ; MD^a ; ^b ; Alan S. Hilibrand ; MD^a ; ^b ; Alexander R. Vaccaro ; MD ; PhD ; MBA^a ; ^b ; D. Greg Anderson ; MD^a ; ^b ; Christopher K. Kepler ; MD ; MBA^a ; ^b

关键词：Cytokines ; Degenerative discs ; Intervertebral disc ; Low back pain ; Lumbar spine ; Modic changes

刊名：The Spine Journal

出版年：2017

作者：Chencheng Feng¹ ; ^{doctorfgy@163.com} ; Yang Zhang¹ ; ^{65210796@qq.com} ; Minghui Yang¹ ; ^{doc_ymh@163.com} ; Minghong Lan¹ ; ^{fccdoc@me.com} ; Huan Liu¹ ; ^{20016040@163.com} ; Jian Wang¹ ; ^{tonywjxq@aliyun.com} ; Yue Zhou ; ¹ ; ^{happyzhou@vip.163.com} ; Bo Huang ; ¹ ; ^{fmmuhb@126.com}

关键词：IVD ; intervertebral disc ; IDD ; intervertebral disc degeneration ; SASP ; senescence-associated secreted phenotype ; NP ; nucleus pulposus ; AF ; annulus fibrosus ; SA-β-Gal ; senescence-associated β-galactosidase ; ECM ; extracellular matrix ; DDR ; DNA damage response ; N-Ac-PGP ; N-acetylated proline-glycine-proline ; RS ; replicative senescence ; Rb ; retinoblastoma protein ; RPX ; Reparixin ; ADAMTS ; a disintegrin and metalloproteinase with thrombospondin motifs ; MMP ; matrix metalloproteinase ; PE ; prolyl endopep

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

作者：C. Schleich^&dagger ; ; ^{christoph.schleich@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; A. Mü ; ller-Lutz^&dagger ; ; ^{anja.lutz@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; K. Blum^&dagger ; ; ^{katrin.blum@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; J. Boos^&dagger ; ; ^{johannes.boos@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; B. Bittersohl^&Dagger ; ; ^{bernd.bittersohl@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; B. Schmitt^§ ; ; ^{benjamin_schmitt@siemens.com" class="auth_mail" title="E-mail the corresponding author} ; J. Gerß ; ​^{‖ ; joachim.gerss@ukmuenster.de" class="auth_mail" title="E-mail the corresponding author} ; F. Matuschke^&dagger ; ; ^{felix.matuschke@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; H.-J. Wittsack^&dagger ; ; ^{wittsack@uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; G. Antoch^&dagger ; ; ^{gabriele.bester@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; F. Miese^&dagger ; ; ^{falkmiese@gmx.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Glycosaminoglycan chemical exchange saturation transfer ; Facet tropism ; Facet orientation ; Intervertebral discs ; MRI

刊名：Osteoarthritis and Cartilage

出版年：2016

作者：Qiaoqiao Zhu^a ; Xin Gao^b ; Na Li^b ; Weiyong Gu^a ; ^b ; ^{wgu@miami.edu" class="auth_mail" title="E-mail the corresponding author} ; Frank Eismont^c ; Mark D. Brown^c

关键词：Intervertebral disc ; Antibiotic penetration ; Transport phenomena ; Mixture theory ; Finite element analysis ; Disc infections

刊名：Journal of Biomechanics

出版年：2016

作者：A. Yee^&dagger ; ; M.P.Y. Lam^&Dagger ; ; V. Tam^&dagger ; ; W.C.W. Chan^&dagger ; ; I.K. Chu^&Dagger ; ; K.S.E. Cheah^&dagger ; ; K.M.C. Cheung^§ ; ; ^{cheungmc@hku.hk" class="auth_mail" title="E-mail the corresponding author} ; D. Chan^&dagger ; ; ^{chand@hku.hk" class="auth_mail" title="E-mail the corresponding author}

关键词：Intervertebral disc ; Disc degeneration ; Fibrosis ; Proteome ; Mass spectrometry ; Quantitative method

刊名：Osteoarthritis and Cartilage

出版年：2016

作者：Anja Mü ; ller-Lutz^a ; Christoph Schleich^a ; ^{Christoph.Schleich@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author} ; Benjamin Schmitt^b ; Gerald Antoch^a ; Felix Matuschke^a ; Michael Quentin^a ; Hans-Jö ; rg Wittsack^a ; Falk Miese^a

关键词：Chemical exchange saturation transfer (CEST) ; Glycosaminoglycan content ; Intervertebral disc ; Gender ; Body mass index ; T2 value

刊名：Magnetic Resonance Imaging

出版年：2016

作者：F.-J. Lv^&dagger ; ; ^&Dagger ; ; ^§ ; ; ^‖ ; ^{fengjuan@hku.hk" class="auth_mail" title="E-mail the corresponding author} ; ^{fengjuan.lv@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Y. Peng^&dagger ; ; ^{u3002479@connect.hku.hk" class="auth_mail" title="E-mail the corresponding author} ; F.L. Lim^&dagger ; ; ^{h0894164@connect.hku.hk" class="auth_mail" title="E-mail the corresponding author} ; Y. Sun^&dagger ; ; ^‖ ; ^{hkusunyi@connect.hku.hk" class="auth_mail" title="E-mail the corresponding author} ; M. Lv^¶ ; ; ^{lvminmin2015@163.com" class="auth_mail" title="E-mail the corresponding author} ; L. Zhou^&dagger ; ; ^{lxzhou@connect.hku.hk" class="auth_mail" title="E-mail the corresponding author} ; H. Wang^# ; ^{wangxucheng@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Z. Zheng^# ; ^{zhengzm1@163.com" class="auth_mail" title="E-mail the corresponding author} ; K.M.C. Cheung^&dagger ; ; ^§ ; ; ^‖ ; ^{ken-cheung@hku.hk" class="auth_mail" title="E-mail the corresponding author} ; V.Y.L. Leung^&dagger ; ; ^&Dagger ; ; ^§ ; ; ^‖ ; ^{vicleung@hku.hk" class="auth_mail" title="E-mail the corresponding author}

关键词：Intervertebral disc ; Degeneration ; Nucleus pulposus ; Matrix metalloproteinase ; MMP12 ; Myofibroblast

刊名：Osteoarthritis and Cartilage

出版年：2016

作者：Yi Feng^a ; Brian Egan^a ; Jinxi Wang^a ; ^b ; ^{jwang@kumc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Genetic factor ; Intervertebral disc ; Intervertebral disc degeneration ; Low back pain ; Polymorphism

刊名：Genes & Diseases

出版年：2016

作者：Pablo Andrade ; MD ; PhD^a ; ^b ; ^c ; ^{pablo.andrade-montemayor@uk-koeln.de" class="auth_mail" title="E-mail the corresponding author} ; Govert Hoogland ; PhD^a ; ^b ; Onno P. Teernstra ; MD ; PhD^a ; Jasper van Aalst ; MD ; PhD^a ; Emiel van Maren ; MD^a ; Marc A. Daemen ; MD ; PhD^d ; Veerle Visser-Vandewalle ; MD ; PhD^a ; ^e

关键词：Discectomy ; Intervertebral disc ; Lumbar disc herniation ; Sciatica ; TNF-α ; Neuroinflammation ; Chronic pain ; Pain ; TNF-α receptors ; Leg pain

刊名：The Spine Journal

出版年：2016