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Wiley电子期刊(38)	ProQuest学位论文(2)	Elsevier电子期刊(491)
SpringerLink电子期刊(123)	NATURE电子期刊(3)	ACS电子期刊(305)

在“Elsevier电子期刊”中，命中：491条，耗时：小于0.01 秒

在所有数据库中总计命中：962条

1.An alkaloid-like 3-azabicyclo[3.3.1]non-3-ene library obtained from the bridged Ritter reaction

作者：Steven G. Williams^a ; ^{Steven.Williams@uts.edu.au} ; Mohan Bhadbhade^b ; Roger Bishop^c ; Alison T. Ung^a

关键词：Bridged Ritter reaction ; Alkaloid-like ; 3-Aza-bicyclo[3.3.1]nonane ; Drug discovery

刊名：Tetrahedron

出版年：2017

2.Fragment library design, synthesis and expansion: nurturing a synthesis and training platform

作者：Peter C. RayAuthor Vitae ; Michael Kiczun ; Margaret Huggett ; Andrew Lim ; Federica Prati ; Ian H. Gilbert ; ^{i.h.gilbert@dundee.ac.uk}Author Vitae ; Paul G. Wyatt ; ^{p.g.wyatt@dundee.ac.uk}Author Vitae

刊名：Drug Discovery Today

出版年：2017

3.Piperlongumine derived cyclic sulfonamides (sultams): Synthesis and in vitro exploration for therapeutic potential against HeLa cancer cell lines

作者：Nitin P. Lad^a ; ^b ; Sarang Kulkarni^b ; Rajiv Sharma^b ; Malcolm Mascarenhas^b ; Mahesh R. Kulkarni^a ; ^b ; Shivaji S. Pandit^a ; ^{akankshapandit2002@yahoo.com}

关键词：Piperlongumine (PL) derived cyclic sulfonamide (sultams) ; Ring closing metathesis ; Anticancer ; GI50 values

刊名：European Journal of Medicinal Chemistry

出版年：2017

4.Discovery and evaluation of inhibitors to the immunosuppressive enzyme indoleamine 2,3-dioxygenase 1 (IDO1): Probing the active site-inhibitor interactions

作者：Petr Tomek^a ; Brian D. Palmer^a ; Jack U. Flanagan^a ; Chuanwen Sun^a ; ¹ ; Emma L. Raven^b ; Lai-Ming Ching^a ; ^{l.ching@auckland.ac.nz}

关键词：IDO ; Indoleamine 2 ; 3-dioxygenase ; Molecular modeling ; Drug screening ; Inhibitors ; Mutagenesis

刊名：European Journal of Medicinal Chemistry

出版年：2017

5.Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening

作者：Finith E. Jernigan^a ; ¹ ; Jun-ichi Hanai^b ; ^c ; Vikas P. Sukhatme^b ; ^c ; ^d ; Lijun Sun^a ; ^{lsun1@bidmc.harvard.edu}

关键词：Virtual screening ; Furoic acid ; ATP citrate lyase inhibitor ; Cancer metabolism ; Cancer stemness

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

6.Identification and validation of small molecule modulators of the NusB-NusE interaction

作者：Peter J. Cossar^a ; ³ ; Cong Ma^b ; ² ; ³ ; Christopher P. Gordon^a ; ¹ ; Joseph I. Ambrus^a ; Peter J. Lewis^b ; Adam McCluskey^a ; ^{Adam.McCluskey@newcastle.edu.au}

关键词：Protein-protein interaction ; NusB-NusE ; Antibiotic ; Pharmacophore ; In silico screening

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

7.Expedient synthesis of an atypical oxazolidinone compound library

作者：Sarah J. Cully^a ; Thomas E. Storr^a ; Michael J. Rawling^a ; Induka R. Abeysena^b ; Daniel Hamza^c ; Geraint Jones^c ; Christopher A. Pearce^c ; Abdul Quddus^c ; William Lewis^d ; Robert A. Stockman^a ;

关键词：sp3-rich ; Library ; Bicyclic ; Scaffold ; Oxazolidinone

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

8.Synthesis of two chiral octahydroindole scaffolds for drug discovery

作者：Magne O. Sydnes^a ; ^&dagger ; ; Phuc Van Le^a ; Jens Olschimke^a ; Peter C. Healy^b ; Agatha Garavelas^a ; Fatemeh Mazraati Tajabadi^a ; Liliana Pedro^a ; Ronald J. Quinn^a ; Ian D. Jenkins^a ; ^{i.jenkins@griffith.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Natural-product ; Scaffold ; Drug-discovery ; Synthesis ; Octahydroindole

刊名：Tetrahedron

出版年：2016

9.Combining microCT-based characterization with empirical modelling as a robust screening approach for the design of optimized CaP-containing scaffolds for progenitor cell-mediated bone formation

作者：G. Kerckhofs^a ; ^b ; ^{greet.kerckhofs@med.kuleuven.be" class="auth_mail" title="E-mail the corresponding author} ; Y.C. Chai^a ; ^b ; ¹ ; ^{yoke.chin.chai@vub.ac.be" class="auth_mail" title="E-mail the corresponding author} ; F.P. Luyten^a ; ^b ; ^{frank.luyten@uz.kuleuven.be" class="auth_mail" title="E-mail the corresponding author} ; L. Geris^a ; ^c ; ^d ; ^{liesbet.geris@ulg.ac.be" class="auth_mail" title="E-mail the corresponding author}

关键词：Optimized calcium phosphate-based constructs ; MicroCT characterization ; Empirical modelling ; Robust screening

刊名：Acta Biomaterialia

出版年：2016

10.Identification of B. anthracis N⁵-carboxyaminoimidazole ribonucleotide mutase (PurE) active site binding compounds via fragment library screening

作者：Hao Lei^a ; Christopher Jones^a ; Tian Zhu^a ; Kavankumar Patel^a ; Nina M. Wolf^b ; Leslie W.-M. Fung^b ; Hyun Lee^a ; ^{danielhl@uic.edu" class="auth_mail" title="E-mail the corresponding author} ; Michael E. Johnson^a ; ^{mjohnson@uic.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：PurE ; N5-carboxyaminoimidazole ribonucleotide mutase ; FBDD ; fragment-based drug design ; NMR ; nuclear magnetic resonance ; STD-NMR ; saturation transfer difference nuclear magnetic resonance (NMR) ; WaterLOGSY NMR ; water ligand observed via gradient spectroscopy NMR ; SPR ; surface plasmon resonance ; TSA ; thermal shift assay ; N5-CAIR ; N5-carboxyaminoimidazole ribonucleotide ; CAIR ; 4-carboxyaminoimidazole ribonucleotide ; AIR ; aminoimidazole ribonucleotide

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

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