搜索页_ MPP+ (1-methyl-4-phenylpyridinium)

常用资源

电子图书

期刊论文

学位会议

外文资源

特色专题

内部出版物

Wiley电子期刊(2)

SpringerLink电子期刊(147)

Elsevier电子期刊(454)

ACS电子期刊(13)

在“Elsevier电子期刊”中，命中：454条，耗时：0.0119893 秒

在所有数据库中总计命中：616条

1.Resveratrol attenuates MPP⁺-induced mitochondrial dysfunction and cell apoptosis via AKT/GSK-3β pathway in SN4741 cells

作者：Weijun Zeng^a ; ¹ ; Wei Zhang^b ; ^c ; ¹ ; Fangfang Lu^a ; Li Gao^a ; Guodong Gao^a ; ^{gaogd1954@163.com}

关键词：Res ; Resveratrol ; MPP+ ; 1-methyl-4-phenylpyridinium ; PD ; Parkinson&rsquo ; s disease ; GSK-3 ; Glycogen synthase kinase-3 ; GSK-3β ; Glycogen synthase kinase-3 beta ; AKT ; Protein kinase B ; MMP ; Mitochondrial membrane potential ; PI3K ; Phosphatidylinositol 3-kinase ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; MTT ; 3-(4 ; 5-dimethylthiazol-2yl)-2 ; 5-diphenyltetrazolium bromide

刊名：Neuroscience Letters

出版年：2017

2.MPP⁺ inhibits mGluR1/5-mediated long-term depression in mouse hippocampus by calpain activation

作者：Junyao Li^a ; ¹ ; Hui Chen^a ; ¹ ; Shengbing Wu^a ; Yuefa Cheng^b ; Qinglin Li^a ; Jing Wang^a ; ^{wangjing2161@126.com} ; Guoqi Zhu^a ; ^{guoqizhu@gmail.com}

关键词：MPP+ ; Calpain ; DHPG ; Hippocampus ; Long-term depression

刊名：European Journal of Pharmacology

出版年：2017

3.The significance of rotational behavior and sensitivity of striatal dopamine receptors in hemiparkinsonian rats: A comparative study of lactacystin and 6-OHDA

作者：Jolanta Konieczny^a ; ^{koniecz@if-pan.krakow.pl} ; Anna Czarnecka^a ; ^&dagger ; ; Tomasz Lenda^a ; Kinga Kamińska^a ; Lucyna Antkiewicz-Michaluk^b

关键词：DA ; dopamine ; DOPAC ; dihydroxyphenylacetic acid ; HVA ; homovanilic acid ; MPP+ ; 1-methyl-4-phenylpyridinium ion ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; PD ; Parkinson&rsquo ; s disease ; SN ; substantia nigra ; SNc ; substantia nigra pars compacta ; SNr ; substantia nigra pars reticulata ; UPS ; ubiquitin&ndash ; proteasome system

刊名：Neuroscience

出版年：2017

4.Effects of frequently used pharmaceutical excipients on the organic cation transporters 1-3 and peptide transporters 1/2 stably expressed in MDCKII cells

作者：Marcus Otter ; Stefan Oswald ; Werner Siegmund ; Markus Keiser ; ^{markus.keiser@uni-greifswald.de}

关键词：Pharmaceutical excipients ; Solubilizing agents ; Drug transporter ; Uptake transport ; Organic cation transporter (OCT) ; Peptide transporter (PEPT) ; Polyethylene glycol (PEG) ; Hydroxypropyl-β-cyclodextrin ; Solutol HS 15 (macrogol 15 hydroxystearate ; polyoxyl 15 hydroxystearate) ; Cremophor ; Tween (polysorbate) ; Kolliphor (poloxamer) ; MDCK cells ; In vitro ; Cell model ; Competition assay ; Inhibition assay

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

5.In-vivo evidence that high mobility group box 1 exerts deleterious effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model and Parkinson's disease which can be attenuated by glycyrrhizin

作者：Matteo Santoro^a ; ¹ ; Walter Maetzler^b ; ^c ; ¹ ; Petros Stathakos^a ; Heather L. Martin^a ; Markus A. Hobert^b ; ^c ; Tim W. Rattay^b ; ^c ; Thomas Gasser^b ; ^c ; John V. Forrester^a ; ^d ; ^e ; Daniela Berg^b ; ^c ; Kevin J. Tracey^f ; Gernot Riedel^a ; Peter Teismann^a ; ^{pteismann@gmx.de" class="auth_mail" title="E-mail the corresponding author}

关键词：COX ; cyclooxygenase ; CSF ; Cerebrospinal fluid ; DOPAC ; 3 ; 4-Dihydroxyphenylacetic acid ; GFAP ; glial fibrillary acidic protein ; H&Y ; Hoehn & Yahr ; HMGB1 ; high-mobility group box 1 ; HVA ; homovanillic acid ; MPP+ ; ; 1-methyl-4-phenylpyridinium ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; OD ; optical density ; PD ; Parkinson's disease ; RAGE ; receptor for advanced glycation endproducts ; SNpc ; substantia nigra pars compacta ; TH ; tyrosine-hydroxylase ; TNF-α ; tumour necrosis factor-alpha ; Wt ; wil

刊名：Neurobiology of Disease

出版年：2016

6.Alteration of nuclear factor-kappaB pathway promote neuroinflammation depending on the functions of estrogen receptors in substantia nigra after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment

作者：Soham Mitra^a ; ^{soham_envs@yahoo.co.in" class="auth_mail" title="E-mail the corresponding author} ; Nabanita Ghosh^a ; ^{ngdiya@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Priyobrata Sinha^b ; ^{priyobiochem@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Nilkanta Chakrabarti^b ; ^{nilchakra@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Arindam Bhattacharyya^a ; ^{arindam19@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; ^{arigene@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：PD ; Parkinson's disease ; SN ; substantia nigra ; Iba1 ; ionized calcium binding adaptor molecule 1 ; MPP+ ; 1-methyl-4-phenylpyridinium ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; TNF-α ; tumor necrosis factor-alpha ; b.w. ; body weight ; GFAP ; glial fibrillary acidic protein ; NF-κB ; nuclear factor kappa B

刊名：Neuroscience Letters

出版年：2016

7.Opening of ATP-sensitive K⁺ (K_ATP) channels enhance hydroxyl radical generation induced by MPP⁺ in rat striatum

作者：Toshio Obata^a ; ^{t-obata@osaka-aoyama.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Michiko Nakashima^b

关键词：DA ; dopamine ; OH ; hydroxyl radical ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; MPP+ ; ; 1-methyl-4-phenylpyridinium ion ; DHBA ; dihydroxybenzoic acid ; MAO ; monoamine oxidase

刊名：Journal of the Neurological Sciences

出版年：2016

8.Involvement of IGF-1 receptor signaling pathway in the neuroprotective effects of Icaritin against MPP⁺-induced toxicity in MES23.5 cells

作者：Ming-Chun Jiang^a ; ^b ; ^c ; ^d ; Xiao-Han Chen^a ; ^b ; Xia Zhao^a ; ^b ; Xue-Jie Zhang^a ; ^b ; Wen-Fang Chen^a ; ^b ; ^{chenwenfangqd@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Icaritin ; 1-Methyl-4-phenylpyridinium ion ; Insulin-like growth factor-1 receptor ; Akt ; ERK1/2 ; MES23.5 cells

刊名：European Journal of Pharmacology

出版年：2016

9.Protective effects of DJ-1 medicated Akt phosphorylation on mitochondrial function are promoted by Da-Bu-Yin-Wan in 1-methyl-4-phenylpyridinium-treated human neuroblastoma SH-SY5Y cells

作者：Yi Zhang^a ; ^f ; ¹ ; ^{zy_dalian@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; ^{yizhang@bucm.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Xiao-Gang Gong^a ; ^g ; ¹ ; Zhen-Zhen Wang^b ; Hong-Mei Sun^a ; ^{hm.sun@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Zhen-Yu Guo^a ; Cong Gai^a ; Jing-Hong Hu^c ; Ling Ma^a ; Ping Li^d ; Nai-Hong Chen^b ; ^e

关键词：Parkinson's disease ; Mitochondrial dysfunction ; DJ-1 ; Akt ; Phosphorylation ; Da-Bu-Yin-Wan

刊名：Journal of Ethnopharmacology

出版年：2016

10.Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson’s disease

作者：Brí ; gida R. Pinho^a ; Sara D. Reis^a ; Pedro Guedes-Dias^a ; Ana Leitã ; o-Rocha^a ; Clara Quintas^a ; Patrí ; cia Valentã ; o^b ; Paula B. Andrade^b ; Miguel M. Santos^c ; ^d ; Jorge M.A. Oliveira^a ; ^{jorgemao@ff.up.pt" class="auth_mail" title="E-mail the corresponding author}

关键词：Abdil solution ; antibody dilution solution ; A.U. ; arbitrary units ; BBB ; blood brain barrier ; BSA ; bovine serum albumin ; DCPIP ; 2 ; 6-dichlorophenolindophenol ; DD ; deacetylase domain ; dpf ; days post fertilization ; DMB ; dynein motor binding ; HAD ; HDAC association domain ; HDAC ; histone deacetylase ; MPP+ ; 1-methyl-4-phenylpyridinium ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; NES ; nuclear export signal ; NLS ; nuclear localization signal ; PBA ; 4-phenylbutyrate ; PBST ; PBS with 0.05% Tween 20 ; PB

刊名：Pharmacological Research

出版年：2016

按检索点细分(454)

题名(40)

关键词(133)

文摘(359)

按出版年细分(454)

2027年及以后(19)

2017年(4)

2016年(26)

2015年(6)

2013年(19)

2012年(23)

2011年(25)

2010年(23)

2009年(17)

2008年(21)

2007年(25)

2006年(26)

2005年(17)

2004年(11)

2003年(29)

2002年(21)

2001年(25)

2000年(17)

2000年及以前(100)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700