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在“Elsevier电子期刊”中，命中：5,443条，耗时：0.0949567 秒

在所有数据库中总计命中：9,369条

1.Polyfluorinated salicylic acid derivatives as analogs of known drugs: Synthesis, molecular docking and biological evaluation

作者：E.V. Shchegol'kov^a ; ^{schegolkov@ios.uran.ru} ; I.V. Shchur^a ; Ya.V. Burgart^a ; V.I. Saloutin^a ; A.N. Trefilova^b ; G.A. Ljushina^b ; S.Yu. Solodnikov^b ; L.N. Markova^b ; V.V. Maslova^b ; O.P. Krasnykh^b ; S.S. Borisevich^c ; S.L. Khursan^c

关键词：Polyfluoronated salicylates ; Nucleophilic substitution ; ortho-Methoxylation ; Molecular docking ; Anti-inflammatory and analgesic activities ; COX-1 inhibition ; Toxicity ; Permeability

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.Synthesis, anticholinesterase activity and molecular modeling study of novel carbamate-substituted thymol/carvacrol derivatives

作者：Belma Zengin Kurt^a ; Isil Gazioglu^b ; Aydan Dag^a ; Ramin Ekhteiari Salmas^c ; Gü ; lru Kayık^d ; Serdar Durdagi^c ; ^{serdar.durdagi@med.bau.edu.tr} ; Fatih Sonmez^e ; ^{fsonmez@sakarya.edu.tr}

关键词：Thymol ; Carvacrol ; Carbamate ; Alzheimer&rsquo ; s disease ; Molecular docking ; Molecular dynamics (MD) simulations ; MM-PBSA ; Induced fit docking (IFD)

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

3.Influences of size-fractionated humic acids on arsenite and arsenate complexation and toxicity to Daphnia magna

作者：Jinqian Ren^a ; Wenhong Fan^a ; ^{fanwh@buaa.edu.cn} ; Xiangrui Wang^a ; Qingquan Ma^a ; Xiaomin Li^a ; Zhizhen Xu^b ; Chaoyang Wei^c

关键词：Inorganic arsenic ; DOM property ; Molecular weight ; Complexation ; Toxicity

刊名：Water Research

出版年：2017

4.Molecular mechanisms of PFOA-induced toxicity in animals and humans: Implications for health risks

作者：Kan Li^a ; Peng Gao^b ; Ping Xiang^a ; Xuxiang Zhang^a ; Xinyi Cui^a ; ^{lizzycui@nju.edu.cn} ; Lena Q. Ma^a ; ^b ; ^lqma@ufl.edu

关键词：Peroxisome proliferating receptor alpha (PPARα) ; Constitutive androstane receptor (CAR) ; Pregnane-X receptor (PXR) ; Mitochondrial pathway ; Tumor necrosis factor-α/nuclear factor κB (TNF-α/NF-κB) ; Nuclear lipid hyperaccumulation

刊名：Environment International

出版年：2017

5.Design, synthesis, biological evaluation, and molecular modeling studies of chalcone-rivastigmine hybrids as cholinesterase inhibitors

作者：Ling Wang^a ; ^&dagger ; ; ^{lingwang@scut.edu.cn} ; Yu Wang^b ; ^&dagger ; ; Yiguang Tian^a ; ^&dagger ; ; Jinling Shang^a ; Xiaoou Sun^a ; Hongzhuan Chen^b ; Hao Wang^b ; ^{angela_wanghao@hotmail.com} ; Wen Tan^a ; ^{went@scut.edu.cn}

关键词：Cholinesterase inhibition ; Chalcone-rivastigmine hybrids ; Alzheimer&rsquo ; s disease ; Antioxidative ; Molecular docking

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

6.Removal characteristics of DON in pharmaceutical wastewater and its influence on the N-nitrosodimethylamine formation potential and acute toxicity of DOM

作者：Haidong Hu ; Cong Jiang ; Haijun Ma ; Lili Ding ; Jinju Geng ; Ke Xu ; Hui Huang ; Hongqiang Ren ; ^{hqren@nju.edu.cn}

关键词：Dissolved organic nitrogen (DON) ; Dissolved organic matter (DOM) ; Pharmaceutical wastewater ; Biotreatment ; N-nitrosodimethylamine (NDMA) ; Acute toxicity

刊名：Water Research

出版年：2017

7.Toxicity evaluation of the photoprotective compound LQFM048: Eye irritation, skin toxicity and genotoxic endpoints

作者：Renato Ivan de Á ; vila^a ; ¹ ; Marcelo de Sousa Vieira^a ; ¹ ; Marilisa Pedroso Nogueira Gaeti^b ; Larissa Cleres Moreira^a ; Laí ; s de Brito Rodrigues^a ; Gisele Augusto Rodrigues de Oliveira^a ; Aline Carvalho Batista^c ; Daniela Cristina Vinhal^d ; Ricardo Menegatti^d ; Marize Campos Valadares^a ; ^{marizeufg@gmail.com}

关键词：Alternative methods ; Eye irritation ; Genotoxicity ; Heterocyclic derivative ; Phototoxicity ; Skin sensitization

刊名：Toxicology

出版年：2017

8.mTOR Inhibition Mitigates Molecular and Biochemical Alterations of Vigabatrin-Induced Visual Field Toxicity in Mice

作者：Kara R. Vogel ; PhD^a ; Garrett R. Ainslie ; PhD^a ; Michelle A. Schmidt ; MS^b ; Jonathan P. Wisor ; PhD^b ; K. Michael Gibson ; PhD^a ; ^{mike.gibson@wsu.edu}

关键词：vigabatrin ; GABA ; mTOR ; gene expression ; visual evoked potentials ; visual field loss ; ARPE19 cells ; epilepsy

刊名：Pediatric Neurology

出版年：2017

9.Methotrexate-induced germ cell toxicity and the important role of zinc and SOD1: Investigation of molecular mechanisms

作者：Krishna Prahlad Maremanda ^{mkrishnaprahlad@gmail.com} ; G.B. Jena ; ^{gbjena@gmail.com} ; ^{gbjena@niper.ac.in}

关键词：Zinc ; SOD1 ; Methotrexate ; Rat testes ; Oxidative stress ; Diethyldithiocarbamate

刊名：Biochemical and Biophysical Research Communications

出版年：2017

10.Development of QSAR model to predict the ecotoxicity of Vibrio fischeri using COSMO-RS descriptors

作者：Ouahid Ben Ghanem^a ; ^{wahidghanem@gmail.com} ; M.I. Abdul Mutalib^a ; Jean-Marc Lé ; vê ; que^b ; Mohanad El-Harbawi^c

关键词：Ionic liquids ; Eco-toxicity ; Vibrio fischeri ; QSAR ; Sigma profile ; Molecular descriptors

刊名：Chemosphere

出版年：2017

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