搜索页_+Multi-kinase+inhibitors

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在“Elsevier电子期刊”中，命中：1,018条，耗时：0.096954 秒

在所有数据库中总计命中：1,658条

1.Quantitative structure activity relationship study of p38α MAP kinase inhibitors

作者：Eslam Pourbasheer^a ; Sajjad Ahmadpour^b ; Rohollah Zare-Dorabei^c ; Mehdi Nekoei^d ; ^{nekoei_m1@yahoo.com}

关键词：QSAR ; Genetic algorithm ; Stepwise ; Multiple linear regression ; Pyrazole derivative

刊名：Arabian Journal of Chemistry

出版年：2017

2.A graphene oxide-based multiplexed fluorescence assay for the detection of protein kinase activity in cell lysates and the evaluation of protein kinase inhibition

作者：Yong Huang ; ^{huangyong_2009@163.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae ; Huakui Huang ; Jian Qin ; Xiaoqian Liu ; Shulin Zhao ; ^{zhaoshulin001@163.com" class="auth_mail" title="E-mail the corresponding author}Author Vitae ; Zhen-Feng Chen ; Hong Liang ; ^{hliang@gxnu.edu.cn" class="auth_mail" title="E-mail the corresponding author}Author Vitae

关键词：Graphene oxide ; Multiplexed detection ; Protein kinase ; Cell lysates

刊名：Sensors & Actuators: B. Chemical

出版年：2017

3.The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

4.Tyrosine Kinase and Mammalian Target of Rapamycin Inhibitors in the Treatment of Advanced Renal Cell Carcinoma: Practical Clinical Implications of Pharmacologic Features

作者：Rahul A. Parikh¹ ; Leonard J. Appleman¹ ; ^{applemanlj@upmc.edu} ; Jan H. Beumer² ; Ewa Matczak³ ; Edward Chu¹

关键词：Decision-making ; Kidney cancer ; Management ; Pharmacology ; Targeted therapy

刊名：Clinical Genitourinary Cancer

出版年：2017

5.Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials

作者：Yaxiong Deng^a ; Zijun Wang^a ; Christopher Chang^b ; Liwei Lu^c ; Chak Sing Lau^d ; Qianjin Lu^a ; ^{qianlu5860@gmail.com}

关键词：IL ; interleukin ; TGF-β ; transforming growth factor β ; SLE ; systemic lupus erythematosus ; MS ; multiple sclerosis ; IBD ; inflammatory bowel diseases ; RA ; rheumatoid arthritis ; mAb ; monoclonal antibody ; IFN-γ ; interferon gamma ; TNF-α ; tumor necrosis factor alpha ; Tregs ; regulatory T cells ; EAE ; experimental autoimmune encephalitis ; ETS ; E26-transformation-specific ; STAT ; activators of transcription ; JAK ; Janus kinase ; NO ; nitric oxide ; LPS ; lipopolysaccharide ; ILC2 ; type II innate lymphoid cells ; RO

刊名：Human Immunology

出版年：2017

6.Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors

作者：Li Tan^a ; ^b ; ^j ; Deepak Gurbani^c ; ^j ; Ellen L. Weisberg^e ; ^f ; ^j ; Douglas S. Jones^g ; ^h ; ^j ; Suman Rao^a ; ^b ; ^g ; William D. Singer^c ; ^d ; Faviola M. Bernard^c ; ^d ; Samar Mowafy^a ; ^b ; ⁱ ; Annie Jenney^g ; Guangyan Du^a ; ^b ; Atsushi Nonami^e ; ^f ; James D. Griffin^e ; ^f ; Douglas A. Lauffenburger^h ; Kenneth D. Westover^c ; ^d ; ^{Kenneth.Westover@UTSouthwestern.edu} ; Peter K. Sorger^g ; ^{Peter_Sorger@hms.harvard.edu} ; Nathanael S. Gray^a ; ^b ; ^{Nathanael_Gray@dfci.harvard.edu}

关键词：TAK1 ; Polypharmacology ; Multitarget ; Cancer ; Cytokine secretion

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

7.Tyrosine kinase inhibitors potentiate anti-myeloma activity of proteasome inhibitor carfilzomib in resistant multiple myeloma cell lines and patient samples

作者：Lin Ao¹ ; Wooin Lee² ; Kyung-Bo Kim¹

刊名：Drug Metabolism and Pharmacokinetics

出版年：2017

8.Niclosamide ethanolamine inhibits artery constriction

作者：Shan-Liang Li^a ; Jie Yan^a ; Yan-Qiu Zhang^a ; Chang-Lin Zhen^a ; Ming-Yu Liu^a ; Jing Jin^a ; Jin-Lai Gao^a ; Xiao-Lin Xiao^a ; Xin Shen^a ; Yu Tai^a ; Nan Hu^a ; Xin-Zi Zhang^a ; Zhi-Jie Sun^b ; De-Li Dong^a ; ^{dongdeli@ems.hrbmu.edu.cn}

关键词：Acetylcholine chloride (PubChem CID ; 6060) ; Carbonyl cyanide m-chlorophenylhydrazone (PubChem CID ; 2603) ; Cyclopiazonic acid (PubChem CID ; 54682463) ; Glibenclamide (PubChem CID ; 3488) ; Paxilline (PubChem CID ; 105008) ; Phenylephrine hydrochloride (PubChem CID ; 5284443) ; Niclosamide ethanolamine (PubChem CID ; 14992)

刊名：Pharmacological Research

出版年：2017

9.PLK1, A Potential Target for Cancer Therapy

作者：Zhixian Liu^* ; Qingrong Sun^&dagger ; ; Xiaosheng Wang^* ; ^{xiaosheng.wang@cpu.edu.cn}

刊名：Translational Oncology

出版年：2017

10.Expanding the structural diversity of diarylureas as multi-target tyrosine kinase inhibitors

作者：Yuanyuan Shan^a ; ^&dagger ; ; Chen Wang^b ; ^&dagger ; ; Lin Zhang^b ; Jinfeng Wang^b ; Maoyi Wang^a ; Yalin Dong^a ; ^{dongyalin@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Diarylurea ; Multi-target ; Receptor tyrosine kinase ; Inhibitor ; Structural diversity

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

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