搜索页_ N-acetyl-l-cysteine (NAC)

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1.Sensing tyrosine enantiomers by using chiral CdSe/CdS quantum dots capped with N-acetyl-l-cysteine

作者：Fang Gao^a ; Shiyao Ma^a ; Xincai Xiao^a ; Yan Hu^a ; Dan Zhao^a ; ; Zhike He^b ;

关键词：Chiral recognition ; Tyrosine ; Quantum dots ; Circular dichroism ; N-acetyl-l-cysteine

刊名：Talanta

出版年：2017

2.Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418

作者：Isabelle V. Maucher^a ; Michael Rü ; hl^a ; Simon B.M. Kretschmer^a ; Bettina Hofmann^a ; Benjamin Kü ; hn^a ; Jasmin Fettel^a ; Anja Vogel^a ; ^b ; Karsten T. Flü ; gel^a ; Georg Manolikakes^c ; Nadine Hellmuth^a ; Ann-Kathrin Hä ; fner^a ; Vahid Golghalyani^a ; Ann-Katrin Ball^a ; Matthias Piesche^d ; ^g ; Carmela Matrone^d ; Gerd Geisslinger^b ; ^e ; Michael J. Parnham^b ; Michael Karas^a ; Dieter Steinhilber^a ; Jessica Roos^a ; ¹ ; ^{roos@pharmchem.uni-frankfurt.de} ; Thorsten J. Maier^d ; ^f ; ¹ ; ^{maier@biomed.au.dk}

关键词：AA ; arachidonic acid ; methyl-BQ ; 2 ; 5-dimethyl-1 ; 4-benzoquinone ; CDDO ; CDDO-methylester ; methoxy-BQ ; 2 ; 3-dimethoxy-5-methyl-p-benzoquinone ; methoxy-NS ; 3-methoxy-β-nitrostyrene ; DMF ; dimethyl fumarate ; GSH ; glutathione ; OH-BQ ; 2 ; 5-dihydroxy-1 ; 4-benzoquinone ; HPLC ; high-performance liquid chromatography ; H(P)ETE ; hydro (peroxy-) eicosatetraenoic acid ; LT ; leukotrienes ; MS ; mass spectrometry ; NAC ; N-acetylcysteine ; NAPQI ; N-acetyl-p-benzoquinone imine ; NEM ; N-ethylmaleimide ; NFA ; nitro-fatty acid

刊名：Biochemical Pharmacology

出版年：2017

3.Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway

作者：Xia Li¹ ; Xing-Xing Fan¹ ; Ze-Bo Jiang ; Wings TY Loo ; Xiao-Jun Yao ; Elaine Lai-Han Leung ; ^{lhleung@must.edu.mo} ; Louis WC Chow ; ^{wcchow@must.edu.mo} ; Liang Liu ; ^{lliu@must.edu.mo}

关键词：NSCLC ; non-small cell lung cancer cell ; ROS ; reactive oxygen species ; EGFR ; epidermal growth factor receptor ; T790M ; a substitution mutation of threonine with methionine at position 790 of EGFR ; TrxR ; thioredoxin reductases ; MTT ; 3-(4 ; 5-dimetrylthiazol)-2 ; 5-diphenyltetrazolium bromide ; DCFDA ; dichlorofluorescein diacetate ; PBS ; phosphate-buffered saline ; RIPA ; radioimmunoprecipitation assay ; PARP ; poly (ADP-ribosyl) polymerase ; NAC ; N-acetyl-l-cysteine ; MG132 ; proteasomal degradation pathway inh

刊名：Pharmacological Research

出版年：2017

4.Simultaneous determination of individual isothiocyanates in plant samples by HPLC-DAD-MS following SPE and derivatization with N-acetyl-l-cysteine

作者：Tadeusz Pilipczuk^a ; Barbara Kusznierewicz^a ; Tomasz Chmiel^a ; Witold Przychodzeń^b ; Agnieszka Bartoszek^a ; ^{agnieszka.bartoszek@pg.gda.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：Isothiocyanates ; N-acetyl-l-cysteine ; Dithiocarbamates ; HPLC-DAD-MS ; SPE ; Brassicaceae

刊名：Food Chemistry

出版年：2017

5.Hollow carbon spheres trigger inflammasome-dependent IL-1β secretion in macrophages

作者：Fernando T. Andó ; n^a ; ^b ; ^c ; ¹ ; Sourav P. Mukherjee^a ; ¹ ; Isabel Gessner^d ; Laura Wortmann^d ; Lisong Xiao^d ; Kjell Hultenby^e ; Anna A. Shvedova^f ; ^g ; Sanjay Mathur^d ; Bengt Fadeel^a ; ^{Bengt.Fadeel@ki.se}

关键词：ASC ; apoptosis-associated speck-like protein ; CBMs ; carbon-based nanomaterials ; HCS ; hollow carbon spheres ; HMDM ; human monocyte-derived macrophages ; LAL ; limulus amoebocyte lysate ; LPS ; lipopolysaccharide ; NAC ; N-acetyl-cysteine ; NLRP3 ; NLR (nucleotide-binding domain and leucine-rich repeat containing) family pyrin domain containing 3 (also known as NALP3 ; for NACHT ; LRR and PYD domain-containing protein 3)

刊名：Carbon

出版年：2017

6.Ammonia promotes endothelial cell survival via the heme oxygenase-1-mediated release of carbon monoxide

作者：Xiao-Ming Liu ; Kelly J. Peyton ; William Durante ; ^{durantew@health.missouri.edu}

关键词：HO-1 ; heme oxygenase-1 ; Nrf2 ; NF-E2-related factor-2 ; ROS ; reactive oxygen species ; CO ; carbon monoxide ; HUVECs ; human umbilical vein endothelial cells ; MAECs ; mouse aortic endothelial cells ; MASMCs ; mouse aortic smooth muscle cells ; NH4Cl ; ammonium chloride ; NH4OH ; ammonium hydroxide ; NAC ; N-acetyl-L-cysteine ; PMSF ; phenylmethylsulfonyl fluoride ; CM-H2DCFDA ; 5-(and-6)-chloromethyl-2 ; 7-dichlorodihydrofluorescein diacetate acetyl ester ; GSK3β ; glycogen synthase kinase-3β ; GSK3β-P ; phospho (ser-9)

刊名：Free Radical Biology and Medicine

出版年：2017

7.Ascorbic acid, but not dehydroascorbic acid increases intracellular vitamin C content to decrease Hypoxia Inducible Factor -1 alpha activity and reduce malignant potential in human melanoma

作者：Adam P. Fischer ^{fischer35@marshall.edu} ; Sarah L. Miles ; ^{kittlaus1@marshall.edu}

关键词：BRAF ; Murine sarcoma viral (v-raf) oncogene homolog B1 ; HIF-1α ; Hypoxia inducible factor-1 alpha ; PHD ; prolyl hydroxylase ; FIH ; Factor Inhibiting HIF ; AA ; Ascorbic acid ; A2P ; Ascorbate 2-phosphate ; DHA ; Dehydroascorbic acid ; EDHB ; Ethyl 3 ; 4-dihydroxbenozoate ; SVCT ; Sodium dependent vitamin C transporter ; GLUT ; Glucose transporter ; NAC ; N-acetyl cysteine ; ChCl ; Choline chloride

刊名：Biomedicine & Pharmacotherapy

出版年：2017

8.Metformin prevents glucotoxicity by alleviating oxidative and ER stress-induced CD36 expression in pancreatic beta cells

作者：Jun Sung Moon^a ; ¹ ; Udayakumar Karunakaran^b ; ¹ ; Suma Elumalai^b ; In-Kyu Lee^c ; Hyoung Woo Lee^a ; Yong-Woon Kim^d ; ² ; Kyu Chang Won^a ; ^b ; ² ; ^{kcwon@med.yu.ac.kr}

关键词：CD36 ; Cluster determinant 36 ; GSIS ; Glucose-stimulated insulin secretion ; NAC ; N-acetyl cysteine ; SSO ; Sulfo-N-succinimidyl oleate

刊名：Journal of Diabetes and its Complications

出版年：2017

9.Resveratrol induces mitochondrial respiration and apoptosis in SW620 colon cancer cells

作者：Mª ; del Mar Blanquer-Rosselló ; Reyniel Herná ; ndez-Ló ; pez ; Pilar Roca ; Jordi Oliver ; ^{jordi.oliver@uib.es} ; Adamo Valle

关键词：ΔΨm ; mitochondrial membrane potential ; 2-DG ; 2-deoxyglucose ; 5-FU ; 5-fluorouracil ; ANT A ; antimycin A ; COX ; cytochrome c oxidase ; ERα ; estrogen receptor alpha ; ERβ ; estrogen receptor beta ; ERRα ; estrogen-related receptor alpha ; ETO ; etomoxir ; FCCP ; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone ; LDH ; lactate dehydrogenase ; MDC ; monodansylcadaverine ; mtDNA ; mitochondrial DNA ; MTG ; MitoTracker Green® ; MTT ; thiazolyl blue tetrazolium bromide ; NAC ; N-acetyl cysteine ; NAO ; 10-nonyl acridine

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

10.Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation

作者：Guang-Fei Wang^a ; ¹ ; Qincai Dong^b ; ¹ ; Yuanyuan Bai^b ; Jing Yuan^c ; Quanbin Xu^b ; Cheng Cao^b ; ^{cao_c@sohu.com} ; Xuan Liu^b ; ^{liux931932@163.com}

关键词：CIN ; chromosomal instability ; CKIs ; CDK inhibitors ; DDC ; sodium diethyldithiocarbamate trihydrate ; GSK-3 ; glycogen synthase kinase 3 ; NAC ; N-acetyl-L-cysteine ; PCM ; pericentriolar material ; PCNT ; pericentrin ; ROS ; reactive oxygen species ; SAC ; spindle assembly checkpoint ; SOD ; superoxide dismutase ; TPX2 ; Target Protein for Xenopus kinesin-like protein 2

刊名：Free Radical Biology and Medicine

出版年：2017

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