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在“Elsevier电子期刊”中，命中：18,746条，耗时：0.1759485 秒

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1.Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

作者：Jeanne G. Quirit^a ; ^{jgquirit@berkeley.edu} ; Sergey N. Lavrenov^b ; ^{satory@mail.ru} ; Kevin Poindexter^a ; ^{kpoindexter25@gmail.com} ; Janice Xu^a ; ^{jamicexu@scripps.edu} ; Christine Kyauk^a ; ^{ckyauk@berkeley.edu} ; Kathleen A. Durkin^c ; ^{durkin@berkeley.edu} ; Ida Aronchik^a ; ^{idaaronchik@gmail.com} ; Thomas Tomasiak^d ; ^{tomasiak@msg.ucsf.edu} ; Yaroslav A. Solomatin^b ; ^{hercules44@yandex.ru} ; Maria N. Preobrazhenskaya^b ; ^{satory@mail.ru} ; Gary L. Firestone^a ; ^{glfire@berkeley.edu}

关键词：Indole-3-carbinol analogues ; Ligand-target protein interactions ; NEDD4-1 ubiquitin ligase ; In silico computational modeling ; Anti-cancer compounds ; Melanoma cells

刊名：Biochemical Pharmacology

出版年：2017

2.Structure-based design and synthesis of imidazo[1,2-a]pyridine derivatives as novel and potent Nek2 inhibitors with in vitro and in vivo antitumor activities

作者：Jian-Bei Xi^a ; ¹ ; Yan-Fen Fang^a ; ¹ ; Brendan Frett^b ; ¹ ; Meng-Li Zhu^a ; Tong Zhu^a ; Yan-Nan Kong^a ; Feng-Jie Guan^a ; Yun Zhao^a ; Xiong-Wen Zhang^a ; ^{xwzhang@sat.ecnu.edu.cn} ; Hong-yu Li^b ; ^HLi2@uams.ed ; Ming-Liang Ma^a ; ^{mlma@brain.ecnu.edu.cn} ; Wenhao Hu^a ; ^{whu@chem.ecnu.edu.cn}

关键词：Nek2 inhibitors ; Imidazo[1 ; 2-a]pyridine ; Antitumor activity ; Selectivity

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Fluorescent diphenylphosphonate-based probes for detection of serine protease activity during inflammation

作者：Laura E. Edgington-Mitchell^a ; ^{laura.edgington-mitchell@monash.edu} ; Nicholas Barlow^b ; Luigi Aurelio^b ; Aminath Samha^a ; Monika Szabo^b ; Bim Graham^b ; ^{bim.graham@monash.edu} ; Nigel Bunnett^a ; ^c ; ^{nigel.bunnett@monash.edu}

关键词：ABP ; activity-based probe ; DPP ; diphenylphosphonate ; NE ; neutrophil elastase ; PR-3 ; proteinase 3

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

4.Enhanced peroxidase-like activity of MoS₂/graphene oxide hybrid with light irradiation for glucose detection

作者：Jian Peng ; Jian Weng ; ^{jweng@xmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：MoS2 ; Graphene oxide ; Peroxidase-like ; Synergistic interaction ; Light ; Glucose detection

刊名：Biosensors and Bioelectronics

出版年：2017

5.Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice

作者：T.H. Pham^a ; ¹ ; I. Mendez-David^a ; ¹ ; C. Defaix^a ; B.P. Guiard^b ; L. Tritschler^a ; D.J. David^a ; A.M. Gardier^a ; ^{alain.gardier@u-psud.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Ketamine ; Serotonin ; Rapid antidepressant-like activity ; Medial prefrontal cortex ; Dorsal raphe nucleus ; Antidepressant drug ; Highly anxious BALB/cJ mice ; Microdialysis

刊名：Neuropharmacology

出版年：2017

6.PEG-functionalized zinc oxide nanoparticles induce apoptosis in breast cancer cells through reactive oxygen species-dependent impairment of DNA damage repair enzyme NEIL2

作者：Soumyananda Chakraborti^a ; ¹ ; ² ; Samik Chakraborty^b ; ¹ ; ³ ; Shilpi Saha^b ; Argha Manna^b ; Shruti Banerjee^b ; Arghya Adhikary^b ; ⁴ ; Shamila Sarwar^a ; Tapas K. Hazra^c ; Tanya Das^b ; ^{tanya@jcbose.ac.in} ; Pinak Chakrabarti^a ; ^{pinak@jcbose.ac.in}

关键词：Apoptosis ; Breast cancer ; NEIL2 ; p53 ; PEG-ZnO nanoparticles ; ROS ; Sp1

刊名：Free Radical Biology and Medicine

出版年：2017

7.Solgel-hydrothermal synthesis of Tb/Tourmaline/TiO₂ nano tubes and enhanced photocatalytic activity

作者：Fengping Huang ; Yuyu Guo ; ^{g66226074@163.com} ; Shuai Wang ; Shuang Zhang ; Mengli Cui

关键词：Nanocomposites ; Optical properties ; TiO2

刊名：Solid State Sciences

出版年：2017

8.Sulfanyl porphyrazines: Molecular barrel-like self-assembly in crystals, optical properties and in vitro photodynamic activity towards cancer cells

作者：Jaroslaw Piskorz^a ; ^{piskorzj@ump.edu.pl" class="auth_mail" title="E-mail the corresponding author} ; Sebastian Lijewski^b ; Mateusz Gierszewski^c ; Karolina Gorniak^b ; Lukasz Sobotta^a ; Barbara Wicher^b ; Ewa Tykarska^b ; Nejat Dü ; zgü ; neş^d ; Krystyna Konopka^d ; Marek Sikorski^c ; Maria Gdaniec^c ; Jadwiga Mielcarek^a ; Tomasz Goslinski^b

关键词：Porphyrazine ; Crystal structure ; Singlet oxygen ; Cytotoxicity ; Photodynamic therapy

刊名：Dyes and Pigments

出版年：2017

9.Structure and antioxidant superoxide dismutase activity of copper(II) hydrazone complexes

作者：Yogendra Pratap Singh^a ; Ram N. Patel^a ; ^{rnp64@ymail.com} ; Yogendra Singh^a ; Ray J. Butcher^b ; Pradeep Kumar Vishakarma^c ; R.K. Bhubon Singh^d

关键词：Mixed ligand complexes ; Antioxidant SOD mimics ; X-ray analysis ; Electron paramagnetic resonance(epr) spectra ; Cyclic voltammetry (CV)

刊名：Polyhedron

出版年：2017

10.Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition

作者：Balagani Sathish Kumar^a ; Kusumoori Ravi^a ; Amit Kumar Verma^a ; Kaneez Fatima^a ; Mohammad Hasanain^b ; Arjun Singh^a ; Jayanta Sarkar^b ; Suaib Luqman^a ; Debabrata Chanda^a ; Arvind S. Negi^a ; ^{arvindcimap@rediffmail.com}

关键词：Naphthoquinones ; Synthesis ; Regioselective ; Anticancer ; Topoisomerase ; Acute oral toxicity

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

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