搜索页_+NS5A+protein

常用资源

电子图书

期刊论文

学位会议

外文资源

特色专题

内部出版物

Wiley电子期刊(6)	SpringerLink电子期刊(79)	Elsevier电子期刊(224)
Springer电子图书(1)	NATURE电子期刊(9)	ACS电子期刊(26)

在“Elsevier电子期刊”中，命中：224条，耗时：0.0549785 秒

在所有数据库中总计命中：345条

1.New potent biaryl sulfate-based hepatitis C virus inhibitors

作者：Youngsu You^a ; ¹ ; Hee Sun Kim^b ; ¹ ; Il Hak Bae^a ; Seung Gi Lee^c ; Min Hyeok Jee^c ; Gyochang Keum^d ; Sung Key Jang^c ; ^{sungkey@postech.ac.kr} ; B. Moon Kim^a ; ^{kimbm@snu.ac.kr}

关键词：HCV ; NS5A inhibitor ; Biaryl sulfate ; Structure-activity relationship

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Golgi protein 73 facilitates the interaction of hepatitis C virus NS5A with apolipoprotein E to promote viral particle secretion

作者：Xuewu Zhang^a ; Tianci Wang^a ; Xuechen Dai^a ; Yecheng Zhang^a ; Hui Jiang^a ; Qi Zhang^a ; Fang Liu^a ; Kailang Wu^a ; Yingle Liu^a ; ^{mvlwu@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Hong Zhou^b ; ^{13476262815@139.com" class="auth_mail" title="E-mail the corresponding author} ; Jianguo Wu^a ; ^{jwu@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Hepatitis C virus ; HCV ; Golgi protein 73 ; GP73 ; Apolipoprotein E ; ApoE ; Hepatocellular carcinoma ; HCC ; Nonstructural protein 5A ; NS5A ; HCV particle assembly and secretion

刊名：Biochemical and Biophysical Research Communications

出版年：2016

3.Hepatitis C virus alters metabolism of biogenic polyamines by affecting expression of key enzymes of their metabolism

作者：Olga A. Smirnova^a ; Tuomo A. Keinanen^b ; Olga N. Ivanova^a ; Mervi T. Hyvonen^b ; Alex R. Khomutov^a ; Sergey N. Kochetkov^a ; Birke Bartosch^c ; ^d ; Alexander V. Ivanov^a ; ^{aivanov@yandex.ru}

关键词：Hepatitis C virus ; Polyamines ; Spermine ; Spermidine ; Metabolism

刊名：Biochemical and Biophysical Research Communications

出版年：2017

4.NS5A resistance leading to failure of 24-week therapy with sofosbuvir/ledipasvir and ribavirin for the treatment of hepatitis C genotype 1a infection in a HIV-1 co-infected patient

作者：Ksenia Sevastianova^a ; ^{ksenia.sevastianova@helsinki.fi" class="auth_mail" title="E-mail the corresponding author} ; Jonathan Dean^b ; Ciaran Bannan^a ; Miriam Coghlan^a ; Gillian Farrell^a ; Catherine Murray^a ; Cillian F. De Gascun^b ; Colm Bergin^a ; ^c

关键词：ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; cART ; combination antiretroviral therapy ; DAA ; direct-acting antiviral ; DDI ; drug&ndash ; drug interaction ; EOTR ; end-of-treatment response ; GT ; genotype ; HCV ; hepatitis C virus ; HIV-1 ; human immunodeficiency virus type 1 ; IFN ; interferon ; INR ; international normalized ratio ; LDV ; ledipasvir ; MELD ; Model for End-Stage Liver Disease ; NS3 ; non-structural protein 3 ; NS5A ; non-structural protein 5A ; NS5B ; non-structural protein 5B ; PI ; pr

刊名：Journal of Clinical Virology

出版年：2016

5.Duplication of the V3 domain in hepatitis C virus (1b) NS5A protein: Clonal analysis and physicochemical properties related to hepatocellular carcinoma occurrence

关键词：Hepatitis C virus ; NS5A-V3 domain ; Hepatocellular carcinoma ; Duplication ; Genetic variability

刊名：Journal of Clinical Virology

出版年：2016

6.NS5ATP6 modulates intracellular triglyceride content through FGF21 and independently of SIRT1 and SREBP1

作者：Zhongshu Li^a ; ^b ; Shenghu Feng^a ; ^c ; Li Zhou^a ; ^c ; Shunai Liu^a ; ^b ; ^{liusa1031@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Jun Cheng^a ; ^b ; ^{chengj0817@sina.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：NS5ATP6 ; FGF21 ; miR-577 ; SIRT1 ; SREBP1

刊名：Biochemical and Biophysical Research Communications

出版年：2016

7.Polymeric hepatitis C virus non-structural protein 5A nanocapsules induce intrahepatic antigen-specific immune responses

作者：Michael Fichter^a ; Keti Piradashvili^b ; Anette Pietrzak-Nguyen^a ; Leah Pretsch^a ; Gabor Kuhn^b ; ^d ; Susanne Strand^c ; Markus Knuf^a ; ^e ; Fred Zepp^a ; Frederik R. Wurm^b ; Volker Mailä ; nder^b ; ^d ; Katharina Landfester^b ; Stephan Gehring^a ; ^{stephan.gehring@uni-mainz.de" class="auth_mail" title="E-mail the corresponding author}

关键词：HCV NS5A ; Immunization ; Vaccination ; MPLA ; Nanocapsules

刊名：Biomaterials

出版年：2016

8.Structure-activity relationships of proline modifications around the tetracyclic-indole class of NS5A inhibitors

作者：Ling Tong^a ; ^{ling.tong@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Wensheng Yu^a ; Craig A. Coburn^a ; Lei Chen^a ; Oleg Selyutin^a ; Qingbei Zeng^a ; Michael P. Dwyer^a ; Anilkumar G. Nair^a ; Bandarpalle B. Shankar^a ; Seong Heon Kim^a ; De-Yi Yang^a ; Stuart B. Rosenblum^a ; Rebecca T. Ruck^a ; Ian W. Davies^a ; Bin Hu^b ; Bin Zhong^b ; Jinglai Hao^b ; Tao Ji^b ; Shuai Zan^b ; Rong Liu^a ; Sony Agrawal^a ; Donna Carr^a ; Stephanie Curry^a ; Patricia McMonagle^a ; Karin Bystol^a ; Frederick Lahser^a ; Paul Ingravallo^a ; Shiying Chen^a ; Ernest Asante-Appiah^a ; Joseph A. Kozlowski^a

关键词：HCV NS5A inhibitor ; Elbasvir ; MK-8742 ; Direct-acting antiviral agents ; HCV infection treatment ; Indole based tetracyclic core

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

9.Kushenin induces the apoptosis of HCV-infected cells by blocking the PI3K-Akt-mTOR pathway via inhibiting NS5A

作者：Yi Zhou^a ; Na Chen^a ; Xiaojing Liu^a ; Shumei Lin^a ; Wenjuan Luo^b ; ^{wenjuanluoxa@163.com" class="auth_mail" title="E-mail the corresponding author} ; Min Liu^a ; ^{minliusx@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Kushenin ; HCV replication ; Cell apoptosis ; NS5A ; PI3K-Akt-mTOR

刊名：Experimental Cell Research

出版年：2016

10.Alternative core development around the tetracyclic indole class of HCV NS5A inhibitors

作者：Ling Tong^a ; ; Wensheng Yu^a ; Craig A. Coburn^a ; Peter T. Meinke^a ; Anilkumar G. Nair^a ; Michael P. Dwyer^a ; Lei Chen^a ; Oleg Selyutin^a ; Stuart B. Rosenblum^a ; Yueheng Jiang^a ; James Fells^a ; Bin Hu^b ; Bin Zhong^b ; Richard M. Soll^b ; Rong Liu^a ; Sony Agrawal^a ; Ellen Xia^a ; Ying Zhai^a ; Rong Kong^a ; Paul Ingravallo^a ; Amin Nomeir^a ; Ernest Asante-Appiah^a ; Joseph A. Kozlowski^a

关键词：HCV NS5A inhibitor ; Elbasvir ; MK-8742 ; Direct-acting antiviral agents ; DAA ; HCV infection treatment ; Tetracyclic core

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

按检索点细分(224)

题名(73)

关键词(32)

文摘(177)

按出版年细分(224)

2027年及以后(11)

2017年(2)

2016年(11)

2015年(3)

2014年(1)

2013年(17)

2012年(19)

2011年(17)

2010年(18)

2009年(17)

2008年(8)

2007年(7)

2006年(10)

2005年(9)

2004年(6)

2003年(7)

2002年(12)

2001年(10)

2000年(6)

2000年及以前(33)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700