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在“Elsevier电子期刊”中，命中：1,513条，耗时：0.1109455 秒

在所有数据库中总计命中：2,342条

1.Body composition and metabolic outcomes after 96 weeks of treatment with ritonavir-boosted lopinavir plus either nucleoside or nucleotide reverse transcriptase inhibitors or raltegravir in patients with HIV with virological failure of a standard first-line antiretroviral therapy regimen: a substudy of the randomised, open-label, non-inferiority SEC

作者：Prof Mark A Boyd ; MD^a ; ^b ; ^{mark.boyd@adelaide.edu.au} ; Janaki Amin ; PhD^b ; Patrick W G Mallon ; PhD^c ; Nagalingeswaran Kumarasamy ; MD^d ; Johan Lombaard ; MD^e ; Prof Robin Wood ; PhD^f ; Prof Ploenchan Chetchotisakd ; MD^g ; Prof Praphan Phanuphak ; PhD^h ; Lerato Mohapi ; MDⁱ ; Iskandar Azwa ; MD^j ; Waldo H Belloso ; MD^k ; Prof Jean-Michel Molina ; PhD^l ; Prof Jennifer Hoy ; MD^m ; Cecilia L Moore ; MIPH^b ; Prof Sean Emery ; PhD^b ; Prof David A Cooper ; FAA^b ; on behalf of the SECOND-LINE Study Group^&dagger ;

刊名：The Lancet HIV

出版年：2017

2.Efavirenz dissolution enhancement III: Colloid milling, pharmacokinetics and electronic tongue evaluation

作者：Cristiane R.D. Hoffmeister^a ; Cinira Fandaruff^b ; Maí ; ra A. da Costa^a ; Lucio M. Cabral^c ; Luciana R. Pitta^d ; Stanley E.R. Bilatto^e ; ^f ; Livia D. Prado^a ; Daniel S. Corrê ; a^e ; ^f ; Leandro Tasso^g ; Marcos Antô ; nio S. Silva^b ; Helvé ; cio V.A. Rocha^a ; ^c ; ^{helveciorocha@far.fiocruz.br}

关键词：EFV ; efavirenz ; NNRTI ; non-nucleoside reverse transcriptase inhibitor ; HIV-1/AIDS ; human immunodeficiency virus type 1 infection ; SLS ; sodium lauryl sulfate ; HPC ; hydroxypropylcellulose ; HPMC ; hydroxypropylmetilcellulose ; NRTIs ; nucleoside reverse transcriptase inhibitors ; API ; active pharmaceutical ingredient ; CD ; cyclodextrin ; FDA ; Food and Drug Administration ; AUC ; area under the curve

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

3.Squarate-based carbocyclic nucleosides: Syntheses, computational analyses and anticancer/antiviral evaluation

作者：Meijun Lu^a ; ^b ; Qing-Bin Lu^b ; John F. Honek^a ; ^{jhonek@uwaterloo.ca}

关键词：Squaric acid ; Carbocyclic ; Nucleoside ; Anticancer ; Antiviral ; Bioisostere

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

4.Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design

作者：Fatiha Benmansour^a ; ^b ; ^c ; Iuni Trist^d ; Bruno Coutard^a ; ^b ; Etienne Decroly^a ; ^b ; Gilles Querat^e ; Andrea Brancale^d ; Karine Barral^a ; ^b ; ^c ; ^{karine.barral@inserm.fr}

关键词：Phenyl [(phenylcarbamoyl)amino]benzene-1-sulfonate derivatives ; N-Phenyl-[(phenylcarbamoyl)amino]benzene-1-sulfonamide derivatives ; Fragment-linking strategy ; Dengue virus ; NS5 methyltransferase inhibitors ; Antiviral activity

刊名：European Journal of Medicinal Chemistry

出版年：2017

5.Novel methods for the synthesis of 1,5,2-diazaphosphinines as potential inhibitors of HCV polymerase

作者：Daniel Da Costa^a ; ^{daniel.da.costa@merck.com} ; Arlè ; ne Roland^b ; Cyril B. Dousson^a

关键词：Hepatitis C virus ; 15 ; 2-Diazaphosphinines ; NS5B non-nucleoside inhibitors ; Thiadiazine bioisostere ; Allosteric inhibitors

刊名：Tetrahedron Letters

出版年：2017

6.Adenosine, but not guanosine, protects vaginal epithelial cells from Trichomonas vaginalis cytotoxicity

作者：Camila Braz Menezes^a ; ¹ ; Amanda Piccoli Frasson^a ; ^b ; ¹ ; Lucia Collares Meirelles^a ; Tiana Tasca^a ; ^{tiana.tasca@ufrgs.br}

关键词：Trichomonas vaginalis ; Cytopathogenesis ; NTPDase ; ecto-5&prime ; nucleotidase ; Adenosine ; Guanosine

刊名：Microbes and Infection

出版年：2017

7.Identifications of drug resistance mutations among antiretroviral treatment naive HIV-1 patients in Peninsular Malaysia

作者：Rozainanee Mohd Zain ; ^{rozainanee@yahoo.com} ; Nabila Ibrahim ; Suriani Ismail ; Jeyanthi Suppiah ; Nor Aziyah Mat Rahim ; Ravindran Thayan

关键词：HIV ; Resistance ; Malaysia ; Antiretroviral treatment naive

刊名：Asian Pacific Journal of Tropical Medicine

出版年：2017

8.Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy

作者：Ayako Hoshi^a ; Takeshi Sakamoto^a ; ^{sakamoto@josai.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Jun Takayama^a ; Meiyan Xuan^a ; Mari Okazaki^a ; Tracy L. Hartman^b ; Robert W. Buckheit Jr.^b ; Christophe Pannecouque^c ; Mark Cushman^d ; ^{cushman@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ADAM ; alkenyldiarylmethane ; NNRTI ; non-nucleoside reverse transcriptase inhibitor ; RT ; reverse transcriptase ; HIV-1 ; human immunodeficiency virus type 1 ; AIDS ; acquired immune deficiency syndrome ; ART ; antiretroviral therapy ; NRTI ; nucleoside reverse transcriptase inhibitor ; PI ; protease inhibitor ; INI ; integrase inhibitors ; FI ; fusion inhibitor ; CCR5I ; CC chemokine receptor inhibitor ; dNTPs ; deoxynucleoside triphosphate ; AZT ; azidothymidine (zidovudine) ; EDCI ; 1-(3-dimethylaminopropyl)-3-ethylc

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

9.Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase

作者：Claire Pierra Rouviè ; re^a ; ^{claire.pierra-rouviere@merck.com" class="auth_mail" title="E-mail the corresponding author} ; Agnè ; s Amador^b ; Eric Badaroux^b ; Thierry Convard^a ; Daniel Da Costa^a ; David Dukhan^a ; Ludovic Griffe^b ; Jean-Franç ; ois Griffon^a ; Massimiliano LaColla^c ; Fré ; dé ; ric Leroy^b ; Michel Liuzzi^d ; Anna Giulia Loi^d ; Joe McCarville^c ; Valeria Mascia^d ; Julien Milhau^a ; Loredana Onidi^d ; Jean-Laurent Paparin^a ; Rachid Rahali^a ; Efisio Sais^d ; Maria Seifer^c ; Dominique Surleraux^b ; David Standring^c ; Cyril Dousson^a

关键词：Hepatitis C virus ; Direct-acting antivirals ; NS5B non-nucleoside inhibitors ; Polymerase inhibitors ; Amide bioisostere ; Allosteric inhibitors

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

10.Structural optimization of non-nucleoside DNA methyltransferase inhibitor as anti-cancer agent

作者：Bo Zhong^a ; Sergei Vatolin^b ; Nethrie D. Idippily^a ; Rati Lama^a ; Laila A. Alhadad^a ; Frederic J. Reu^b ; ^{reuf@ccf.org" class="auth_mail" title="E-mail the corresponding author} ; Bin Su^a ; ^c ; ^{B.su@csuohio.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：DNMT1 ; Cancer ; Non-nucleosides ; Drug development

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

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