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在“Elsevier电子期刊”中，命中：277条，耗时：0.0839258 秒

在所有数据库中总计命中：402条

1.TRC4, an improved triptolide derivative, specifically targets to truncated form of retinoid X receptor-alpha in cancer cells

作者：Pei-yu Wang^a ; ¹ ; Wen-jun Zeng^a ; ¹ ; Jie Liu^a ; ¹ ; Yun-Long Wu^a ; Yinghui Ma^a ; Zhiping Zeng^a ; Ji-yan Pang^b ; ^{cespjy@mail.sysu.edu.cn} ; Xiao-kun Zhang^a ; Xiaomei Yan^c ; Alice Sze Tsai Wong^d ; Jin-Zhang Zeng^a ; ^{jzzeng@xmu.edu.cn}

关键词：Truncated retinoic X receptor-alpha ; AKT ; Cancer ; Triptolide ; Derivatives

刊名：Biochemical Pharmacology

出版年：2017

2.Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages

作者：Antonio J. Ruiz-Alcaraz^a ; ^ajruiz@um.es ; Marí ; a Tristá ; n-Manzano^a ; Antonio Guirado^b ; Jesú ; s Gá ; lvez^c ; Marí ; a Martí ; nez-Esparza^a ; Pilar Garcí ; a-Peñ ; arrubia^a ; ^{pigarcia@um.es}

关键词：ATF ; activating transcription factor ; CCM ; complete culture medium ; ERK ; extracellular signal-regulated kinase ; IKK ; IκB kinase ; IL-6 ; interleukin 6 ; JNK ; c-Jun N-terminal kinase ; LPS ; lipopolysaccharide ; MAPK ; mitogen-activated protein kinase ; NSAIDs ; non-steroidal anti-inflammatory drugs ; NFκB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; PAMP ; pathogen-associated molecular patterns ; PI3K ; phosphatidylinositol 3-kinase ; PKB ; protein kinase B ; PRRs ; PAMP recognition receptors

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

3.In vitro antioxidative and anti-inflammatory effects of the compound K-rich fraction BIOGF1K, prepared from Panax ginseng

作者：Muhammad Jahangir Hossen¹ ; ² ; ^☆ ; Yong Deog Hong³ ; ^☆ ; Kwang-Soo Baek¹ ; Sulgi Yoo¹ ; Yo Han Hong¹ ; Ji Hye Kim¹ ; Jeong-Oog Lee⁴ ; Donghyun Kim³ ; Junseong Park³ ; ^{superbody@amorepacific.com} ; Jae Youl Cho¹ ; ^{jaecho@skku.edu}

关键词：anti-inflammatory activity ; antioxidative activity ; BIOGF1K ; compound K ; Panax ginseng

刊名：Journal of Ginseng Research

出版年：2017

4.Overexpression of exogenous kidney-specific Ngal attenuates progressive cyst development and prolongs lifespan in a murine model of polycystic kidney disease

作者：Ellian Wang¹ ; ² ; Yuan-Yow Chiou³ ; Wen-Yih Jeng⁴ ; ⁵ ; Hsiu-Kuan Lin⁶ ; Hsi-Hui Lin⁶ ; Hsian-Jean Chin² ; Chi-Kuang Leo Wang² ; Shang-Shiuan Yu² ; ⁷ ; Shih-Chieh Tsai² ; Chih-Ying Chiang² ; Po-Hao Cheng² ; Hong-Jie Lin⁴ ; Si-Tse Jiang² ; ⁷ ; ^{stjiang@nlac.org.tw} ; Sou-Tyau Chiu⁸ ; ^{soutyauchiu@yahoo.com.tw} ; Hsiu Mei Hsieh-Li¹ ; ^{hmhsieh@ntnu.edu.tw}

关键词：cysts ; neutrophil gelatinase-associated lipocalin ; Pkd1

刊名：Kidney International

出版年：2017

5.A new steroidal saponin, furotrilliumoside from Trillium tschonoskii inhibits lipopolysaccharide-induced inflammation in Raw264.7 cells by targeting PI3K/Akt, MARK and Nrf2/HO-1 pathways

作者：Ting Yan^a ; ^b ; Xiangyong Yu^a ; Xianduo Sun^c ; Dali Meng^a ; ^{mengdl@163.com} ; Jing-ming Jia^a ; ^{jiajingming@163.com}

关键词：FT ; furotrilliumoside ; LPS ; lipopolysaccharide ; NO ; nitric oxide ; iNOS ; inducible nitric oxide synthase ; COX-2 ; cyclooxygenase-2 ; TNF-α ; tumor necrosis factor-α ; IL-6 ; interleukin-6 ; IL-1β ; interleukin-1β ; PI3K ; phosphoinositide-3-kinase ; MARK ; mitogen-activated protein kinases ; HO-1 ; heme oxygenase-1 ; Nrf2 ; nuclear factor E2-related factor 2 ; NF-κB ; nuclear factor-κB ; IκBα ; inhibitory factor kappa B alpha

刊名：Fitoterapia

出版年：2016

6.Methylglyoxal activates NF-κB nuclear translocation and induces COX-2 expression via a p38-dependent pathway in synovial cells

作者：Chuan-Chao Lin^a ; ^b ; Chi-Ming Chan^c ; ^d ; Yi-Pin Huang^e ; Shu-Hao Hsu^e ; Chuen-Lin Huang^e ; ^f ; Su-Ju Tsai^b ; ^{sujutsai@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Methylglyoxal (MGO) ; Nuclear factor-kappa B (NF-κB) ; Cyclooxygenase (COX)-2 ; Mitogen-activated protein kinase (MAPK) ; Akt ; Mammalian target of rapamycin (mTOR) ; p70S6K ; Synovial cells

刊名：Life Sciences

出版年：2016

7.PDK1 in NF-κB signaling is a target of Xanthium strumarium methanolic extract-mediated anti-inflammatory activities

作者：Muhammad Jahangir Hossen^a ; ^b ; ¹ ; Jae Youl Cho^a ; ¹ ; Daewon Kim^c ; ^{dr_dwkim@dankook.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：Xs-ME ; methanolic extract of Xanthium strumarium ; HPLC ; high performance liquid chromatography ; PGE2 ; prostaglandin E2 ; NO ; nitric oxide ; COX ; cyclooxygenase ; iNOS ; inducible NO synthase ; TLR ; Toll-like receptor (TLR) ; NF-κB ; nuclear factor-κB ; Akt ; protein kinase B ; IKK ; IκBα kinase ; MyD88 ; myeloid differentiation primary response protein-88 ; PDK1 ; 3-phosphoinositide-dependent kinase 1 ; EIA ; enzyme immunoassay ; MTT ; (3&ndash4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; LPS ; lipopo

刊名：Journal of Ethnopharmacology

出版年：2016

8.Relaxin-2 improves diastolic function of pressure-overloaded rats via phospholamban by activating Akt

作者：Xin-xin Shuai¹ ; Yi-di Meng¹ ; Yong-xin Lu ; ^{yongxin_lu6@aliyun.com" class="auth_mail" title="E-mail the corresponding author} ; Guan-Hua Su ; Xiao-fang Tao ; Jun Han ; Su-Dan Xu ; Ping Luo

关键词：Relaxin ; Diastolic function ; Phospholamban ; Nuclear-target Akt

刊名：International Journal of Cardiology

出版年：2016

9.Oxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

作者：Sergio Portal-Nú ; ñ ; ez^a ; Pedro Esbrit^a ; Marí ; a José ; Alcaraz^b ; Raquel Largo^c ; ^{rlargo@fjd.es" class="auth_mail" title="E-mail the corresponding author} ; ^{rlargocarazo@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ADAMTS ; a disintegrin and metalloproteinase with thrombospondin motifs ; AGEs ; advanced glycation end products ; ATG ; autophagy-related gene ; Col2 ; type II collagen ; DNMT ; DNA methyltransferase ; ERK ; extracellular signal-regulated kinase ; HDAC ; histone deacetylase ; IGF-I ; insulin growth factor I ; iNOS ; inducible NO synthase ; IL ; interleukin ; MAPK ; mitogen-activated kinase ; miRNA ; micro RNA ; MMP ; metalloproteinase ; mTORC1 ; mammalian target of rapamycin complex 1 ; NF-κB ; nuclear factor κ B ; NO ; nitr

刊名：Biochemical Pharmacology

出版年：2016

10.Nanomedicine based curcumin and doxorubicin combination treatment of glioblastoma with scFv-targeted micelles: In vitro evaluation on 2D and 3D tumor models

作者：Can Sarisozen^a ; Shekhar Dhokai^a ; Edcar G. Tsikudo^a ; Ed Luther^b ; Ilya M. Rachman^c ; Vladimir P. Torchilin^a ; ^d ; ^{v.torchilin@neu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：NF-κB ; PI3K/Akt ; Curcumin ; GLUT-1 ; scFv ; Drug resistance ; Micelles ; Co-delivery ; Cancer cell spheroids

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2016

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