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在“Elsevier电子期刊”中，命中：1,134条，耗时：0.0249848 秒

在所有数据库中总计命中：1,755条

1.Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway

作者：Xia Li¹ ; Xing-Xing Fan¹ ; Ze-Bo Jiang ; Wings TY Loo ; Xiao-Jun Yao ; Elaine Lai-Han Leung ; ^{lhleung@must.edu.mo} ; Louis WC Chow ; ^{wcchow@must.edu.mo} ; Liang Liu ; ^{lliu@must.edu.mo}

关键词：NSCLC ; non-small cell lung cancer cell ; ROS ; reactive oxygen species ; EGFR ; epidermal growth factor receptor ; T790M ; a substitution mutation of threonine with methionine at position 790 of EGFR ; TrxR ; thioredoxin reductases ; MTT ; 3-(4 ; 5-dimetrylthiazol)-2 ; 5-diphenyltetrazolium bromide ; DCFDA ; dichlorofluorescein diacetate ; PBS ; phosphate-buffered saline ; RIPA ; radioimmunoprecipitation assay ; PARP ; poly (ADP-ribosyl) polymerase ; NAC ; N-acetyl-l-cysteine ; MG132 ; proteasomal degradation pathway inh

刊名：Pharmacological Research

出版年：2017

2.MiR-335 regulates the chemo-radioresistance of small cell lung cancer cells by targeting PARP-1

作者：Yingshan Luo^a ; Lihua Tong^a ; Hui Meng^a ; Weiliang Zhu^a ; Linlang Guo^b ; Ting Wei^a ; ^{258077534@qq.com} ; Jian Zhang^a ; ^{blacktiger@139.com}

关键词：SCLC ; small cell lung cancer ; PARP-1 ; Poly [ADP-ribose] polymerase 1 ; miRNAs ; microRNAs ; ccRcc ; clear cell renal cell carcinoma ; NAD + ; ; nicotinamide adenine dinucleotide ; qRT-PCR ; quantitative real-time PCR ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; DDP ; cisplatin ; VP-16 ; etoposide ; ADM ; Adriamycin ; CCK-8 ; Cell Counting Kit-8 ; IC50 ; the half maximal inhibitory concentration of a substance

刊名：Gene

出版年：2017

3.Lipopolysaccharides-stimulated macrophage products enhance Withaferin A-induced apoptosis via activation of caspases and inhibition of NF-κB pathway in human cancer cells

作者：Liang Piao^a ; ¹ ; Zhao Canguo^a ; ¹ ; Lu Wenjie^a ; Cheng Xiaoli^b ; Shi Wenli^c ; Lu Li^a ; ^d ; ^{2000990017@gzhmu.edu.cn} ; ^{925295339@qq.com}

关键词：Macrophage ; Withaferin A ; Apoptosis ; NF-κB pathway

刊名：Molecular Immunology

出版年：2017

4.DNA Repair in Prostate Cancer: Biology and Clinical Implications

作者：Joaquin Mateo^a ; ^b ; Gunther Boysen^a ; Christopher E. Barbieri^c ; ^d ; ^e ; Helen E. Bryant^f ; Elena Castro^g ; Pete S. Nelson^h ; ⁱ ; David Olmos^g ; ^j ; Colin C. Pritchard^h ; Mark A. Rubin^d ; ^e ; ^k ; Johann S. de Bono^a ; ^b ; ^{johann.de-bono@icr.ac.uk}

关键词：Prostate cancer ; DNA repair ; PARP ; BRCA ; Personalized medicine ; DNA damage

刊名：European Urology

出版年：2017

5.Peanut sprout extract attenuates cisplatin-induced ototoxicity by induction of the Akt/Nrf2-mediated redox pathway

作者：Cha Kyung Youn^a ; ^b ; Eu-Ri Jo^a ; Ju-Hwan Sim^a ; Sung Il Cho^a ; ^{chosi@chosun.ac.kr}

关键词：Cisplatin ; Ototoxicity ; Cell death ; Peanut sprout ; Apoptosis

刊名：International Journal of Pediatric Otorhinolaryngology

出版年：2017

6.Methotrexate prevents epidural fibrosis through endoplasmic reticulum stress signalling pathway

作者：Hui Chen¹ ; Lianqi Yan¹ ; Jingcheng Wang ; ^{jingchengwyz@163.com} ; Yu Sun ; ^{docyusun@126.com} ; Xiaolei Li ; Shuai Zhao ; Daxin Wang ; Gengyao Zhu ; Yuan Liang

关键词：Methotrexate ; Endoplasmic reticulum stress ; Fibroblast apoptosis ; Epidural fibrosis

刊名：European Journal of Pharmacology

出版年：2017

7.Oldenlandia diffusa suppresses metastatic potential through inhibiting matrix metalloproteinase-9 and intercellular adhesion molecule-1 expression via p38 and ERK1/2 MAPK pathways and induces apoptosis in human breast cancer MCF-7 cells

作者：Tae-Wook Chung^a ; ¹ ; ^{chungtw@hanmail.net} ; Hyunju Choi^b ; ¹ ; ^{chj204@skku.edu} ; Ji-Min Lee^b ; ^jml@skku.edu ; Sun-Hyung Ha^b ; ^{sunghyungha@skku.edu} ; Choong-Hwan Kwak^b ; ^{kwak@skku.edu} ; Fukushi Abekura^b ; ^{pokusa6@hotmail.com} ; Jun-Young Park^b ; ^{wnsdud2057@naver.com} ; Young-Chae Chang^c ; ^{ycchang@cu.ac.kr} ; Ki-Tae Ha^a ; ^{haggis@pnu.ac.kr} ; Seung-Hak Cho^d ; ^{skcho38@hotmail.com} ; Hyeun Wook Chang^e ; ^{hwchang@yu.ac.kr} ; Young-Choon Lee^f ; ^{yclee@dau.ac.kr} ; Cheorl-Ho Kim^a ; ^{chkimbio@skku.edu}

关键词：OD ; Oldenlandia diffusa ; MMP ; matrix metalloproteinase ; ICAM-1 ; intercellular adhesion molecule-1 ; MOD ; methanol extracts of OD ; BOD ; buthanol extracts of OD ; PMA ; phorbol myristate acetate ; ECM ; extracellular matrix ; PARP ; ADP-ribose polymerase ; FBS ; fatal bovine serum ; TBS-T ; Tris-Buffered Saline Tween-20 ; HRP ; horseradish peroxidase

刊名：Journal of Ethnopharmacology

出版年：2017

8.Molecular mechanism of Antrodia cinnamomea sulfated polysaccharide on the suppression of lung cancer cell growth and migration via induction of transforming growth factor β receptor degradation

作者：Mei-Kuang Lu^a ; ^b ; ¹ ; ^{mklu@nricm.edu.tw} ; Tung-Yi Lin^c ; ^d ; ¹ ; Chi-Hsein Chao^a ; Chun-Hao Hu^d ; Hsien-Yeh Hsu^c ; ^d ; ^e ; ^{hsienyeh@gmail.com}

关键词：TGFRs ; transforming growth factor β receptors ; SPS ; sulfated polysaccharide ; NSPS ; non-sulfated polysaccharide ; FAK ; focal adhesion kinase ; Smurf2 ; Smad ubiquitination regulatory factor 2 ; UPP ; ubiquitin-proteasome pathway

刊名：International Journal of Biological Macromolecules

出版年：2017

9.Orobol derivatives and extracts from Cudrania tricuspidata fruits protect against 6-hydroxydomamine-induced neuronal cell death by enhancing proteasome activity and the ubiquitin/proteasome-dependent degradation of α-synuclein and synphilin-1

作者：Dong-Woo Kim^a ; Jaeyoung Kwon^b ; Su Jin Sim^c ; Dongho Lee^d ; ^{dongholee@korea.ac.kr} ; Woongchon Mar^a ; ^{mars@snu.ac.kr}

关键词：6-OHDA ; 6-hydroxydomamine ; PD ; Parkinson&rsquo ; s disease ; PARP ; poly (ADP-ribose) polymerase ; ROS ; reactive oxygen species ; UPP ; ubiquitin-proteasome pathway ; UPS ; ubiquitin-proteasome system ; CTE50 ; 50% ethanol extract from Cudrania tricuspidata fruits ; OB ; orobol ; POB ; 6-prenylorobol ; DPOB ; 6 ; 8-diprenylorobol

刊名：Journal of Functional Foods

出版年：2017

10.Polycyclic xanthones via pH-switched biotransformation of α-mangostin catalysed by horseradish peroxidase exhibited cytotoxicity against hepatoblastoma cells in vitro

作者：Jia-Jia Wu ^{wujiajia1045529@163.com} ; Ting Ma ^{maxueting0842910@163.com} ; Zhi-Min Wang ^{418973903@qq.com} ; Wen-Jun Xu ^{cpu_xuwenjun@163.com} ; Xue-Lian Yang ^{792697415@qq.com} ; Jian-Guang Luo ^{luojg@cpu.edu.cn} ; Ling-Yi Kong ; ^{cpu_lykong@126.com} ; Xiao-Bing Wang ; ^{xbwang@cpu.edu.cn}

关键词：HRP ; horseradish peroxidase ; MMP ; mitochondrial membrane potential ; PARP ; poly-(ADP-ribose)-polymerase ; ROS ; reactive oxygen species ; MAPK ; mitogen-activated protein kinase ; ERK ; extracellular signal-regulated kinase ; JNK ; c-Jun N-terminal kinases ; p38 ; p38 mitogen-activated protein kinase ; Bax ; Bcl-2 Associated X Protein ; Bcl-2 ; B cell lymphoma/lewkmia-2

刊名：Journal of Functional Foods

出版年：2017

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