搜索页_ PTEN/Akt pathway

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在“Elsevier电子期刊”中，命中：959条，耗时：0.0229899 秒

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1.MiR-222 promotes drug-resistance of breast cancer cells to adriamycin via modulation of PTEN/Akt/FOXO1 pathway

作者：Hongyu Shen^a ; ^b ; Dandan Wang^b ; Liangpeng Li^c ; Sujin Yang^a ; ^b ; Xiu Chen^a ; ^b ; Siying Zhou^b ; ^d ; Shanliang Zhong^e ; Jianhua Zhao^e ; ^{lcjyjhzhao@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jinhai Tang^a ; ^b ; ^{njmujhtang@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ADR ; adriamycin ; miRNA ; microRNA ; UTR ; untranslated region ; PTEN ; phosphatase a tensin homolog deleted on chromosome 10 ; PIP3 ; phosphatidylinositol-34 ; 5-triphosphate ; PIP2 ; diphosphate product ; IC50 ; the inhibitory concentration to produce 50% cell death ; FBS ; fetal bovine serum ; NC ; negative control ; PBS ; phosphate-buffered saline ; RT-qPCR ; real-time quantitative polymerase chain reaction assay ; MTT ; 3-[4 ; 5-dimethylthiazol-2-yl]-2 ; 5-diphenyltetrazolium-bromide ; DMSO ; dimethylsulfoxide ; KEGG ; K

刊名：Gene

出版年：2017

2.Repression of miR-217 protects against high glucose-induced podocyte injury and insulin resistance by restoring PTEN-mediated autophagy pathway

作者：Juan Sun^a ; Zhao Pin Li^b ; Rui Qin Zhang^a ; Hui Min Zhang^a ; ^{huiminzhanghn@163.com}

关键词：Diabetic nephropathy ; miR-217 ; Podocyte injury ; Insulin resistance ; Autophagy ; PTEN

刊名：Biochemical and Biophysical Research Communications

出版年：2017

3.Kinetic modelling of in vitro data of PI3K, mTOR1, PTEN enzymes and on-target inhibitors Rapamycin, BEZ235, and LY294002

作者：Alexey Goltsov^a ; ^{a.goltsov@abertay.ac.uk} ; Ghassan Tashkandi^b ; ^{s1163633@exseed.ed.ac.uk} ; Simon P. Langdon^b ; ^{Simon.Langdon@ed.ac.uk} ; David J. Harrison^c ; ^{David.Harrison@st-andrews.ac.uk} ; James L. Bown^a ; ^d ; ^{j.bown@abertay.ac.uk}

关键词：Kinetic modelling ; PI3K ; mTOR1 ; PTEN ; Rapamycin ; BEZ235

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

4.Activating AKT to inhibit JNK by troxerutin antagonizes radiation-induced PTEN activation

作者：Ping Xu^a ; ^{13273730271@163.com} ; Wen-Bo Zhang^b ; Xin-Hua Cai^a ; Pei-Yong Qiu^a ; Ming-Hua Hao^a ; Dan-Dan Lu^c

关键词：Troxerutin ; Thymus cell ; AKT ; PTEN ; JNK

刊名：European Journal of Pharmacology

出版年：2017

5.Umbelliferone reverses depression-like behavior in chronic unpredictable mild stress-induced rats by attenuating neuronal apoptosis via regulating ROCK/Akt pathway

作者：Tingting Qin ; Fang Fang ; Meiting Song ; Ruipeng Li ; Zhanqiang Ma ; ^{mazhanqiang0427@163.com" class="auth_mail" title="E-mail the corresponding author} ; Shiping Ma ; ^{spma@cpu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：ROCK ; Rho-associated protein kinase ; Akt ; protein kinase B ; PTEN ; phosphatase and tensin homolog ; GSK3β ; glycogen synthase kinase 3β ; CUMS ; chronic unpredictable mild stress ; CMC-Na ; carboxymethyl cellulose ; IL-1β ; interleukin 1β ; IL-6 ; interleukin 6 ; TNF-α ; tumour necrosis factor α ; ELISA ; enzyme-linked immunosorbent assay ; Umb ; umbelliferone ; Fas ; fasduil ; SPT ; sucrose preference test ; OFT ; open field test ; FST ; forced swimming test

刊名：Behavioural Brain Research

出版年：2017

6.Reaching the brain: Advances in optic nerve regeneration

作者：Larry I. Benowitz^a ; ^b ; ^{larry.benowitz@childrens.harvard.edu} ; Zhigang He^c ; ^d ; Jeffrey L. Goldberg^e

关键词：Axon regeneration ; Optic nerve ; Retinal ganglion cell ; klf-4 ; Oncomodulin ; Inflammation ; pten ; socs3 ; c-Myc ; Optic chiasm ; Lateral geniculate nucleus ; Eye transplantation

刊名：Experimental Neurology

出版年：2017

7.Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway

作者：Neera Nathan ; MD^a ; Kim M. Keppler-Noreuil ; MD^b ; Leslie G. Biesecker ; MD^b ; Joel Moss ; MD ; PhD^c ; Thomas N. Darling ; MD ; PhD^a ; ^{thomas.darling@usuhs.edu}

刊名：Dermatologic Clinics

出版年：2017

8.Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond

作者：Mary Nakazawa ; Natasha Kyprianou ; ^{nkypr2@uky.edu}

关键词：ADT ; Androgen deprivation therapy ; AR ; Androgen receptor ; CRPC ; Castration resistant prostate cancer ; DHT ; Dihydrotestosterone ; EGF ; Epidermal growth factor ; EMT ; Epithelial mesenchymal transition ; ERβ ; Estrogen receptor β ; FGF ; Fibroblast growth factor ; IGF ; Insulin-like growth factor ; MET ; Mesenchymal epithelial transition ; PDGF ; Platelet derived growth factor ; PI3 K ; Phosphatidylinositol 3-OH kinase ; PTEN ; Phosphatase tensin homolog ; RTK ; Receptor tyrosine kinase ; SHH ; Sonic Hedgehog ; TGFβ ; T

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

9.miR-221/222 enhance the tumorigenicity of human breast cancer stem cells via modulation of PTEN/Akt pathway

作者：Bailong Li^a ; Ying Lu^b ; Honghai Wang^c ; Xiaocui Han^b ; Jun Mao^b ; Jiazhi Li^b ; Lihui Yu^b ; Bo Wang^b ; Shujun Fan^b ; Xiaotang Yu^b ; Bo Song^b ; ^{yr0806@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：microRNA-221/222 ; PTEN/Akt pathway ; Cancer stem cell ; Breast cancer

刊名：Biomedicine & Pharmacotherapy

出版年：2016

10.Genomic profile in gestational and non-gestational choriocarcinomas

作者：Julia Bette Homem de Mello^a ; Priscila Daniele Ramos Cirilo^b ; Odair Carlito Michelin^c ; Maria Aparecida Custó ; dio Domingues^d ; Marilza Vieira Cunha Rudge^e ; Silvia Regina Rogatto^f ; ^g ; ¹ ; ^{silvia.regina.rogatto@rsyd.dk} ; ^{rogatto@fmb.unesp.br} ; Izildinha Maestá ; ^e ; ¹

关键词：Gestational choriocarcinoma ; Non-gestational choriocarcinoma ; Microsatellites ; Array comparative genomic hybridization ; Copy number alteration

刊名：Placenta

出版年：2017

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