搜索页_+Partial+agonism

常用资源

电子图书

期刊论文

学位会议

外文资源

特色专题

内部出版物

Wiley电子期刊(3)	NATURE电子期刊(3)	ACS电子期刊(38)
SpringerLink电子期刊(62)	Elsevier电子期刊(255)

在“Elsevier电子期刊”中，命中：255条，耗时：0.0210232 秒

在所有数据库中总计命中：361条

1.From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor

作者：Cristiano Bolchi^a ; Francesco Bavo^a ; Cecilia Gotti^b ; Laura Fumagalli^a ; Francesca Fasoli^b ; Matteo Binda^a ; Vanessa Mucchietto^b ; Miriam Sciaccaluga^c ; Simona Plutino^d ; Sergio Fucile^c ; ^d ; Marco Pallavicini^a ; ^{marco.pallavicini@unimi.it}

关键词：α4β2 nAChR ; α3β4 nAChR ; Benzodioxane ; Pyridodioxane ; Partial agonism ; Antagonism

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Vilazodone does not inhibit sexual behavior in male rats in contrast to paroxetine: A role for 5-HT_1A receptors?

作者：Ronald S. Oosting^a ; ^{R.S.Oosting@uu.nl" class="auth_mail" title="E-mail the corresponding author} ; Johnny S.W. Chan^a ; Berend Olivier^a ; ^b ; ^c ; Pradeep Banerjee^d

关键词：Preclinical ; Antidepressant ; Serotonin receptor ; Partial agonism

刊名：Neuropharmacology

出版年：2016

3.In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations

作者：Federica Ferrari^a ; Maria Camilla Cerlesi^a ; Davide Malfacini^a ; Laila Asth^b ; Elaine C. Gavioli^b ; Blair V. Journigan^c ; Uma Gayathri Kamakolanu^c ; Michael E. Meyer^c ; Dennis Yasuda^c ; Willma E. Polgar^d ; Anna Rizzi^a ; Remo Guerrini^e ; Chiara Ruzza^a ; Nurulain T. Zaveri^c ; Girolamo Calo^a ; ^{g.calo@unife.it}

关键词：NOP and classical opioid receptors ; Bioluminescence resonance energy transfer ; Calcium mobilization and mouse colon vas deferens and assays ; Receptor and [35S]GTPγS binding

刊名：European Journal of Pharmacology

出版年：2016

4.The antiproliferative and proapoptotic effects of cladosporols A and B are related to their different binding mode as PPARγ ligands

作者：Diana Zurlo^a ; ¹ ; Pamela Ziccardi^a ; ¹ ; Carolina Votino^a ; Tommaso Colangelo^a ; Carmen Cerchia^b ; Fabrizio Dal Piaz^c ; Sabrina Dallavalle^d ; Salvatore Moricca^e ; Ettore Novellino^b ; Antonio Lavecchia^b ; ^{antonio.lavecchia@unina.it" class="auth_mail" title="E-mail the corresponding author} ; Vittorio Colantuoni^a ; Angelo Lupo^a ; ^{lupo@unisannio.it" class="auth_mail" title="E-mail the corresponding author}

关键词：CAD ; caspase-activated deoxyribonuclease ; CRC ; colorectal cancer ; HR-ESI-MS ; high resolution electrospray ionization mass ; LBD ; ligand-binding domain ; MDA ; malondialdehyde ; NCoEx ; nuclear corepressor exchange factor ; PPARs ; peroxisome proliferator-activated receptors ; PBS ; phosphate saline buffer ; PPARγ ; peroxisome proliferator-activated receptor γ ; PPRE ; PPAR response element ; POX/PRODH ; proline oxidase/proline dehydrogenase ; RGZ ; rosiglitazone ; RSV ; Rous Sarcoma Virus ; RXR ; retinoid X receptor

刊名：Biochemical Pharmacology

出版年：2016

5.Terlipressin, a vasoactive prodrug recommended in hepatorenal syndrome, is an agonist of human V1, V2 and V1B receptors: Implications for its safety profile

关键词：Terlipressin ; PubChem CID ; 72081 ; [Arginine8]Vasopressin ; PubChem CID ; 90488786 ; [Lysine8]Vasopressin ; PubChem CID ; 90488785 ; SR49059 ; PubChem CID ; 60943

刊名：Pharmacological Research

出版年：2016

6.In vitro, molecular modeling and behavioral studies of 3-{[4-(5-methoxy-1H-indol-3-yl)-1,2,3,6-tetrahydropyridin-1-yl]methyl}-1,2-dihydroquinolin-2-one (D2AAK1) as a potential antipsychotic

作者：Agnieszka A. Kaczor^a ; ^b ; ^{agnieszka.kaczor@umlub.pl" class="auth_mail" title="E-mail the corresponding author} ; Katarzyna M. Targowska-Duda^c ; Barbara Budzyńska^d ; Grażyna Biała^d ; Andrea G. Silva^e ; Mariá ; n Castro^e

关键词：Antipsychotics ; Behavioral studies ; Homology modeling ; Molecular docking ; Molecular dynamics ; Schizophrenia

刊名：Neurochemistry International

出版年：2016

7.New telmisartan-derived PPARγ agonists: Impact of the 3D-binding mode on the pharmacological profile

作者：Victoria Obermoser^a ; Margarethe E. Urban^b ; Manuela S. Murgueitio^c ; Gerhard Wolber^c ; Ulrich Kintscher^d ; Ronald Gust^a ; ^{ronald.gust@uibk.ac.at" class="auth_mail" title="E-mail the corresponding author}

关键词：PPARγ ; Transactivation ; Cytotoxicity ; Binding mode ; Molecular modeling

刊名：European Journal of Medicinal Chemistry

出版年：2016

8.Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT₃ receptors

作者：Agnes Gasiorek^a ; Sarah M. Trattnig^a ; Philip K. Ahring^b ; ¹ ; Uffe Kristiansen^a ; Bente Frø ; lund^a ; Kristen Frederiksen^c ; Anders A. Jensen^a ; ^{aaj@sund.ku.dk" class="auth_mail" title="E-mail the corresponding author}

关键词：Cys-loop receptor ; 5-HT3 receptor ; Allosteric agonist ; Allosteric modulation ; Ago-PAM ; TMPPAA

刊名：Biochemical Pharmacology

出版年：2016

9.Targeting Estrogen Receptor Beta in a Phase 2 Study of High-Dose Estradiol in Metastatic Triple-Negative Breast Cancer: A Wisconsin Oncology Network Study

作者：Kari B. Wisinski¹ ; ² ; ^{kbwisinski@medicine.wisc.edu" class="auth_mail" title="E-mail the corresponding author} ; Wei Xu¹ ; ³ ; Amye J. Tevaarwerk¹ ; ² ; Sandeep Saha⁴ ; KyungMann Kim¹ ; ⁴ ; Anne Traynor¹ ; ² ; Leah Dietrich⁵ ; Robert Hegeman¹ ; ² ; Dhimant Patel⁶ ; Jules Blank⁷ ; Josephine Harter¹ ; ⁸ ; Mark E. Burkard¹ ; ²

关键词：Estradiol ; Estrogen receptor beta ; Triple-negative breast cancer

刊名：Clinical Breast Cancer

出版年：2016

10.The antipsychotic aripiprazole induces antinociceptive effects: Possible role of peripheral dopamine D₂ and serotonin 5-HT_1A receptors

作者：Ana F. Almeida-Santos¹ ; Renata C.M. Ferreira¹ ; Igor D. Duarte ; Daniele C. Aguiar ; Thiago R.L. Romero ; ^{thiromero@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Fabricio A. Moreira ; ^{fabriciomoreira@icb.ufmg.br" class="auth_mail" title="E-mail the corresponding author}

关键词：Partial agonist ; Nociception ; Analgesia ; Dopamine ; Serotonin

刊名：European Journal of Pharmacology

出版年：2015

按检索点细分(255)

题名(26)

关键词(23)

文摘(206)

按出版年细分(255)

2027年及以后(7)

2017年(1)

2016年(8)

2015年(6)

2013年(14)

2012年(12)

2011年(11)

2010年(19)

2009年(20)

2008年(16)

2007年(9)

2006年(14)

2005年(8)

2004年(11)

2003年(16)

2002年(6)

2001年(4)

2000年(12)

2000年及以前(61)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700