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Elsevier电子期刊(253)

在“Elsevier电子期刊”中，命中：253条，耗时：小于0.01 秒

在所有数据库中总计命中：380条

1.Novel triclabendazole prodrug: A highly water soluble alternative for the treatment of fasciolosis

作者：Miguel Flores-Ramos^a ; Froylá ; n Ibarra-Velarde^b ; Helgi Jung-Cook^a ; Alicia Herná ; ndez-Campos^a ; Yolanda Vera-Montenegro^b ; Rafael Castillo^a ; ^{rafaelc@unam.mx}

关键词：Triclabendazole ; Fasciola hepatica ; Prodrug ; Benzimidazole ; Phosphonooxymethyl ; Fasciolicidal activity

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Novel prodrugs with a spontaneous cleavable guanidine moiety

作者：Yoshio Hamada ; ^{pynden@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Guanidino acid ; Phenytoin ; Prodrug ; Quinine ; Sulfa drug

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.Modulating lipophilicity of rohitukine via prodrug approach: Preparation, characterization, and in vitro enzymatic hydrolysis in biorelevant media

作者：Vikas Kumar^a ; ^b ; Sonali S. Bharate^a ; ^{sonalibharate@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ram A. Vishwakarma^b ; ^c ; ^{ram@iiim.ac.in" class="auth_mail" title="E-mail the corresponding author}

关键词：log D ; distribution coefficient ; log P ; partition coefficient ; NCEs ; new chemical entities ; PBS ; phosphate buffer saline ; SGF ; Simulated gastric fluid ; SIF ; Simulated intestinal fluid ; RP-HPLC ; reverse-phase high-performance liquid chromatography ; tR ; retention time ; UV ; ultraviolet ; HMBC ; Heteronuclear Multiple Bond Correlation ; GI50 ; Concentration for 50% growth inhibition

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

4.Activation of multiple chemotherapeutic prodrugs by the natural enzymolome of tumour-localised probiotic bacteria

作者：Panos Lehouritis^a ; ¹ ; Michael Stanton^a ; ¹ ; Florence O. McCarthy^b ; Matthieu Jeavons^a ; Mark Tangney^a ; ^{m.tangney@ucc.ie" class="auth_mail" title="E-mail the corresponding author}

关键词：Cancer ; Therapy ; Targeting ; Chemotherapy ; GDEPT

刊名：Journal of Controlled Release

出版年：2016

5.Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapy

作者：Alexandra M. Mowday^a ; Amir Ashoorzadeh^a ; Elsie M. Williams^b ; ¹ ; Janine N. Copp^b ; ² ; Shevan Silva^a ; Matthew R. Bull^a ; Maria R. Abbattista^a ; Robert F. Anderson^a ; ^c ; Jack U. Flanagan^a ; ^c ; Christopher P. Guise^a ; ^c ; David F. Ackerley^b ; ^c ; Jeff B. Smaill^a ; ^c ; Adam V. Patterson^a ; ^c ; ^{a.patterson@auckland.ac.nz" class="auth_mail" title="E-mail the corresponding author}

关键词：PR-104 (PubChem CID ; 11455973) ; PR-104A (PubChem CID ; 9848786) ; SN34037 (PubChem CID ; 73671441) ; SN34507 (PubChem CID ; 90043967) ; SN35539 (PubChem CID ; 90043246)

刊名：Biochemical Pharmacology

出版年：2016

6.Simultaneous determination of curcumin diethyl disuccinate and its active metabolite curcumin in rat plasma by LC-MS/MS: Application of esterase inhibitors in the stabilization of an ester-containing prodrug

作者：Pahweenvaj Ratnatilaka Na Bhuket^a ; Nuansri Niwattisaiwong^b ; ^c ; Patanachai Limpikirati^b ; Phisit Khemawoot^d ; Pasarapa Towiwat^d ; Boonsri Ongpipattanakul^e ; ^f ; Pornchai Rojsitthisak^b ; ^{pornchai.r@chula.ac.th" class="auth_mail" title="E-mail the corresponding author}

关键词：CDD ; curcumin diethyl disuccinate ; CUR ; curcumin ; DMC ; dimethylcurcumin ; IS ; internal standard

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

7.Hyaluronic acid liposomal gel sustains delivery of a corticoid to the inner ear

关键词：Chol ; cholesterol ; DSPE-PEG2000 ; 1 ; 2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy-poly-(ethyleneglycol)-2000] ; Dex ; dexamethasone ; DexP ; dexamethasone phosphate ; DLS ; dynamic light scattering ; EPC ; egg phosphatidylcholine ; Flu ; flumethasone ; HA ; hyaluronic acid ; Lip ; liposomes ; LC&ndash ; MS ; liquid chromatography coupled to mass spectroscopy ; PE ; phosphatidylethanolamine ; Rh ; rhodamine ; RW ; round window

刊名：Journal of Controlled Release

出版年：2016

8.The role of the equatorial ligands for the redox behavior, mode of cellular accumulation and cytotoxicity of platinum(IV) prodrugs

作者：Simone Gö ; schl^a ; Hristo P. Varbanov^a ; ^b ; ^{hristo.varbanov@univie.ac.at" class="auth_mail" title="E-mail the corresponding author} ; Sarah Theiner^a ; ^c ; Michael A. Jakupec^a ; ^c ; ^{michael.jakupec@univie.ac.at" class="auth_mail" title="E-mail the corresponding author} ; Markus Galanski^a ; Bernhard K. Keppler^a ; ^c

关键词：AA ; ascorbic acid ; DNA ; deoxyribonucleic acid ; FBS ; fetal bovine serum ; GSH ; glutathione ; ICP-MS ; inductively coupled plasma mass spectrometry ; MEM ; minimum essential medium ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; NMR ; nuclear magnetic resonance ; oc ; open circular ; PBS ; Dulbecco's phosphate-buffered saline ; ROS ; reactive oxygen species ; RPMI ; Roswell Park Memorial Institute medium ; sc ; supercoiled ; SD ; standard deviation ; TBE ; Tris-Borate-EDTA ; TE ; Tris-EDTA

刊名：Journal of Inorganic Biochemistry

出版年：2016

9.Terlipressin, a vasoactive prodrug recommended in hepatorenal syndrome, is an agonist of human V1, V2 and V1B receptors: Implications for its safety profile

关键词：Terlipressin ; PubChem CID ; 72081 ; [Arginine8]Vasopressin ; PubChem CID ; 90488786 ; [Lysine8]Vasopressin ; PubChem CID ; 90488785 ; SR49059 ; PubChem CID ; 60943

刊名：Pharmacological Research

出版年：2016

10.The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts

作者：Tracy E. Strecker^a ; ¹ ; Samuel O. Odutola^b ; ¹ ; Ramona Lopez^c ; Morgan S. Cooper^a ; Justin K. Tidmore^a ; Amanda K. Charlton-Sevcik^a ; Li Li^c ; Matthew T. MacDonough^a ; Mallinath B. Hadimani^a ; Anjan Ghatak^a ; ^&dagger ; ; Li Liu^c ; David J. Chaplin^d ; Ralph P. Mason^c ; Kevin G. Pinney^a ; ^b ; Mary Lynn Trawick^a ; ^b ; ^{mary_lynn_trawick@baylor.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ANOVA ; analysis of variance ; BLI ; bioluminescence imaging ; CA4 ; combretastatin A-4 ; CA4P ; combretastatin A-4 phosphate ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; DMSO ; dimethyl sulfoxide ; DTT ; dithiothreitol ; FAK ; focal adhesion kinase ; FDA ; Federal Drug Administration ; FITC ; fluorescein isothiocyanate ; GI50 ; median growth inhibitory concentration ; HRP ; horseradish peroxidase ; HUVEC ; human umbilical vein endothelial cells ; MLC ; myosin light chain ; NMII ; non-muscle myosin II ; OXi8006 ; 2-(3&prime

刊名：Cancer Letters

出版年：2015

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