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1.Chemoenzymatic synthesis of fluorogenic phospholipids and evaluation in assays of phospholipases A, C and D

作者：Mathilde S. Piel^a ; Gü ; nther H.J. Peters^b ; Jesper Brask^a ; ^{jebk@novozymes.com}

关键词：Assay ; Phospholipase ; Fluorescence ; FRET ; Synthetic substrate ; Biocatalysis

刊名：Chemistry and Physics of Lipids

出版年：2017

2.Activity-based targeting of secretory phospholipase A₂ enzymes: A fatty-acid-binding-protein assisted approach

作者：Amir Keshavarz^a ; ^{akeshavarz@ucmerced.edu} ; ^{amir.keshavarz.487@my.csun.edu} ; Ligia Zelaya^a ; Jasmeet Singh^b ; Radha Ranganathan^b ; ^{radha.ranganathan@csun.edu} ; Joseph Hajdu^a ; ¹

关键词：Phospholipid syntheses ; Fluorescent phospholipid substrates ; Phospholipase A2 assay

刊名：Chemistry and Physics of Lipids

出版年：2017

3.The potential of aqueous extracts of Bellucia dichotoma Cogn. (Melastomataceae) to inhibit the biological activities of Bothrops atrox venom: A comparison of specimens collected in the states of Pará and Amazonas, Brazil

作者：Valé ; ria Mourã ; o de Moura^a ; ^b ; ^{mouraovm@yahoo.com.br} ; Luana Yamille Andrade de Souza^b ; Noranathan da Costa Guimarã ; es^c ; Ilia Gilmara Carvalho dos Santos^a ; ^b ; Patrí ; cia Danielle Oliveira de Almeida^d ; Ricardo Bezerra de Oliveira^c ; Rosa Helena Veras Mourã ; o^c ; Maria Cristina Dos-Santos^a ; ^b

关键词：Bellucia dichotoma ; Snakebite ; Anti-snakebite plants ; Folk medicine ; Bothrops

刊名：Journal of Ethnopharmacology

出版年：2017

4.Advantages of the lipoprotein-associated phospholipase A2 activity assay

作者：Leslie J. Donato^a ; ^{Donato.leslie@mayo.edu" class="auth_mail" title="E-mail the corresponding author} ; Jeffrey W. Meeusen^a ; Heidi Callanan^a ; Amy K. Saenger^c ; Allan S. Jaffe^a ; ^b

关键词：Biomarkers ; Lipoprotein-associated phospholipase A2 ; Lp-PLA2 ; PLAC activity ; Platelet activating factor acetylhydrolase ; Assay validation

刊名：Clinical Biochemistry

出版年：2016

5.Advantages of the lipoprotein-associated phospholipase A2 activity assay

作者：Leslie J. Donato^a ; ^{Donato.leslie@mayo.edu" class="auth_mail" title="E-mail the corresponding author} ; Jeffrey W. Meeusen^a ; Heidi Callanan^a ; Amy K. Saenger^c ; Allan S. Jaffe^a ; ^b

关键词：Biomarkers ; Lipoprotein-associated phospholipase A2 ; Lp-PLA2 ; PLAC activity ; Platelet activating factor acetylhydrolase ; Assay validation

刊名：Clinical Biochemistry

出版年：2016

6.Evaluation of recombinant enzyme calibration to harmonize lipoprotein-associated phospholipase A₂ activity results between instruments

作者：Mary Jane Cerelli^a ; Karen Grimm^a ; Xiaozhu Duan^a ; Edie Mulberg^a ; Maria Jalilie^a ; Phillip Sekella^a ; Marta Payes^a ; Heather Cox^a ; Kenneth E. Blick^b ; Kenneth C. Fang^a ; Emi Zychlinsky^a ; ^{ezychlinsky@diadexus.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ASA ; acetylsalicylic acid ; CHD ; coronary heart disease ; CVD ; cardiovascular disease ; CV ; coefficient of variation ; ELISA ; enzyme-linked immunosorbent assay ; LOB ; limit of blank ; LOD ; limit of detection ; LOQ ; limit of quantitation ; Lp-PLA2 ; lipoprotein-associated phospholipase A2 ; rLp-PLA2 ; recombinant Lp-PLA2

刊名：Clinical Biochemistry

出版年：2016

7.UCN enhances TGF-beta-mediated mitoinhibition of VSMCs via counteracting TGF-beta-induced cPLA2 expression and activation

作者：Chao Zhu ; Changchun Cao ; Xiaofei Wang ; Jie Yuan ; Lai Jin ; Shengnan Li ; ^{snli@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Ast ; astressin ; cPLA2 ; cytosolic phospholipase A2 ; CRF ; corticotrophin-releasing factor ; CRFR ; corticotrophin-releasing factor receptor ; PYR ; pyrrophenone ; UCN ; urocortin ; mitoinhibition ; mitosis inhibition

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

8.Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A₂

作者：Varnavas D. Mouchlis^a ; ^{vmouchlis@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Christophe Morisseau^b ; Bruce D. Hammock^b ; Sheng Li^c ; J. Andrew McCammon^a ; ^{jmccammon@ucsd.edu" class="auth_mail" title="E-mail the corresponding author} ; Edward A. Dennis^a ; ^{edennis@ucsd.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Phospholipase A2 ; Trifluoromethylketones ; Thioether ; DXMS ; Docking ; MD simulations ; Structure&ndash ; activity relationship

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

9.Promoting effect of adipocytokine, apelin, on hepatic injury in caerulein-induced acute pancreatitis in rats: Apelin on AP-induced hepatic injury

作者：Marwa N. Emam ; ^{maroo_drmaroo@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Rehab E. Abo El gheit

关键词：Acute pancreatitis ; Liver injury ; Apelin-13 ; Caerulein ; Phospholipase A2 ; Amylase

刊名：Alexandria Journal of Medicine

出版年：2016

10.BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly

关键词：5-LO ; 5-lipoxygenase ; AA ; arachidonic acid ; COX ; cyclooxygenase ; cPLA2 ; cytosolic phospholipase A2 ; FLAP ; 5-lipoxygenase-activating protein ; fMLP ; N-formyl-methionyl-leucyl-phenylalanine ; H(P)ETE ; hydro(pero)oxyeicosatetraenoic acid ; HHT ; hydroxyheptadecatrienoic acid ; IL ; interleukin ; LPS ; lipopolysaccharide ; LT ; leukotriene ; mPGES-1 ; microsomal prostaglandin E2 synthase 1 ; MPO ; myeloperoxidase ; PG ; phosphate-buffered saline plus 1 ; mg/ml glucose ; PGC ; phosphate-buffered saline plus 1

刊名：Biochemical Pharmacology

出版年：2016

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