搜索页_+Predictive+toxicology

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在“Elsevier电子期刊”中，命中：726条，耗时：0.0229891 秒

在所有数据库中总计命中：979条

1.CORAL: Binary classifications (active/inactive) for drug-induced liver injury

作者：Alla P. Toropova ; ^{alla.toropova@marionegri.it} ; Andrey A. Toropov

关键词：QSAR ; Drug-induced liver injury ; Monte Carlo method ; Predictive toxicology ; Risk assessment

刊名：Toxicology Letters

出版年：2017

2.Different end-points to assess effects in systemic lupus erythematosus patients exposed to pesticide mixtures

作者：M.F. Simoniello^a ; ^{fersimoniello@yahoo.com.ar} ; L. Contini^b ; E. Benavente^c ; C. Mastandrea^a ; S. Roverano^c ; S. Paira^c

关键词：Systemic lupus erythematosus ; Pesticides ; Oxidative DNA damage

刊名：Toxicology

出版年：2017

3.Screening, verification, and analysis of biomarkers for drug-induced cardiac toxicity in vitro based on RTCA coupled with PCR Array technology

作者：Lu Zhang^a ; ^b ; ¹ ; Meng-Xi Xu^b ; ¹ ; Qing-Sheng Yin^b ; Cai-Ying Zhu^a ; Xue-Lian Cheng^a ; Yi-Ran Ren^a ; Peng-Wei Zhuang^b ; ^{zhuangpengwei@163.com} ; Yan-Jun Zhang^b ; ^{zyjsunye@163.com}

关键词：RTCA ; Real Time Cell Analysis ; IPA ; Ingenuity Pathway Analysis ; FBS ; fetal bovine serum ; CCK8 ; Cell Counting Kit 8 ; DMEM ; Dulbecco&rsquo ; s modified eagle medium ; LDH ; lactate dehydrogenase ; DOX ; doxorubicin ; ISO ; isoprenaline ; OUA ; ouabain ; Vc ; Vitamin C ; PAR ; paracetamol ; MON ; monocrotaline ; ETI ; etimicin ; GEN ; gentamicin ; DAU ; daunorubicin ; MET ; metoprolol ; ACO ; aconitine ; RSD ; relative standard deviation

刊名：Toxicology Letters

出版年：2017

4.Response of oxidative stress transcripts in the brain of wild yellow perch (Perca flavescens) exposed to an environmental gradient of methylmercury

作者：Stephanie D. Graves^a ; ^{s.graves@usask.ca} ; Karen A. Kidd^a ; Katharina L. Batchelar^a ; Andrew M. Cowie^a ; Nelson J. O'Driscoll^b ; Christopher J. Martyniuk^a ; ^c

关键词：Oxidative stress ; Metals ; Fish ; Gene expression ; Methyl mercury

刊名：Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology

出版年：2017

5.Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system

作者：A. Dash^a ; ¹ ; R.A. Figler^a ; ¹ ; B.R. Blackman^b ; S. Marukian^a ; M.S. Collado^a ; M.J. Lawson^a ; S.A. Hoang^a ; A.J. Mackey^a ; D. Manka^a ; B.K. Cole^a ; R.E. Feaver^a ; A.J. Sanyal^c ; B.R. Wamhoff^a ; ^{Wamhoff@HemoShear.com}

关键词：NASH ; nonalcoholic steatohepatitis ; NAFD ; nonalcoholic fatty liver disease ; FXR ; farnesoid X receptor ; FGF19 ; fibroblast growth factor ; DMSO ; dimethyl sulfoxide ; CYP ; cytochrome P450

刊名：Toxicology in Vitro

出版年：2017

6.Prevalidation trial for a novel in vitro eye irritation test using the reconstructed human cornea-like epithelial model, MCTT HCE™

作者：Hyeri Yang^a ; Da-eun Kim^a ; Won-Hee Jang^b ; Susun An^b ; Sun-A Cho^b ; Mi-Sook Jung^c ; Ji Eun Lee^c ; Kyung-Wook Yeo^d ; Sang Bum Koh^d ; Tae-Cheon Jeong^e ; Mi-Jeong Kang^e ; Young-Jin Chun^f ; Su-Hyon Lee^g ; Kyung-Min Lim^a ; ^{kmlim@ewha.ac.kr} ; SeungJin Bae^a ; ^{sjbae@ewha.ac.kr}

关键词：EIT ; eye irritation test ; RhCE ; reconstructed human cornea-like epithelium ; OECD TG ; OECD Test guidelines ; GHS ; global harmonization system ; WL/BL ; within-/between-laboratory ; ROC ; receiver operating characteristics ; SD ; standard deviation ; AUC ; area under curve ; ICC ; intra-class correlation ; PS ; performance standard

刊名：Toxicology in Vitro

出版年：2017

7.Toxicologic effects of 28-day dietary exposure to the flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)-cyclohexane (TBECH) in F344 rats

作者：Ivan H.A. Curran^a ; ^{Ivan.Curran@Canada.ca} ; Virginia Liston^a ; André ; e Nunnikhoven^a ; Don Caldwell^b ; Matthew J.S. Scuby^c ; Peter Pantazopoulos^c ; Dorothea F.K. Rawn^d ; Laurie Coady^a ; Cheryl Armstrong^a ; David E. Lefebvre^a ; Genevieve S. Bondy^a

关键词：1 ; 2-dibromo-4-(1 ; 2-dibromoethyl)-cyclohexane ; TBECH ; Rat ; Endocrine ; Kidney

刊名：Toxicology

出版年：2017

8.Photosynthetic efficiency predicts toxic effects of metal nanomaterials in phytoplankton

作者：Robert J. Miller^a ; ¹ ; ^{miller@msi.ucsb.edu} ; Erik B. Muller^a ; ¹ ; Bryan Cole^b ; ¹ ; Tyronne Martin^c ; Roger Nisbet^d ; Gretchen K. Bielmyer-Fraser^e ; Tayler A. Jarvis^f ; Arturo A. Keller^a ; Gary Cherr^b ; ^g ; Hunter S. Lenihan^c

关键词：High throughput screening ; Dynamic energy budget modeling ; Plankton ; Ecotoxicity ; Metallic nanoparticles ; Marine ecology

刊名：Aquatic Toxicology

出版年：2017

9.Assessing the predictive value of the rodent neurofunctional assessment for commonly reported adverse events in phase I clinical trials

作者：Andy N. Mead^a ; ¹ ; Hamid R. Amouzadeh^b ; Kathryn Chapman^c ; Lorna Ewart^d ; Alessandra Giarola^e ; Samuel J. Jackson^c ; ^{sam.jackson@nc3rs.org.uk" class="auth_mail" title="E-mail the corresponding author} ; Philip Jarvis^f ; Pierre Jordaan^f ; Will Redfern^g ; Martin Traebert^h ; Jean-Pierre Valentinⁱ ; ² ; Hugo M. Vargas^b

关键词：Adverse events ; Central nervous system ; First-in-human ; Functional observational battery ; Methods ; Neurobehavioural assessment ; Predictive value ; Translation

刊名：Regulatory Toxicology and Pharmacology

出版年：2016

10.In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines

作者：Martin Roursgaard^a ; ^{mwro@sund.ku.dk" class="auth_mail" title="E-mail the corresponding author} ; Kristina Bram Knudsen^a ; ^b ; ^c ; Helle Northeved^c ; Mikael Persson^c ; Tina Christensen^c ; Pramod E.K. Kumar^d ; Anders Permin^e ; Thomas L. Andresen^d ; Torben Gjetting^d ; Jens Lykkesfeldt^a ; Lise K. Vesterdal^a ; Steffen Loft^a ; Peter Mø ; ller^a

关键词：Drug delivery systems ; Liposomes ; Micelles ; In vitro toxicology ; Nanomedicine ; Hepatocytes ; Lung epithelial cells ; Comet assay

刊名：Toxicology in Vitro

出版年：2016

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