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1.Apocynin and enzymatically modified isoquercitrin suppress the expression of a NADPH oxidase subunit p22phox in steatosis-related preneoplastic liver foci of rats

作者：Toshinori Yoshida^a ; ^{yoshida7@cc.tuat.ac.jp} ; Hirotada Murayama^a ; Masahi Kawashima^a ; Rei Nagahara^a ; Yumi Kangawa^a ; Sayaka Mizukami^a ; ^b ; Masayoshi Kimura^a ; ^b ; Hajime Abe^a ; ^b ; Shim-mo Hayashi^c ; Makoto Shibutani^a

关键词：NADPH oxidase ; Preneoplastic liver cell lesions ; Two-stage hepatocarcinogenesis model ; High fat diet ; Apocynin ; Enzymatically modified isoquercetin

刊名：Experimental and Toxicologic Pathology

出版年：2017

2.Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions

作者：Clara Lubeseder-Martellato^a ; ^{clara.lubeseder-martellato@tum.de} ; Katharina Alexandrow^a ; Ana Hidalgo-Sastre^a ; Irina Heid^b ; Sophie Luise Boos^a ; ^c ; Thomas Briel^a ; Roland M. Schmid^a ; ^c ; Jens T. Siveke^a ; ^c ; ^d ; ^{j.siveke@dkfz.de}

关键词：Oncogenic KRas ; Fluid-phase endocytosis ; Pancreatic ductal adenocarcinoma (PDAC) ; Acinar-to-ductal metaplasia (ADM) ; Acinar epithelial explants ; Neural-Wiskott-Aldrich syndrome protein (N-WASP) ; Mice models

刊名：EBioMedicine

出版年：2017

3.Identification of epigenetically downregulated Tmem70 and Ube2e2 in rat liver after 28-day treatment with hepatocarcinogenic thioacetamide showing gene product downregulation in hepatocellular preneoplastic and neoplastic lesions produced by tumor promotion

作者：Sayaka Mizukami^a ; ^b ; ^{smizuka@cc.tuat.ac.jp} ; Atsunori Yafune^a ; ^{yafune-atsunori@bozo.co.jp} ; Yousuke Watanabe^a ; ^b ; ^{ywatana@cc.tuat.ac.jp} ; Kota Nakajima^a ; ^b ; ^{knakaji@m2.tuat.ac.jp} ; Meilan Jin^c ; ^{meilan0622@swu.edu.cn} ; Toshinori Yoshida^a ; ^{yoshida7@cc.tuat.ac.jp} ; Makoto Shibutani^a ; ^{mshibuta@cc.tuat.ac.jp}

关键词：ATP ; adenosine triphosphate ; BNF ; β-naphthoflavone ; CGI ; CpG island ; CT ; threshold cycle ; DEN ; N-diethylnitrosamine ; FB ; fenbendazole ; gDNA ; genomic DNA ; GST-P ; glutathione S-transferase placental form ; HIST1H2AA ; histone cluster 1 H2A family member a ; IP DNA ; immunoprecipitated DNA ; PB ; phenobarbital ; PBO ; piperonyl butoxide ; PCNA ; proliferating cell nuclear antigen ; RT-PCR ; reverse-transcription polymerase chain reaction ; SLK ; STE20-like kinase ; TAA ; thioacetamide ; TMEM70 ; transmembrane protei

刊名：Toxicology Letters

出版年：2017

4.Laryngeal preneoplastic lesions and cancer: challenging diagnosis. Qualitative literature review and meta-analysis.

作者：Giuditta Mannelli ; MD^a ; ^{mannelli.giuditta@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Lorenzo Cecconi ; PhD^b ; Oreste Gallo ; MD^a

关键词：laryngeal cancer ; laryngeal lesions diagnosis ; laryngeal precancerosis ; diagnostic imaging ; meta-analysis ; systematic review

刊名：Critical Reviews in Oncology and Hematology

出版年：2016

5.Dietary zinc deficiency predisposes mice to the development of preneoplastic lesions in chemically-induced hepatocarcinogenesis

作者：Guilherme Ribeiro Romualdo^a ; Renata Leme Goto^b ; Ana Angé ; lica Henrique Fernandes^c ; Bruno Cogliati^d ; Luis Fernando Barbisan^b ; ^{barbisan@ibb.unesp.br" class="auth_mail" title="E-mail the corresponding author}

关键词：Antioxidant defense ; Diethylnitrosamine ; Mouse hepatocarcinogenesis ; Preneoplasia ; Zinc deficiency ; Zinc supplementation

刊名：Food and Chemical Toxicology

出版年：2016

6.miR-21, miR-155, miR-192, and miR-375 Deregulations Related to NF-kappaB Activation in Gastroduodenal Fluid-Induced Early Preneoplastic Lesions of Laryngeal Mucosa In Vivo

作者：Clarence T. Sasaki ; ^{clarence.sasaki@yale.edu" class="auth_mail" title="E-mail the corresponding author} ; Dimitra P. Vageli

刊名：Neoplasia

出版年：2016

7.M1-/M2-macrophages contribute to the development of GST-P-positive preneoplastic lesions in chemically-induced rat cirrhosis

作者：Kavindra Kumara Wijesundera¹ ; Takeshi Izawa¹ ; Anusha Hemamali Tennakoon ; Hossain M. Golbar ; Miyuu Tanaka ; Mitsuru Kuwamura ; Jyoji Yamate

关键词：Cirrhosis ; Glutathione-S-transferase placental form ; Macrophage polarization ; Preneoplastic lesion

刊名：Experimental and Toxicologic Pathology

出版年：2015

8.Seminal epithelium in prostate biopsy can mimic malignant and premalignant prostatic lesions

作者：J. Arista-Nasr^a ; A. Trolle-Silva^a ; E. Aguilar-Ayala^b ; B. Martí ; nez-Bení ; tez^a ; ^{brauliomb77@yahoo.com.mx" class="auth_mail" title="E-mail the corresponding author}

关键词：Prostate ; Seminal epithelium ; Puncture biopsy ; Prostatic intraepithelial neoplasia ; Atypical small acinar proliferation ; False positive results

刊名：Actas Urológicas Espa?olas (English Edition)

出版年：2016

9.The impact of BMI on early colorectal neoplastic lesions and the role of endoscopic diagnosis:. An Italian observational study

关键词：Colorectal cancer ; Body mass index ; Endoscopy ; Polyps

刊名：International Journal of Surgery

出版年：2016

10.Early signet ring cell carcinoma arising from colonic adenoma: the molecular profiling supports the adenoma-carcinoma sequence

作者：Alberto Bellan ; MD^a ; ¹ ; Rocco Cappellesso ; MD^a ; ¹ ; Marcello Lo Mele ; MD^a ; Laura Peraro ; MD^b ; Laura Balsamo ; BD^a ; Cristiano Lanza ; BD^a ; Matteo Fassan ; MD ; PhD^a ; ^{matteo.fassan@unipd.it" class="auth_mail" title="E-mail the corresponding author} ; Massimo Rugge ; MD ; FACG^a

关键词：Signet ring cell carcinoma ; Colorectal adenocarcinoma ; Molecular profiling ; Preneoplastic lesions ; KRAS

刊名：Human Pathology

出版年：2016

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