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在“Elsevier电子期刊”中，命中：703条，耗时：0.054973 秒

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1.Stabilized and enhanced CYP450 enzyme activity in cultured human primary hepatocytes is conferred by reprohp medium

作者：Paul E. Cizdziel¹ ; Misturu Inamura¹ ; Rina Akihira¹ ; Zachary Yu-Ching Lin¹ ; Kenichi Tamura¹ ; Tomohisa Watanabe¹ ; Shunsuke Yoshida¹ ; Tohru Kiyono²

刊名：Drug Metabolism and Pharmacokinetics

出版年：2017

2.Antioxidant properties of tea blunt ROS-dependent lipogenesis: beneficial effect on hepatic steatosis in a high fat-high sucrose diet NAFLD obese rat model

作者：Laura Braud^a ; ^{lbraud01@gmail.com} ; Sylvain Battault^b ; Gré ; gory Meyer^b ; Alessandro Nascimento^b ; Sandrine Gaillard^c ; Georges de Sousa^d ; Roger Rahmani^d ; Catherine Riva^b ; Martine Armand^e ; Jean-Michel Maixent^a ; ¹ ; Cyril Reboul^b ; ¹

关键词：NAFLD ; Camellia sinensis ; Antilipogenesis ; Antioxidant ; Mitochondrial ROS ; Obesogenic diet

刊名：The Journal of Nutritional Biochemistry

出版年：2017

3.Prazosin-stimulated release of hepatic triacylglyceride lipase from primary cultured rat hepatocytes is involved in the regulation of cAMP-dependent protein kinase through activation of the Ca²⁺/calmodulin-dependent protein kinase-II

作者：Tetsuya Nakamura ; ^{tnaka@fupharm.fukuyama-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Jun Kamishikiryo ; Tetsuo Morita

关键词：Prazosin ; Hepatic lipase ; Calcium/calmodulin-dependent protein kinase II ; Primary cultured rat hepatocytes

刊名：Pharmacological Reports

出版年：2016

4.Protective effect of Cistanchis A on ethanol-induced damage in primary cultured mouse hepatocytes

作者：Huiying Luo^a ; ^b ; ^{louria@126.com" class="auth_mail" title="E-mail the corresponding author} ; Rongrong Cao^a ; Lijuan Wang^a ; ^b ; Lijuan Zhu^a ; ^b

关键词：Cistanoside A ; alcohol damage ; primary cultured hepatocytes ; apoptosis

刊名：Biomedicine & Pharmacotherapy

出版年：2016

5.Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles

作者：Jie Zhang^a ; Utkarsh Doshi^b ; Ayako Suzuki^c ; Ching-Wei Chang^a ; Jü ; rgen Borlak^d ; ¹ ; Albert P. Li^b ; ¹ ; ^{lialbert@invitroadmet.com" class="auth_mail" title="E-mail the corresponding author} ; Weida Tong^a ; ¹ ; ^{Weida.Tong@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：Drug induced liver injury ; Acute liver failure ; Oxidative stress ; In vitro toxicity testing ; Human hepatocytes ; Drug development

刊名：Chemico-Biological Interactions

出版年：2016

6.Addition of Dexamethasone Alters the Bile Acid Composition by Inducing CYP8B1 in Primary Cultures of Human Hepatocytes

作者：Lisa-Mari Mö ; rk^* ; ^{lisa-mari.mork@ki.se" class="auth_mail" title="E-mail the corresponding author} ; Stephen C. Strom^&dagger ; ; Agneta Mode^&Dagger ; ; Ewa C.S. Ellis^*

关键词：BSEP ; bile salt export pump ; CA ; cholic acid ; CDCA ; chenodeoxycholic acid ; CYP7A1 ; cholesterol 7α-hydroxylase ; CYP8B1 ; sterol 12α-hydroxylase ; CYP27A1 ; sterol 27α-hydroxylase ; FXR ; farnesoid X receptor ; G6Pase ; glucose-6-phosphatase ; GR ; glucocorticoid receptor ; NTCP ; Na+-taurocholate cotransporting polypeptide ; PXR ; pregnane X receptor ; ROR ; retinoid-related orphan receptor

刊名：Journal of Clinical and Experimental Hepatology

出版年：2016

7.Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats

关键词：DILI ; drug-induced liver injury ; NPC ; non-parenchymal cells ; 2D-sw ; 2D-sandwich ; SM ; safety margin ; MT ; microtissue ; TC ; training compound

刊名：Toxicology Letters

出版年：2016

8.In vitro effects of somatostatin on the growth hormone-insulin-like growth factor axis in orange-spotted grouper (Epinephelus coioides)

作者：Bin Wang ; Jirong Jia ; Guokun Yang ; Jingkai Qin ; Cong Zhang ; Qiuping Zhang ; Caiyun Sun ; Wensheng Li ; ^{lsslws@mail.sysu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Somatostatin ; Growth hormone ; Growth hormone receptor ; Insulin-like growth factor ; Grouper ; Primary cell cultures

刊名：General and Comparative Endocrinology

出版年：2016

9.Constrained spheroids for prolonged hepatocyte culture

作者：Wen Hao Tong^a ; ^b ; ^c ; Yu Fang^a ; ^b ; ^c ; Jie Yan^a ; ^c ; ^g ; Xin Hong^c ; Nisha Hari Singh^a ; Shu Rui Wang^d ; Bramasta Nugraha^a ; ^b ; ^e ; ^f ; Lei Xia^c ; Eliza Li Shan Fong^c ; Ciprian Iliescu^a ; ^{ciliescu@ibn.a-star.edu.sg" class="auth_mail" title="E-mail the corresponding author} ; Hanry Yu^a ; ^b ; ^c ; ^g ; ^h ; ⁱ ; ^{hanry_yu@nuhs.edu.sg" class="auth_mail" title="E-mail the corresponding author}

关键词：Hepatocytes ; Spheroids ; Liver ; Perfusion ; Drug testing

刊名：Biomaterials

出版年：2016

10.The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4

关键词：FLU ; flutamide ; AhR ; aryl hydrocarbon receptor ; ARNT ; aryl hydrocarbon receptor nuclear translocator ; CYP ; cytochrome P450 ; TCDD ; 237 ; 8-tetrachlorodibenzo-p-dioxin ; 3-MC ; 3-methylcholanthrene ; ABCC4 ; ATP-binding cassette sub-family C member 4 ; MRP4 ; multidrug resistance-associated protein 4 ; PAS ; Per-ARNT-Sim ; DRE ; dioxin-responsive elements ; LBD ; ligand binding domain ; ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; ALP ; alkaline phosphatase ; PXR ; pregnane X receptor ; CAR ; con

刊名：Biochemical Pharmacology

出版年：2016

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