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Elsevier电子期刊(39)

在“Elsevier电子期刊”中，命中：39条，耗时：小于0.01 秒

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1.Fluoroquinolones stimulate the DNA cleavage activity of topoisomerase IV by promoting the binding of Mg^{2 +} to the second metal binding site

作者：Lisa M. Oppegard^a ; ¹ ; ^{brown235@umn.edu" class="auth_mail" title="E-mail the corresponding author} ; Heidi A. Schwanz^b ; ² ; ^{heidiannschwanz@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Tyrell R. Towle^b ; ³ ; ^{tyrelltowle@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Robert J. Kerns^b ; ^{robert-kerns@uiowa.edu" class="auth_mail" title="E-mail the corresponding author} ; Hiroshi Hiasa^a ; ^{hiasa001@umn.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Divalent metal ion ; DNA gyrase ; Fluoroquinolone ; Quinazolinedione ; Topoisomerase IV

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2016

2.Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics

作者：Giovanna Sociali^a ; ¹ ; Lauretta Galeno^b ; ¹ ; Marco Daniele Parenti^b ; ^c ; ¹ ; Alessia Grozio^a ; Inga Bauer^b ; Mario Passalacqua^a ; Silvia Boero^b ; ^d ; Alessandra Donadini^b ; Enrico Millo^a ; Marta Bellotti^a ; Laura Sturla^a ; Patrizia Damonte^b ; Alessandra Puddu^b ; Claudia Ferroni^e ; Greta Varchi^e ; Claudio Franceschi^c ; ^e ; Alberto Ballestrero^b ; ^d ; Alessandro Poggi^d ; Santina Bruzzone^a ; ^{santina.bruzzone@unige.it" class="auth_mail" title="E-mail the corresponding author} ; Alessio Nencioni^b ; ^d ; ^{alessio.nencioni@unige.it" class="auth_mail" title="E-mail the corresponding author} ; Alberto Del Rio^c ; ^e ; ^{alberto.delrio@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Sirtuins ; Small molecule inhibitors ; Anticancer drugs ; Chemotherapy ; Quinazolinedione ; Molecular design ; NAD+-dependent deacetylases

刊名：European Journal of Medicinal Chemistry

出版年：2015

3.Design and discovery of novel quinazolinedione-based redox modulators as therapies for pancreatic cancer

作者：Divya Pathania ; Mario Sechi ; Michele Palomba ; Vanna Sanna ; Francesco Berrettini ; Angela Sias ; Laleh Taheri ; Nouri Neamati

关键词：CMFDA ; 5-chloromethylfluorescein diacetate ; DMEM ; Dulbecco's Modified Eagle Medium ; DMSO ; dimethyl sulfoxide ; DNA ; deoxyribonucleic acid ; DPBS ; Dulbecco's Phosphate Buffered Saline ; DRAQ5® ; 1 ; 5-bis{[2-(di-methylamino) ethyl]amino}-4 ; 8-dihydroxyanthracene-9 ; 10-dione ; EDTA ; ethylene diaminetetraacetic acid ; FoxO3a ; forkhead box transcription factor 3a ; GAPDH ; glyceraldehyde 3-phosphate dehydrogenase ; GSH ; glutathione (reduced) ; JNK ; c-Jun N-terminal kinase ; MnSOD ; manganese superoxide dismutas

刊名：Biochimica et Biophysica Acta (BBA)/General Subjects

出版年：January, 2014

4.A facile and convenient approach for the one-pot synthesis of 2,4(1H,3H)-quinazolinediones

作者：Mahnaz Sharafi-Kolkeshvandi ; Farzad Nikpour ; ^{fnikpour@uok.ac.ir}

关键词：Anthranilic acid ; Potassium cyanate ; Quinazolinediones ; Benzoylenurea ; Cyclization reaction

刊名：Chinese Chemical Letters

出版年：2012

5.Construction of functionalized tricyclic dihydropyrazino-quinazolinedione chemotypes via an Ugi/N-acyliminium ion cyclization cascade

作者：Steven Gunawan ; Christopher Hulme

关键词：Peptidomimetics ; Ugi reaction ; Multi-component reaction ; N-acyliminium ion ; Heterocycles

刊名：Tetrahedron Letters

出版年：2013

6.Sensing of Hg⁺² and Ag⁺ through a pH dependent FRET system: Fabrication of molecular logic gates

作者：Partha Bairi ; Priyadarshi Chakraborty ; Bappaditya Roy ; Arun K. Ni

关键词：FRET ; Sensor ; Lumichrome ; Logic gates ; Nanoparticles ; Quenching

刊名：Sensors and Actuators B: Chemical

出版年：31 March, 2014

7.6-Amino quinazolinedione sulfonamides as orally active competitive AMPA receptor antagonists

作者：David Orain^a ; ^{david.orain@novartis.com} ; Silvio Ofner^a ; Manuel Koller^a ; David A. Carcache^a ; Wolfgang Froestl^a ; Hans Allgeier^a ; Vittorio Rasetti^a ; Joachim Nozulak^a ; Henri Mattes^a ; Nicolas Soldermann^a ; Philipp Floersheim^a ; Sandrine Desrayaud^a ; Joerg Kallen^b ; Kurt Lingenhoehl^c ; Stephan Urwyler^d ; ^&dagger ;

关键词：AMPA receptor antagonist ; Quinazoline-2 ; 4-dione sulfonamide ; Glutamate receptors ; Anticonvulsant ; Orally active

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2012

8.Peripheral and spinal 5-HT receptors participate in the pronociceptive and antinociceptive effects of fluoxetine in rats

作者：C. Cervantes-Dur¨¢n ; H.I. Rocha-Gonz¨¢lez ; V. Granados-Soto

关键词：ANOVA ; one-way analysis of variance ; AUC ; area under the number of flinches against time curves ; 5-HT ; 5-hydroxytryptamine ; BRL-15572 ; 4-(3-chlorophenyl)-¦Á-(diphenylmethyl)-1-piperazineethanol hydrochloride ; DRG ; dorsal root ganglion ; GR-113808 ; [1-[2-me

刊名：Neuroscience

出版年：2013

9.Quinazolinedione sulfonamides: A novel class of competitive AMPA receptor antagonists with oral activity

作者：Manuel Koller^a ; ^{manuel.koller@novartis.com"" rel=""nofollow} ; Kurt Lingenhoehl^b ; Markus Schmutz^b ; Ivan-Toma Vranesic^c ; Joerg Kallen^d ; Yves P. Auberson^a ; David A. Carcache^a ; Henri Mattes^a ; Silvio Ofner^a ; David Orain^a ; Stephan Urwyler^e

关键词：AMPA receptor antagonists ; Anticonvulsants ; Excitatory amino acids ; Glutamate receptors ; Quinazoline-2 ; 4-dione sulfonamides

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2011

10.The simple synthesis of quinazoline-2,4-dione derivatives using Boc strategy

作者：Xu Qin Li

关键词：Quinazolinediones ; Carbonylation ; Cyclization ; Boc strategy

刊名：Chinese Chemical Letters

出版年：2009

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