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Elsevier电子期刊(15)

在“Elsevier电子期刊”中，命中：15条，耗时：小于0.01 秒

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1.Development and validation of an enantioselective SFC-MS/MS method for simultaneous separation and quantification of oxcarbazepine and its chiral metabolites in beagle dog plasma

作者：Zhichao Yang^a ; Xueyu Xu^a ; Lingxia Sun^a ; Xue Zhao^a ; Hao Wang^a ; John Paul Fawcett^b ; Yan Yang^a ; ^{yyan@jlu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Jingkai Gu^c ; ^{gujk@jlu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：SFC-MS/MS ; UPC2 ; Oxcarbazepine ; Chiral analysis ; S-Licarbazepine ; R-Licarbazepine

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

2.A new PAMPA model using an in-house brain lipid extract for screening the blood-brain barrier permeability of drug candidates

作者：Joana Bicker^a ; ^b ; Gilberto Alves^b ; ^c ; Ana Fortuna^a ; ^b ; Patrí ; cio Soares-da-Silva^d ; ^e ; Amí ; lcar Falcã ; o^a ; ^b ; ^{acfalcao@ff.uc.pt" class="auth_mail" title="E-mail the corresponding author} ; ^{acfalcao@uc.pt" class="auth_mail" title="E-mail the corresponding author}

关键词：Entacapone (PubChem CID ; 5281081) ; Eslicarbazepine acetate (PubChem CID ; 179344) ; Etamicastat (PubChem CID ; 10450387) ; S-licarbazepine (PubChem CID ; 114709) ; Nebicapone (PubChem CID ; 9838389) ; Nepicastat hydrochloride (PubChem CID ; 9840545) ; Opicapone (PubChem CID ; 76966913) ; Tolcapone (PubChem CID ; 4659569) ; Zamicastat (PubChem CID ; 25156755)

刊名：International Journal of Pharmaceutics

出版年：2016

3.Effect of eslicarbazepine acetate in the corneal kindling progression and the amygdala kindling model of temporal lobe epilepsy

作者：Heidrun Potschka ; Jonna Soerensen ; Anton Pekcec ; Ana Loureiro ; Patr铆cio Soares-da-Silva

关键词：Anticonvulsant drugs ; Eslicarbazepine acetate ; Eslicarbazepine ; (R)-licarbazepine ; Corneal kindling ; Amygdala kindling

刊名：Epilepsy Research

出版年：February, 2014

4.Synthesis of S-licarbazepine by asymmetric reduction of oxcarbazepine with Saccharomyces cerevisiae CGMCC No. 2266

作者：Zhi-Min ; Ou^a ; ; ^{oozzmm@163.com} ; Han-Bing ; Shi^b ; Xing-Yuan ; Sun^b ; Wen-He ; Shen^c

关键词：S-licarbazepine ; Asymmetric reduction ; Oxcarbazepine ; Biotransformation

刊名：Journal of Molecular Catalysis B: Enzymatic

出版年：2011

5.First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plas

作者：Ana Serralheiro^a ; ^b ; Gilberto Alves^b ; ^c ; ^{gilberto@fcsaude.ubi.pt} ; Ana Fortuna^a ; ^b ; Marí ; lia Rocha^b ; ^d ; Amí ; lcar Falcã ; o^a ; ^b

关键词：Antiepileptic drugs ; High-performance liquid chromatography ; Human plasma ; Bioanalytical method validation ; Therapeutic drug monitoring

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2013

6.Development and validation of an enantioselective liquid-chromatography/tandem mass spectrometry method for the separation and quantification of eslicarbazepine acetate, eslicarbazepine, R-licarbazepine and oxcarbazepine in human plasma

作者：A.I. Loureiro^a ; C. Fernandes-Lopes^a ; L.C. Wright^a ; P. Soares-da-Silva^a ; ^b ; ^{psoares.silva@bial.com} ; ^{pss@med.up.pt}

关键词：Eslicarbazepine acetate ; Eslicarbazepine ; R-licarbazepine ; Oxcarbazepine ; Antiepileptic drugs ; LC&ndash ; MS/MS

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2011

7.Evaluation of neurotoxic and neuroprotective pathways affected by antiepileptic drugs in cultured hippocampal neurons

作者：Maria I. Morte ; Bruno P. Carreira ; Maria J. Falc茫o ; Ant贸nio F. Ambr贸sio ; Patr铆cio Soares-da-Silva ; In锚s M. Ara煤jo ; Caetana M. Carvalho

关键词：AEDs ; antiepileptic drugs ; AIF ; apoptosis-inducing factor ; BCA ; bicinchoninic acid ; BSA ; bovine serum albumin ; CBZ ; carbamazepine ; CNS ; central nervous system ; DTT ; dithiothreitol ; ESL ; eslicarbazepine acetate ; S-Lic ; S-licarbazepine ; ERK ; extracellular signal-regulated kinase ; GABA ; gamma-aminobutyric acid ; LTG ; lamotrigine ; MAPK ; mitogen-activated protein kinase ; OXC ; oxcarbazepine ; PARP ; poly-ADP ribose polymerase ; PBS ; phosphate-buffered saline ; PMSF ; phenylmethylsulphonyl fluoride ; R-Lic ; R

刊名：Toxicology in Vitro

出版年：December, 2013

8.Pharmacokinetics, brain distribution and plasma protein binding of carbamazepine and nine derivatives: New set of data for predictive in silico ADME models

作者：Ana Fortuna ; Gilberto Alves ; Patr铆cio Soares-da-Silva ; Am铆lcar Falc茫o

关键词：ADME ; absorption distribution metabolism and excretion ; AEDs ; antiepileptic drugs ; AUC ; area under the plasma drug concentration&ndash ; time curve ; BBB ; blood&ndash ; brain barrier ; CBZ ; carbamazepine ; CBZ-E ; carbamazepine-10 ; 11-epoxide ; Cmax ; maximum peak concentration ; CNS ; central nervous system ; DMSO ; dimethyl sulfoxide ; ED50 ; effective dose for protecting at 50% ; ESL ; eslicarbazepine acetate ; HPLC ; high performance liquid chromatography ; IS ; internal standard ; LOQ ; limit of quantification ; MES

刊名：Epilepsy Research

出版年：November, 2013

9.Development of liquid chromatographic enantiomer separation methods and validation for the estimation of (R)-enantiomer in eslicarbazepine acetate

作者：Mahesh Kumar Mone ; K.B. Ch ; rasekhar

关键词：Eslicarbazepine acetate ; Licarbazepine ; Enantiomeric separation ; Chiral stationary phase ; Polar organic solvent chromatography

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2011

10.Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection

作者：Gilberto Alves ; Isabel Figueiredo ; Margarida Castel-Branco ; Ana Loureiro ; Amí ; lcar Falcã ; o ; Margarida Caramona

关键词：Eslicarbazepine acetate ; Oxcarbazepine ; Mouse tissue samples ; Enantioselective liquid chromatography ; Bioanalytical method validation

刊名：Analytica Chimica Acta

出版年：2007

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