搜索页_+Radioligand+binding+assays

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在“Elsevier电子期刊”中，命中：555条，耗时：0.0319848 秒

在所有数据库中总计命中：736条

1.Cocaine self-administration, extinction training and drug-induced relapse change metabotropic glutamate mGlu5 receptors expression: Evidence from radioligand binding and immunohistochemistry assays

作者：Lucyna Pomierny-Chamiolo^a ; ^{lpomiern@cm-uj.krakow.pl} ; Joanna Miszkiel^b ; Malgorzata Frankowska^b ; Beata Bystrowska^a ; Malgorzata Filip^b

关键词：Cocaine self-administration ; Extinction training ; Drug-induced relapse ; MGlu5 receptor binding ; MGlu5 receptor immunohistochemistry

刊名：Brain Research

出版年：2017

2.Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand binding studies

作者：Aliaa Abdelrahman^a ; Vigneshwaran Namasivayam^a ; ^c ; Sonja Hinz^a ; Anke C. Schiedel^a ; Meryem Kö ; se^a ; Maggi Burton^b ; Ali El-Tayeb^a ; ¹ ; Michel Gillard^b ; Jü ; rgen Bajorath^c ; Marc de Ryck^b ; Christa E. Mü ; ller^a ; ^{christa.mueller@uni-bonn.de}

关键词：Ap3A ; diadenosine triphosphate ; Ap4A ; diadenosine tetraphosphate ; Ap5A ; diadenosine pentaphosphate ; AR-C67085MX ; 2-propylthio-β ; γ-dichloromethylene-ATP ; PSB0412 ; 2-propargylthio-β ; γ-dichloromethylene-ATP ; 5-BDBD ; 5-(3-bromophenyl)-1 ; 3-dihydro-2H-benzofuro[3 ; 2-e]-1 ; 4-diazepin-2-one ; BzATP ; 2&prime ; (3&prime ; )-O-(4-benzoylbenzoyl)adenosine 5&prime ; -triphosphate ; CHO-K1 cells ; Chinese hamster ovary cells ; HBSS ; Hank&rsquo ; s balanced salt solution ; HEPES ; 4-(2-hydroxyethyl)-1-piperazine ethanesulfoni

刊名：Biochemical Pharmacology

出版年：2017

3.High affinity binding of the peptide agonist TIP-39 to the parathyroid hormone 2 (PTH₂) receptor requires the hydroxyl group of Tyr-318 on transmembrane helix 5

作者：Richard E. Weaver^a ; Juan C. Mobarec^c ; Mark J. Wigglesworth^b ; ¹ ; Christopher A. Reynolds^c ; Dan Donnelly^a ; ^{d.donnelly@leeds.ac.uk}

关键词：Parathyroid hormone ; PTH ; GPCR ; Agonist ; Receptor ; TIP39

刊名：Biochemical Pharmacology

出版年：2017

4.Characterization of monoacylglycerol acyltransferase 2 inhibitors by a novel probe in binding assays

作者：Zhengping Ma^a ; Hannguang J. Chao^b ; Huji Turdi^b ; Jon J. Hangeland^b ; Todd Friends^b ; Lisa M. Kopcho^c ; R. Michael Lawrence^b ; Dong Cheng^a ; ^{dong.cheng@bms.com" class="auth_mail" title="E-mail the corresponding author}

关键词：MGAT2 ; Enzyme inhibitor binding assay ; Enzyme inhibitor kinetics ; Acyltransferase ; Triglyceride synthesis

刊名：Analytical Biochemistry

出版年：2016

5.Homogeneous time-resolved G protein-coupled receptor-ligand binding assay based on fluorescence cross-correlation spectroscopy

作者：Thomas Antoine^a ; ¹ ; David Ott^a ; ¹ ; Katharina Ebell^a ; Kerrin Hansen^a ; Luc Henry^b ; Frank Becker^a ; Stefan Hannus^a ; ^{stefan.hannus@intana.de" class="auth_mail" title="E-mail the corresponding author}

关键词：GPCR ; Homogeneous time-resolved binding assay ; Fluorescence correlation spectroscopy ; Fluorescence cross-correlation spectroscopy ; Affinity determination ; Binding kinetics

刊名：Analytical Biochemistry

出版年：2016

6.An LP1 analogue, selective MOR agonist with a peculiar pharmacological profile, used to scrutiny the ligand binding domain

作者：Simone Ronsisvalle^a ; ^{s.ronsisvalle@unict.it" class="auth_mail" title="E-mail the corresponding author} ; Giuseppina Aricò ; ^a ; Federica Panarello^a ; Angelo Spadaro^a ; Lorella Pasquinucci^a ; Maria S. Pappalardo^a ; Carmela Parenti^b ; Nicole Ronsisvalle^c

关键词：MOR agonists ; 6 ; 7-Benzomorphan scaffold ; Modeling studies ; Radioligand competition-binding assay ; Tail-flick test ; GPI and MVD assays

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

7.Label-free versus conventional cellular assays: Functional investigations on the human histamine H₁ receptor

作者：S. Lieb^a ; ¹ ; T. Littmann^a ; ¹ ; N. Plank^a ; ¹ ; J. Felixberger^a ; M. Tanaka^b ; T. Schä ; fer^c ; S. Krief^d ; S. Elz^a ; K. Friedland^c ; G. Bernhardt^a ; J. Wegener^e ; T. Ozawa^b ; A. Buschauer^a ; ^{Armin.Buschauer@ur.de}

关键词：Histamine dihydrochloride (PubChem CID ; 5818) ; Betahistine dihydrochloride (CID ; 68643) ; Diphenhydramine hydrochloride (PubChem CID ; 8980) ; Cyproheptadine hydrochloride (PubChem CID ; 13770) ; Maprotiline hydrochloride (PubChem CID ; 71478) ; Fexofenadine hydrochloride (PubChem CID ; 63002) ; FR900359 (PubChem CID ; 14101198) ; Mepyramine maleate (PubChem CID ; 5284451) ; [3H]mepyramine (PubChem CID ; 656400) ; 2-(3-Trifluoromethylphenyl)histamine (PubChem CID ; 5310982) ; Histaprodifen (PubChem CID ; 10447834

刊名：Pharmacological Research

出版年：2016

8.Evaluation of N-substituent structural variations in opioid receptor profile of LP1

作者：Lorella Pasquinucci^a ; Rita Turnaturi^a ; ^{rita.turnaturi@tiscali.it" class="auth_mail" title="E-mail the corresponding author} ; Giuseppina Aricò ; ^a ; Carmela Parenti^b ; Paschalina Pallaki^c ; Zafiroula Georgoussi^c ; Simone Ronsisvalle^a

关键词：Mu opioid receptor ; 6 ; 7-Benzomorhan scaffold ; Radioligand competition-binding assay ; GPI and MVD assays ; Tail-flick test ; Modeling studies

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

9.Brain penetrant small molecule ¹⁸F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats

作者：Dag E. Olberg^a ; ^b ; ^{dag.erlend.olberg@petsenteret.no" class="auth_mail" title="E-mail the corresponding author} ; Nadine Bauer^c ; Kjetil W. Andressen^d ; ^e ; Trine Hjø ; rnevik^f ; Paul Cumming^g ; ^h ; Finn O. Levy^d ; ^e ; Jo Klaveness^b ; Ira Haraldsen^g ; Julie L. Sutcliffe^c ; ⁱ ; ^j ; ^k

关键词：PET ; Positron emission tomography ; GPCR ; G-protein coupled receptor ; GnRH-R ; gonadotropin releasing hormone receptor

刊名：Nuclear Medicine and Biology

出版年：2016

10.Characterization of PCS1055, a novel muscarinic M₄ receptor antagonist

作者：Carrie H. Croy^b ; Wai Y. Chan^a ; ¹ ; Andrea M. Castetter^b ; Marla L. Watt^b ; ² ; Anne T. Quets^b ; Christian C. Felder^b ; ^{Felder@lilly.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Muscarinic M4 receptors ; Competitive antagonists ; PCS1055 ; Subtype selectivity

刊名：European Journal of Pharmacology

出版年：2016

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