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在“Elsevier电子期刊”中，命中：18,987条，耗时：0.072966 秒

在所有数据库中总计命中：22,865条

1.An evaluation of central penetration from a peripherally administered oxytocin receptor selective antagonist in nonhuman primates

作者：Aaron L. Smith^a ; ^b ; ^c ; ^{asmit53@emory.edu} ; Hasse Walum^a ; Fawn Connor-Stroud^d ; Sara M. Freeman^e ; Kiyoshi Inoue^a ; Lisa A. Parr^a ; Mark M. Goodman^a ; ^b ; ^c ; Larry J. Young^a

关键词：Oxytocin antagonist ; Oxytocin receptor ; PET imaging ; Rhesus macaque ; Cerebrospinal fluid

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.Modulation of RAAS-natriuretic peptides in the treatment of HF: Old guys and newcomers

作者：Vincenzo Mollace^a ; Micaela Gliozzi^a ; ^{micaela.gliozzi@gmail.com} ; Annalisa Capuano^b ; Francesco Rossi^b

关键词：Renin&ndash ; angiotensin&ndash ; aldosterone system ; Heart failure ; RAAS inhibitors ; AT1-receptor modulators ; AT2-receptor modulators

刊名：International Journal of Cardiology

出版年：2017

3.Cardiovascular remodeling and the peripheral serotonergic system

作者：Estelle Ayme-Dietrich^a ; Gaë ; lle Aubertin-Kirch^a ; Luc Maroteaux^b ; Laurent Monassier^a ; ^{laurent.monassier@unistra.fr}

关键词：Serotonin ; Cardiac remodeling ; Cardiac hypertrophy ; Valve degeneration ; Fibrosis

刊名：Archives of Cardiovascular Diseases

出版年：2017

4.Monoclonal antibody therapy for the treatment of asthma and chronic obstructive pulmonary disease with eosinophilic inflammation

作者：John Nixon^a ; Paul Newbold^b ; Tomas Mustelin^b ; Gary P. Anderson^c ; Roland Kolbeck^b ; ^{KolbeckR@medimmune.com}

刊名：Pharmacology & Therapeutics

出版年：2017

5.Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology

作者：Craig A. Stump^a ; ; Andrew J. Cooke^a ; Joseph Bruno^d ; Tamara D. Cabalu^c ; Anthony L. Gotter^b ; C. Meacham Harell^b ; Scott D. Kuduk^a ; Terrence P. McDonald^b ; Julie O&rsquo ; Brien^d ; John J. Renger^b ; Peter D. Williams^a ; Christopher J. Winrow^b ; Paul J. Coleman^a

关键词：Selective orexin receptor antagonist (SORA) ; Dual orexin receptor antagonist (DORA) ; Orexin-1 ; Suvorexant ; Filorexant

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

6.Bitter taste receptors: Novel insights into the biochemistry and pharmacology

作者：Appalaraju Jaggupilli^a ; ^b ; Ryan Howard^a ; Jasbir D. Upadhyaya^a ; ^b ; Rajinder P. Bhullar^a ; Prashen Chelikani^a ; ^b ; ^c ; ^{Prashen.Chelikani@umanitoba.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：GPCRs ; G protein-coupled receptors ; T2Rs ; bitter taste receptors ; CAMs ; constitutive active mutants ; TM ; transmembrane ; PLCβ2 ; phospholipase Cβ2 ; IP3 ; inositol-14 ; 5-triphosphate ; ECL ; extracellular loop ; ICL ; intracellular loop

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

7.Synoptic pharmacology: Detecting and assessing the pharmacological significance of ligands for orphan receptors

作者：Terry P. Kenakin ; ^{kenakin@email.unc.edu}

关键词：Receptors ; GPCRs ; Orphan receptors ; Screening ; Constitutive ; activity

刊名：Pharmacological Research

出版年：2016

8.Pharmacology of dextromethorphan: Relevance to dextromethorphan/quinidine (Nuedexta®) clinical use

作者：Charles P. Taylor^a ; ^{taylor.charles54@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Stephen F. Traynelis^b ; Joao Siffert^c ; Laura E. Pope^c ; Rae R. Matsumoto^d

关键词：NMDA receptors ; Pseudobulbar affect ; Serotonin transporter ; Nicotinic receptor ; Sigma receptor ; Pharmacokinetics

刊名：Pharmacology and Therapeutics

出版年：2016

9.High and low GABA sensitivity α4β2δ GABA_A receptors are expressed in Xenopus laevis oocytes with divergent stoichiometries

作者：Leonny Y. Hartiadi ; Philip K. Ahring ; Mary Chebib¹ ; Nathan L. Absalom ; ¹ ; ^{nathan.absalom@sydney.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：GABAA receptor ; γ-amino butyric acid receptor type A ; DS ; Delta Selective ; THIP ; tetrahydroisoxazolopyridinol ; CRR ; concentration&ndash ; response relationship

刊名：Biochemical Pharmacology

出版年：2016

10.Unravelling intrinsic efficacy and ligand bias at G protein coupled receptors: A practical guide to assessing functional data

作者：Lisa A. Stott^a ; David A. Hall^b ; Nicholas D. Holliday^a ; ^{nicholas.holliday@nottingham.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：CRC ; concentration response curve ; EC50 ; effective agonist concentration for 50% maximum response ; Emax ; maximum system response ; GPCR ; G protein coupled receptor ; D2R ; dopamine D2 receptor ; GTPγS ; guanosine 5&prime ; -O-[γ-thio]triphosphate ; KA ; agonist equilibrium dissociation constant ; KE ; concentration of agonist&ndash ; receptor complex which produces a half maximal effect ; MAPK ; mitogen activated protein kinase ; RAi ; relative intrinsic activity ratio ; Rmax ; maximum agonist response ; RT ; total

刊名：Biochemical Pharmacology

出版年：2016

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