搜索页_+Reverse-transcriptase+inhibitors

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在“Elsevier电子期刊”中，命中：1,448条，耗时：0.0279867 秒

在所有数据库中总计命中：2,159条

1.Mitochondrial defects arise from nucleoside/nucleotide reverse transcriptase inhibitors in neurons: Potential contribution to HIV-associated neurocognitive disorders

作者：Kui-Ming Hung^a ; ^b ; Pei-Chun Chen^b ; Han-Chieh Hsieh^c ; Marcus J Calkins^a ; ^{mjcalkins@mail.ncku.edu.tw}

关键词：NRTI ; nucleoside/nucleotide reverse transcriptase inhibitor ; HAND ; HIV-associated neurocognitive disorders ; cART ; combination antiretroviral therapy ; pol γ ; polymerase γ ; mtDNA ; mitochondrial DNA ; ddI ; didanosine ; AZT ; zidovudine ; FTC ; emtricitabine ; TDF ; tenofovir ; ddC ; zalcitabine ; d4T ; stavudine ; 3TC ; lamivudine ; ABC ; abacavir ; PGC-1α ; peroxisome proliferator-activated receptor γ coactivator 1α ; mtUPR ; mitochondrial unfolded protein response ; CO1 ; Cytochrome oxidase I ; ND1 ; NADH Dehydrogenase

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

2.Body composition and metabolic outcomes after 96 weeks of treatment with ritonavir-boosted lopinavir plus either nucleoside or nucleotide reverse transcriptase inhibitors or raltegravir in patients with HIV with virological failure of a standard first-line antiretroviral therapy regimen: a substudy of the randomised, open-label, non-inferiority SEC

作者：Prof Mark A Boyd ; MD^a ; ^b ; ^{mark.boyd@adelaide.edu.au} ; Janaki Amin ; PhD^b ; Patrick W G Mallon ; PhD^c ; Nagalingeswaran Kumarasamy ; MD^d ; Johan Lombaard ; MD^e ; Prof Robin Wood ; PhD^f ; Prof Ploenchan Chetchotisakd ; MD^g ; Prof Praphan Phanuphak ; PhD^h ; Lerato Mohapi ; MDⁱ ; Iskandar Azwa ; MD^j ; Waldo H Belloso ; MD^k ; Prof Jean-Michel Molina ; PhD^l ; Prof Jennifer Hoy ; MD^m ; Cecilia L Moore ; MIPH^b ; Prof Sean Emery ; PhD^b ; Prof David A Cooper ; FAA^b ; on behalf of the SECOND-LINE Study Group^&dagger ;

刊名：The Lancet HIV

出版年：2017

3.Efavirenz dissolution enhancement III: Colloid milling, pharmacokinetics and electronic tongue evaluation

作者：Cristiane R.D. Hoffmeister^a ; Cinira Fandaruff^b ; Maí ; ra A. da Costa^a ; Lucio M. Cabral^c ; Luciana R. Pitta^d ; Stanley E.R. Bilatto^e ; ^f ; Livia D. Prado^a ; Daniel S. Corrê ; a^e ; ^f ; Leandro Tasso^g ; Marcos Antô ; nio S. Silva^b ; Helvé ; cio V.A. Rocha^a ; ^c ; ^{helveciorocha@far.fiocruz.br}

关键词：EFV ; efavirenz ; NNRTI ; non-nucleoside reverse transcriptase inhibitor ; HIV-1/AIDS ; human immunodeficiency virus type 1 infection ; SLS ; sodium lauryl sulfate ; HPC ; hydroxypropylcellulose ; HPMC ; hydroxypropylmetilcellulose ; NRTIs ; nucleoside reverse transcriptase inhibitors ; API ; active pharmaceutical ingredient ; CD ; cyclodextrin ; FDA ; Food and Drug Administration ; AUC ; area under the curve

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

4.Catalytic synthesis of α-amino chromone phosphonates and their antimicrobial, toxicity and potential HIV-1 RT inhibitors based on silico screening

作者：Abosede Oluwabukola Jaiyeola^a ; K. Anand^a ; ^b ; ^{organicanand@gmail.com} ; K. Kasumbwe^c ; M. Ramesh^d ; R.M. Gengan^a ; ^{genganrm@dut.ac.za}

关键词：Boron nitride ; Kabachnik-Fields reaction ; Molecular docking ; Antimicrobial ; HIV-1 reverse transcriptase

刊名：Journal of Photochemistry and Photobiology B: Biology

出版年：2017

5.Design, synthesis and anti-HIV-1 RT evaluation of 2-(benzyl(4-chlorophenyl)amino)-1-(piperazin-1-yl)ethanone derivatives

作者：Subhash Chander^a ; Ping Wang^b ; Penta Ashok^a ; Liu-Meng Yang^b ; Yong-Tang Zheng^b ; ^{zhengyt@mail.kiz.ac.cn} ; Murugesan Sankaranarayanan^a ; ^{murugesan@pilani.bits-pilani.ac.in}

关键词：Enzymatic assay ; Wild strain ; Reverse transcriptase ; Docking ; Cytotoxicity

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

6.Identifications of drug resistance mutations among antiretroviral treatment naive HIV-1 patients in Peninsular Malaysia

作者：Rozainanee Mohd Zain ; ^{rozainanee@yahoo.com} ; Nabila Ibrahim ; Suriani Ismail ; Jeyanthi Suppiah ; Nor Aziyah Mat Rahim ; Ravindran Thayan

关键词：HIV ; Resistance ; Malaysia ; Antiretroviral treatment naive

刊名：Asian Pacific Journal of Tropical Medicine

出版年：2017

7.Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy

作者：Ayako Hoshi^a ; Takeshi Sakamoto^a ; ^{sakamoto@josai.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Jun Takayama^a ; Meiyan Xuan^a ; Mari Okazaki^a ; Tracy L. Hartman^b ; Robert W. Buckheit Jr.^b ; Christophe Pannecouque^c ; Mark Cushman^d ; ^{cushman@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ADAM ; alkenyldiarylmethane ; NNRTI ; non-nucleoside reverse transcriptase inhibitor ; RT ; reverse transcriptase ; HIV-1 ; human immunodeficiency virus type 1 ; AIDS ; acquired immune deficiency syndrome ; ART ; antiretroviral therapy ; NRTI ; nucleoside reverse transcriptase inhibitor ; PI ; protease inhibitor ; INI ; integrase inhibitors ; FI ; fusion inhibitor ; CCR5I ; CC chemokine receptor inhibitor ; dNTPs ; deoxynucleoside triphosphate ; AZT ; azidothymidine (zidovudine) ; EDCI ; 1-(3-dimethylaminopropyl)-3-ethylc

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

8.Advances in rationally designed dual inhibitors of HIV-1 reverse transcriptase and integrase

作者：Shuang-Xi Gu^a ; ^{shuangxigu@163.com" class="auth_mail" title="E-mail the corresponding author} ; Ping Xue^a ; Xiu-Lian Ju^a ; Yuan-Yuan Zhu^b ; ^{yyzhu531@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：HIV ; AIDS ; Reverse transcriptase ; Integrase ; Rational drug design ; Dual inhibitors

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

9.Hydrophobic-core PEGylated graft copolymer-stabilized nanoparticles composed of insoluble non-nucleoside reverse transcriptase inhibitors exhibit strong anti-HIV activity

作者：Anita Leporati^a ; Mikhail S. Novikov^b ; Vladimir T. Valuev-Elliston^c ; Sergey P. Korolev^d ; Anastasia L. Khandazhinskaya^c ; Sergey N. Kochetkov^c ; Suresh Gupta^a ; Julian Goding^a ; Elijah Bolotin^e ; Marina B. Gottikh^d ; Alexei A. Bogdanov Jr.^a ; ^{Alexei.Bogdanov@umassmed.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Non-nucleoside reverse transcriptase inhibitors ; Microbicide ; HIV-1 ; Nanoparticle ; Copolymer ; Benzophenone-uracyl

刊名：Nanomedicine: Nanotechnology, Biology and Medicine

出版年：2016

10.An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1 reverse transcriptase mutations versus Indole Aryl Sulphones

作者：Alberto Massarotti^a ; ¹ ; Antonio Coluccia^b ; ¹ ; ^{antonio.coluccia@uniroma1.it" class="auth_mail" title="E-mail the corresponding author}

关键词：Non nucleoside reverse transcriptase inhibitors ; Drug resistant reverse transcriptase ; Molecular dynamics

刊名：Journal of Molecular Graphics and Modelling

出版年：2016

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