搜索页_+Sodium-dependent+glucose+cotransporter+2

设为首页

收藏本站

网站地图 | English | 公务邮箱

远程访问

NSTL服务站

外文资源

Elsevier电子期刊(39)

在“Elsevier电子期刊”中，命中：39条，耗时：0.0639756 秒

在所有数据库中总计命中：71条

1.Effect of ipragliflozin, an SGLT2 inhibitor, on progression of diabetic microvascular complications in spontaneously diabetic Torii fatty rats

作者：Shoji Takakura^a ; ^{shoji.takakura@astellas.com" class="auth_mail" title="E-mail the corresponding author} ; Tohru Toyoshi^b ; Yuka Hayashizaki^a ; Toshiyuki Takasu^a

关键词：Type 2 diabetes mellitus ; Diabetic microvascular complications ; Retinopathy ; Nephropathy ; Neuropathy ; Cataract ; Sodium-dependent glucose cotransporter 2 ; Ipragliflozin L-proline (PubChem CID ; 57339444)

刊名：Life Sciences

出版年：2016

2.Single-dose Pharmacokinetics and Pharmacodynamics of Canagliflozin, a Selective Inhibitor of Sodium Glucose Cotransporter 2, in Healthy Indian Participants

作者：Damayanthi Devineni ; PhD¹ ; ^{ddevinen@its.jnj.com" class="auth_mail" title="E-mail the corresponding author} ; David Polidori ; PhD² ; Christopher Curtin ; BSc¹ ; Hans Stieltjes ; MSc³ ; Hong Tian ; PhD¹ ; Ewa Wajs ; MD ; PhD³

关键词：canagliflozin ; India ; pharmacodynamics ; pharmacokinetics ; safety

刊名：Clinical Therapeutics

出版年：2016

3.Sodium glucose CoTransporter 2 (SGLT2) inhibitors: Current status and future perspective

作者：Tushar Madaan ; Mohd. Akhtar ; Abul Kalam Najmi ; ^{aknajmi@jamiahamdard.ac.in" class="auth_mail" title="E-mail the corresponding author} ; ^{aknajmi@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Dapagliflozin (Pubchem CID ; 9887712) ; Canagliflozin (Pubchem CID ; 24812758) ; Empagliflozin (Pubchem CID ; 11949646) ; Ipragliflozin (Pubchem CID ; 10453870) ; Tofogliflozin (Pubchem CID ; 46908929) ; Luseogliflozin (Pubchem CID ; 11988953) ; Remogliflozin etabonate (Pubchem CID ; 9871420)

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

4.Predicting the biological activities of triazole derivatives as SGLT2 inhibitors using multilayer perceptron neural network, support vector machine, and projection pursuit regression models

作者：Jintao Yuan^a ; ^c ; Shuling Yu^b ; ^{yushuling@henu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Shufang Gao^b ; Ying Gan^b ; Yi Zhang^b ; Ting Zhang^c ; Yali Wang^b ; Liu Yang^b ; ^d ; Jiahua Shi^b ; ^{sjiahua@henu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Wu Yao^a ; ^{yaowu@zzu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Quantitative structure&ndash ; activity relationship ; Sodium-dependent glucose cotransporters-2 ; Multilayer perceptron neural network ; Support vector machine ; Projection pursuit regression

刊名：Chemometrics and Intelligent Laboratory Systems

出版年：2016

5.Bioequivalence and food effect of heat-stressed and non⿿heat-stressed dapagliflozin 2.5- and 10-mg tablets

关键词：AUC0⿿t ; area under the plasma concentration⿿time curve from time 0 to the last quantifiable concentration ; AUC0⿿inf ; area under the plasma concentration⿿time curve from time 0 to infinity ; Cp ; plasma concentration ; Cmax ; maximum Cp ; Dapagliflozin ; [2S ; 3R ; 4R ; 5S ; 6R]-2-[4-chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-34 ; 5-triol ; compounded with (2S)-1 ; 2-propanediol ; hydrate (11 ; 1) ; HS ; heat-stressed ; Kel ; terminal rate constant ; LS ; least squares ; NH ; non⿿heat-stressed ; tm

刊名：International Journal of Pharmaceutics

出版年：2016

6.Antidiabetic potential of a novel dual-target activator of glucokinase and peroxisome proliferator activated receptor-纬

作者：Lei Lei ; Quan Liu ; Shuainan Liu ; Yi Huan ; Sujuan Sun ; Zhiyu Chen ; Linyi Li ; Zhiqiang Feng ; Yan Li ; Zhufang Shen ; ^{shenzhf@imm.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：GK ; glucokinase ; PPAR纬 ; peroxisome proliferator activated receptor-纬 ; GLP-1 ; glucogan-like peptide-1 ; DPP-4 ; dipeptidyl peptidase-4 ; SGLT2 ; sodium-dependent glucose cotransporter-2 ; TAC ; tricarboxylic acid cycle ; RXR ; heterodimers with retinal X receptor ; PPRE ; PPAR response element ; G6PDH ; glucose-6-phosphate dehydrate ; TG ; triglyceride ; FFA ; free fatty acid ; CHO ; cholesterol ; SOD ; superoxide dismutase ; MDA ; malondialdehyde ; DMEM ; Dulbecco&rsquo ; s Modified Eagle Medium ; OGTT ; oral glucose toler

刊名：Metabolism

出版年：2015

7.N-glucosides as human sodium-dependent glucose cotransporter 2 (hSGLT2) inhibitors

作者：Yasuo Yamamoto ; Eiji Kawanishi ; Yuichi Koga ; Shigeki Sakamaki ; Toshiaki Sakamoto ; Kiichiro Ueta ; Yasuaki Matsushita ; Chiaki Kuriyama ; Minoru Tsuda-Tsukimoto ; Sumihiro Nomura

关键词：SGLT2 ; Sodium-dependent glucose cotransporter ; Diabetes ; Glucoside ; N-glucoside

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：2013

8.Effects of LX4211, a Dual Sodium-Dependent Glucose Cotransporters 1 and 2 Inhibitor, on Postprandial Glucose, Insulin, Glucagon-like Peptide 1, and Peptide Tyrosine Tyrosine in a Dose-Timing Study in Healthy Subjects

作者：Brian Zambrowicz ; Ike Ogbaa ; Kenny Frazier ; Phillip Banks ; Anne Turnage ; Joel Freiman ; Kristi A. Boehm ; Dennis Ruff ; David Powell ; Arthur Ss

关键词：Diabetes ; GLP-1 ; SGLT1 ; SGLT2 ; PYY ; urinary glucose excretion

刊名：Clinical Therapeutics

出版年：2013

9.Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter

作者：Rolf Grempler^a ; ¹ ; ^{rolf.grempler@boehringer-ingelheim.com} ; Robert Augustin^a ; ¹ ; Stefanie Froehner^d ; ¹ ; Tobias Hildebrandt^b ; Eric Simon^b ; Michael Mark^a ; Peter Eickelmann^c

关键词：AMG ; ¦Á-methyl-d-glucose ; EST ; expressed sequence tag ; GLUT ; glucose transporter ; HEK ; human embryonal kidney ; hSGLT ; human sodium-dependent glucose transporter ; IC50 ; half maximal inhibitory concentration ; NGS ; next generation sequencing

刊名：FEBS Letters

出版年：2012

10.C-Glucosides with heteroaryl thiophene as novel sodium-dependent glucose cotransporter 2 inhibitors

作者：Yuichi Koga ; Shigeki Sakamaki ; Mitsuya Hongu ; Eiji Kawanishi ; Toshiaki Sakamoto ; Yasuo Yamamoto ; Hirotaka Kimata ; Keiko Nakayama ; Chiaki Kuriyama ; Yasuaki Matsushita ; Kiichiro Ueta ; Minoru Tsuda-Tsukimoto ; Sumihiro Nomura

关键词：Type 2 diabetes ; SGLT2 inhibitor ; Thiophene ; Glucoside ; Canagliflozin

刊名：Bioorganic and Medicinal Chemistry

出版年：2013

按检索点细分(39)

题名(4)

关键词(8)

文摘(26)

按出版年细分(39)

2016年(5)

2015年(1)

2013年(3)

2012年(4)

2011年(3)

2009年(2)

2008年(1)

2007年(1)

2006年(3)

2002年(1)

2001年(1)

2000年(1)

2000年及以前(13)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700