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在“Elsevier电子期刊”中，命中：145条，耗时：小于0.01 秒

在所有数据库中总计命中：176条

1.Shape-based virtual screening, synthesis and evaluation of novel pyrrolone derivatives as antiviral agents against HCV

作者：Marcella Bassetto^a ; ^{bassettom@cardiff.ac.uk} ; Pieter Leyssen^b ; Johan Neyts^b ; Mark M. Yerukhimovich^c ; David N. Frick^c ; Andrea Brancale^a

关键词：Ligand-based virtual screening ; Shape-similarity search ; Novel pyrrolones ; Anti-HCV activity

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase

作者：Marcella Bassetto^a ; ^{bassettom@cardiff.ac.uk} ; Pieter Leyssen^b ; Johan Neyts^b ; Mark M. Yerukhimovich^c ; David N. Frick^c ; Matthew Courtney-Smith^a ; Andrea Brancale^a

关键词：Structure-based virtual screening ; HCV NS3-helicase ; Piperazine derivatives ; Anti-HCV activity ; NS3 helicase inhibitors

刊名：European Journal of Medicinal Chemistry

出版年：2017

3.Computer-aided identification, synthesis and evaluation of substituted thienopyrimidines as novel inhibitors of HCV replication

作者：Marcella Bassetto^a ; ^{bassettom@cardiff.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Pieter Leyssen^b ; Johan Neyts^b ; Mark M. Yerukhimovich^c ; David N. Frick^c ; Andrea Brancale^a

关键词：Structure-based virtual screening ; Substituted thieno-pyrimidines ; Anti-HCV activity

刊名：European Journal of Medicinal Chemistry

出版年：2016

4.Silencing of hepatitis C virus replication by a non-viral vector based on solid lipid nanoparticles containing a shRNA targeted to the internal ribosome entry site (IRES)

关键词：Hepatitis C ; Solid lipid nanoparticles ; RNAi ; shRNA ; Hyaluronic acid ; HCV-IRES

刊名：Colloids and Surfaces B: Biointerfaces

出版年：2016

5.Assessment of the activity of directly acting antivirals and other products against different genotypes of hepatitis C virus prevalent in resource-poor countries

作者：Hayat Khan^a ; ^b ; Jan Paeshuyse^a ; Sheeba Murad^b ; Johan Neyts^a ; ^{johan.neyts@rega.kuleuven.be" class="auth_mail" title="E-mail the corresponding author}

关键词：Hepatitis C virus ; Direct acting antivirals ; Food additives ; Subgenomic replicons

刊名：Antiviral Research

出版年：2016

6.Soraphen A: A broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity

作者：George Koutsoudakis¹ ; ^# ; Iné ; s Romero-Brey² ; ^&dagger ; ; Carola Berger² ; ^&dagger ; ; Gemma Pé ; rez-Vilaró ; ¹ ; Paula Monteiro Perin³ ; ⁴ ; Florian Wolfgang Rudolf Vondran⁴ ; ⁵ ; Markus Kalesse⁶ ; Kirsten Harmrolfs⁷ ; Rolf Mü ; ller⁷ ; Javier P. Martinez⁸ ; Thomas Pietschmann³ ; ⁴ ; Ralf Bartenschlager² ; ⁹ ; Mark Brö ; nstrup⁶ ; Andreas Meyerhans⁸ ; ¹⁰ ; Juana Dí ; ez¹ ; ^{juana.diez@upf.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：HCV ; hepatitis C virus ; HIV ; human immunodeficiency virus ; VLDL ; very low density lipoprotein ; LDL ; low density lipoprotein ; ACC ; acetyl-CoA carboxylase ; SorA ; Soraphen A ; DMVs ; double membrane vesicles ; HCVcc ; cell culture-derived HCV ; TOFA ; 5-(tetradecyloxy)-2-furoic acid ; MOI ; multiplicity of infection ; EC50 ; half maximal effective concentration ; CC50 ; half maximal cytotoxic concentration ; SI ; selectivity index ; 2&prime ; -C-Met ; 2&prime ; -C-methyladenosine ; PHHs ; primary human hepatocytes ; TCID

刊名：Journal of Hepatology

出版年：2015

7.Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors

作者：Guanghai Jin^a ; ¹ ; Sungjin Lee^a ; ¹ ; Moonju Choi^a ; Seohyun Son^a ; Geon-Woo Kim^b ; Jong-Won Oh^b ; Choongho Lee^a ; ^{choongholee@dongguk.edu" class="auth_mail} ; Kyeong Lee^a ; ^{kaylee@dongguk.edu" class="auth_mail}

关键词：Hepatitis C virus (HCV) ; Chemical genetics ; HCV replication inhibitors ; Indole derivatives ; Structure&ndash ; activity relationship (SAR) study ; NS5B RNA polymerase inhibitor

刊名：European Journal of Medicinal Chemistry

出版年：21 March, 2014

8.Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a

作者：Helen Kylefjord ; Axel Danielsson ; Susanne Sedig ; Oscar Belda ; Daniel Wiktelius ; Lotta Vrang ; Paul Targett-Adams

关键词：Hepatitis C virus ; Genotype 3 ; Replicon ; NS5A ; NS5B ; chimera

刊名：Journal of Virological Methods

出版年：January, 2014

9.HCV transmission by hepatic exosomes establishes a productive infection

作者：Fran莽ois-Lo茂c Cosset ; Marl猫ne Dreux

关键词：HCV ; hepatitis C virus ; MVB ; multivesicular body ; pDC ; plasmacytoid dendritic cells ; SGR ; subgenomic replicon

刊名：Journal of Hepatology

出版年：March, 2014

10.Retinoids and rexinoids inhibit hepatitis C virus independently of retinoid receptor signaling

作者：Yuko Murakami ; Masayoshi Fukasawa ; Yukihiro Kaneko ; Tetsuro Suzuki ; Takaji Wakita ; Hidesuke Fukazawa

关键词：Hepatitis C virus ; HCV ; Retinoid ; Retinoic acid ; Rexinoid

刊名：Microbes and Infection

出版年：February, 2014

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