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在“Elsevier电子期刊”中，命中：1,127条，耗时：0.0289609 秒

在所有数据库中总计命中：1,441条

1.Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A₃ and A_2A subtypes

作者：Daniela Poli^a ; Matteo Falsini^a ; Flavia Varano^a ; Marco Betti^a ; Katia Varani^b ; Fabrizio Vincenzi^b ; Anna Maria Pugliese^c ; Felicita Pedata^c ; Diego Dal Ben^d ; Ajiroghene Thomas^d ; Ilaria Palchetti^e ; ^f ; Francesca Bettazzi^e ; Daniela Catarzi^a ; ^{daniela.catarzi@unifi.it} ; Vittoria Colotta^a

关键词：G protein-coupled receptors ; Adenosine receptor antagonists ; Imidazopyrazines ; Bicyclic heteroaromatic systems ; Ligand-receptor modeling studies

刊名：European Journal of Medicinal Chemistry

出版年：2017

2.Expression of muscarinic acetylcholine receptors in hepatocytes from rat fibrotic liver

作者：Lin Luo^a ; ^b ; ^{luolin@ntu.edu.cn} ; Tingting Xu^a ; ¹ ; Pengbo Wang^c ; Liuliu Mao^a ; Chenghao Xi^a ; Jinhua Huang^a ; Wei Zhang^a ; ^b ; ^{zwei_601@126.com}

关键词：Ach ; acetylcholine ; ALB ; albumin ; ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; CCl4 ; carbon tetrachloride ; DMEM ; Dulbecco&rsquo ; s modified Eagle medium ; ECM ; extracellular matrix ; FHCs ; hepatocytes from fibrotic liver ; GSH ; glutathione ; HCs ; hepatocytes ; HF ; hepatic fibrosis ; HSCs ; hepatic stellate cells ; Hyp ; hydroxyproline ; mAchRs ; muscarinic acetylcholine receptors ; MMPs ; matrix metalloproteinases ; Pi ; nitrate pilocarpine ; TIMPs ; tissue inhibitors of metalloproteinases ; RT-

刊名：Experimental and Toxicologic Pathology

出版年：2017

3.Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines as α₁-adrenergic receptor antagonist with uro-selective activity

作者：Aleksandra Rak^a ; Vittorio Canale^b ; Krzysztof Marciniec^c ; Paweł Żmudzki^b ; Magdalena Kotańska^a ; Joanna Knutelska^a ; Agata Siwek^e ; Gabriela Stachowicz^e ; Marek Bednarski^a ; ^{marek.bednarski@uj.edu.pl" class="auth_mail" title="E-mail the corresponding author} ; Leszek Nowiński^d ; Małgorzata Zygmunt^a ; Paweł Zajdel^b ; Jacek Sapa^a

关键词：LCAP flexible biomimetic ; Arylsulfonamide derivatives of pyrrolidines and piperidines ; α1-Adrenoceptors antagonists ; α1A/B receptor selectivity ; Uroselective activity ; Benign prostatic hyperplasia

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.Design, synthesis, crystal structure, biological evaluation and molecular docking studies of carbazole-arylpiperazine derivatives

作者：Wei Xu^a ; ^&dagger ; ; Junjun Huang^b ; ^&dagger ; ; Binhao Shao^b ; Xingjie Xu^b ; Renwang Jiang^a ; ^{rwjiang2008@126.com" class="auth_mail" title="E-mail the corresponding author} ; Mu Yuan^b ; ^{mryuanmu838@sina.com" class="auth_mail" title="E-mail the corresponding author}

关键词：α1-Adrenoceptor antagonists ; Arylpiperazine ; X-ray crystallography ; Molecular docking ; Pharmacophore model

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

5.Characterization of PCS1055, a novel muscarinic M₄ receptor antagonist

作者：Carrie H. Croy^b ; Wai Y. Chan^a ; ¹ ; Andrea M. Castetter^b ; Marla L. Watt^b ; ² ; Anne T. Quets^b ; Christian C. Felder^b ; ^{Felder@lilly.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Muscarinic M4 receptors ; Competitive antagonists ; PCS1055 ; Subtype selectivity

刊名：European Journal of Pharmacology

出版年：2016

6.The adrenergic α₂-receptor, sexual incentive motivation and copulatory behavior in the male rat

作者：Xi Chu ; Anders Å ; gmo ; ^{andersa@psyk.uit.no" class="auth_mail" title="E-mail the corresponding author}

关键词：Sexual behavior ; Incentive motivation ; Ambulatory activity ; α2 antagonists ; α2 agonists

刊名：Pharmacology Biochemistry and Behavior

出版年：2016

7.Equilibrium and kinetic selectivity profiling on the human adenosine receptors

作者：Dong Guo¹ ; Gabrielle S. Dijksteel ; Tirsa van Duijl ; Maxime Heezen ; Laura H. Heitman ; Adriaan P. IJzerman ; ^{ijzerman@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：ARs ; adenosine receptors ; CGS15943 ; 9-chloro-2-(2-furanyl)-[12 ; 4]triazolo [1 ; 5-c]quinazolin-5-amine ; CHAPS ; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate ; CPA ; N6-cyclopentyladenosine ; DPCPX ; 1 ; 3-dipropyl-8-cyclopentylxanthine ; IB-MECA ; N6-(3-Iodobenzyl)adenosine-5&prime ; -N-methyluronamide ; GPCR ; G protein-coupled receptor ; k1 ; the association rate constant of the radioligand ; k2 ; the dissociation rate constant of the radioligand ; k3 ; the association rate constant of the unlabeled l

刊名：Biochemical Pharmacology

出版年：2016

8.Toward PET imaging of A_2B adenosine receptors: a carbon-11 labeled triazinobenzimidazole tracer: Synthesis and imaging of a new A2B PET tracer

作者：Debora Petroni^a ; Chiara Giacomelli^b ; Sabrina Taliani^b ; ^{sabrina.taliani@farm.unipi.it" class="auth_mail" title="E-mail the corresponding author} ; Elisabetta Barresi^b ; Marco Robello^b ; Simona Daniele^b ; Antonietta Bartoli^c ; Silvia Burchielli^d ; Silvia Pardini^a ; Piero A. Salvadori^a ; Federico Da Settimo^b ; Claudia Martini^b ; Maria Letizia Trincavelli^b ; ^{maria.trincavelli@farm.unipi.it" class="auth_mail" title="E-mail the corresponding author} ; Luca Menichetti^a ; ^d

关键词：A2B adenosine receptors ; carbon-11 ; PET ; radiotracer ; substituted-[12 ; 4]triazino[4 ; 3-a]benzimidazoles

刊名：Nuclear Medicine and Biology

出版年：2016

9.Opioid system mediated anti-nociceptive effect of agomelatine in mice

作者：Merve Kasap^a ; Ö ; zgü ; r Devrim Can^b ; ^{ozgurdt@anadolu.edu.tr" class="auth_mail" title="E-mail the corresponding author}

关键词：Agomelatine ; Opioid receptor ; Hot-plate test ; Tail-clip test ; Acetic acid-induced writhing test

刊名：Life Sciences

出版年：2016

10.New therapeutic opportunities for 5-HT_2C receptor ligands in neuropsychiatric disorders

作者：Giuseppe Di Giovanni^a ; ^b ; ^{giuseppe.digiovanni@um.edu.mt" class="auth_mail" title="E-mail the corresponding author} ; Philippe De Deurwaerdè ; re^c ; ^{deurwaer@u-bordeaux2.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：5-HT receptors ; mRNA editing ; G protein coupled receptors ; Receptor oligomers ; Dopamine ; GABA

刊名：Pharmacology and Therapeutics

出版年：2016

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