搜索页_ TGF-β-activated kinase 1

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1.Analysis of the expression of the Wnt family of proteins and its modulatory role on cytokine expression in non activated and activated astroglial cells

作者：Pau Gonzalez ; ^{paug@sescam.jccm.es} ; Francisco Javier Rodrí ; guez ; ^{fjrodriguez@sescam.jccm.es}

关键词：CNS ; central nervous system ; BBB ; blood brain barrier ; Fz ; Frizzled ; ROR ; receptor tyrosine kinase-like orphan receptor ; PTK7 ; protein tyrosine kinase 7 ; PCP ; planar cell polarity ; Wif ; Wnt inhibitory factor ; Dkk ; Dickkopf ; sFRP ; secreted Frizzled-related protein ; Rspo ; R-spondin ; NA ; non-activated ; SC ; lesioned spinal cord extract ; cm ; centimeter ; GFAP ; glial fibrillary acidic protein ; LPS ; lipopolysaccharide ; hpa ; hours post-activation ; RT ; room temperature ; BSA ; bovine serum albumin ; qRT-PCR

刊名：Neuroscience Research

出版年：2017

2.C/EBP homologous protein promotes NSAID-activated gene 1-linked pro-inflammatory signals and enterocyte invasion by enteropathogenic Escherichia coli

作者：Seong-Hwan Park^a ; ¹ ; Mira Yu^a ; ¹ ; Juil Kim^a ; Yuseok Moon^a ; ^b ; ^moon@pnu.edu

关键词：Enteropathogenic Escherichia coli (EPEC) ; C/EBP homologous protein (CHOP) ; Nuclear factor kappa B (NF-κB) ; NSAID-activated gene 1 (NAG-1)

刊名：Microbes and Infection

出版年：2017

3.Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle

作者：Gabriel L. Galea ; PhD^a ; ¹ ; Lee B. Meakin ; PhD^a ; ¹ ; ^{lee.meakin@bristol.ac.uk} ; Marie A. Harris ; PhD^b ; Peter J. Delisser ; BVSc(Hons)^a ; Lance E. Lanyon ; DSc^a ; Stephen E. Harris ; PhD^b ; Joanna S. Price ; PhD^a

关键词：MAPK ; mitogen-activated protein kinase ; Actn2 ; actinin alpha 2 ; AMPK ; adenosine monophosphate-activated protein kinase ; Atf3 ; activating transcription factor 3 ; ATP ; Adenosine triphosphate ; b2MG ; Beta-2-microglobulin ; Bcl11a ; B-cell CLL/lymphoma 11A ; Bcl212 ; Bcl-2-like protein 2 ; BiNGO ; A Biological Network Gene Ontology tool ; BMD ; bone mineral density ; BMP ; bone morphogenetic protein ; Ccna2 ; cyclin A2 ; Ccnd3 ; cyclin D3 ; Cdc20 ; cell division cycle 20 ; Cdca3 ; cell division cycle associated 3 ; Cdk

刊名：Gene

出版年：2017

4.Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells

作者：Zhiquan Chen^a ; ¹ ; Xi Xie^b ; ^c ; ¹ ; ^{xiaprilxie@berkeley.edu} ; ^{xiexi@hainu.edu.cn} ; Junying Huang^a ; Wenyan Gong^a ; Xiaoyu Zhu^c ; Qiuhong Chen^a ; Jiani Huang^a ; Heqing Huang^a ; ^{huangheq@mail.sysu.edu.cn}

关键词：AGEs ; advanced glycation end products ; ARE ; anti-oxidant response element ; Cx43 ; connexin43 ; DN ; diabetic nephropathy ; ECM ; extracellular matrix ; EMSA ; electrophoretic mobility shift assay ; FN ; fibronectin ; GMCs ; glomerular messangial cells ; GJIC ; Gap junctional intercellular communication ; HO-1 ; heme oxygenase 1 ; ICAM-1 ; intercellular adhesion molecule-1 ; Keap1 ; kelch like ECH associated protein 1 ; MAPK ; mitogen-activated protein kinase ; Nrf2 ; nuclear factor E2-related factor 2 ; PKC ; protein ki

刊名：Free Radical Biology and Medicine

出版年：2017

5.Regulation of merlin by protein phosphatase 1-TIMAP and EBP50 in endothelial cells

作者：Anita Boratkó ; ¹ ; Margit Pé ; ter¹ ; Csilla Csortos ; ^{csortos@med.unideb.hu}

关键词：BPAEC ; Bovine Pulmonary Artery Endothelial Cells ; ERM ; ezrin ; radixin ; moesin ; FERM ; band 4.1 ; ezrin ; radixin ; moesin ; GST ; glutathione S-transferase ; ILK ; integrin-linked kinase ; IP ; immunoprecipitation ; MYPT ; myosin phosphatase target subunit ; NF2 ; neurofibromatosis type 2 ; NHERF ; Na+/H+ exchanger regulatory factor ; PAK ; p21-activated kinase ; PKA ; cAMP-dependent protein kinase ; PKC ; protein kinase C ; PP ; protein phosphatase ; PP1c ; catalytic subunit of PP1 ; PP1c-MYPT1 ; myosin phosphatase ; TIMAP

刊名：The International Journal of Biochemistry & Cell Biology

出版年：2017

6.Blockade of TGF-β-activated kinase 1 prevents advanced glycation end products-induced inflammatory response in macrophages

作者：Xingxin Xu ; Xiangming Qi ; Yunxia Shao ; Yuanyuan Li ; Xin Fu ; Shiyao Feng ; Yonggui Wu ; ^{wuyonggui@medmail.com.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：AGEs ; advanced glycation end products ; DN ; diabetic nephropathy ; TAK1 ; TGF-β-activated kinase 1 ; BMMs ; bone marrow-derived macrophages ; MAPKs ; mitogen-activated protein kinases ; NF-κB ; nuclear factor kappa B protein ; MCP-1 ; monocyte chemo-attractant protein-1 ; TNF-α ; tumor necrosis factor-alpha ; IL-1β ; interleukin-1 beta ; MAP3K7 ; mitogen-activated protein kinase kinase kinase 7 ; BMP ; bone morphogenetic protein ; TABs ; TAK1-binding proteins.

刊名：Cytokine

出版年：2016

7.BIX02189 inhibits TGF-β1-induced lung cancer cell metastasis by directly targeting TGF-β type I receptor

作者：Seong Ji Park^a ; Yu Sun Choi^a ; Seungkoo Lee^b ; Young Jae Lee^c ; Suntaek Hong^c ; Sanghwa Han^a ; Byung-Chul Kim^a ; ^{bckim@kangwon.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：BLI ; bioluminescent imaging ; EGF ; epidermal growth factor ; EMT ; epithelial-to-mesenchymal transition ; ERK ; extracellular-signal-regulated kinase ; Fluc ; firefly luciferase ; MAPK ; mitogen-activated protein kinase ; MEK5 ; mitogen-activated protein kinase/extracellular-signal-regulated kinase5 ; MMP ; matrix metalloproteinase ; PBS ; phosphate buffered saline ; siRNA ; small interfering RNA ; TβRI ; transforming growth factor-β1 receptor type I ; TGF-β1 ; transforming growth factor-β1

刊名：Cancer Letters

出版年：2016

8.Mangiferin protect myocardial insults through modulation of MAPK/TGF-β pathways

作者：Kapil Suchal^a ; ¹ ; Salma Malik^a ; ¹ ; Nanda Gamad^a ; Rajiv Kumar Malhotra^a ; Sameer N. Goyal^b ; Shreesh Ojha^c ; Santosh Kumari^d ; Jagriti Bhatia^a ; Dharamvir Singh Arya^a ; ^{dsarya16@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：CAT ; catalase ; DAP ; diastolic arterial pressure ; ERK1/2 ; extracellular regulated kinase 1/2 ; GSH ; reduced glutathione ; IL-6 ; interleukin-6 ; IR ; ischemia-reperfusion ; JNK ; c-Jun NH2 terminal kinase ; MNG ; mangiferin ; LVEDP ; left ventricular end diastolic pressure ; ± ; LVdP/dt ; rate of change of pressure development ; MAP ; mean arterial pressure ; MAPK ; mitogen activated protein kinase ; MDA ; malondialdehyde ; SAP ; systolic arterial pressure ; SOD ; superoxide dismutase ; TGF-β ; transforming growth fa

刊名：European Journal of Pharmacology

出版年：2016

9.The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage

作者：Xingxin Xu ; Zhe Fan¹ ; Xiangming Qi ; Yunxia Shao ; Yonggui Wu ; ^{wuyonggui@medmail.com.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：TAK1 ; MAPK ; NF-κB ; Diabetic nephropathy ; Inflammation

刊名：International Immunopharmacology

出版年：2016

10.Arecoline-induced pro-fibrotic proteins in LLC-PK1 cells are dependent on c-Jun N-terminal kinase

作者：Sheng-Hsuan Lin^a ; ¹ ; Shean-Jaw Chiou^b ; ¹ ; Wan-Ting Ho^b ; Chao-Tang Chuang^a ; Lea-Yea Chuang^b ; ^{chuangly@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jinn-Yuh Guh^c ; ^d ; ^{guhjy@kmu.edu.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：CKD ; chronic kidney disease ; TGF-β ; transforming growth factor-β ; JNK ; c-Jun N-terminal kinase ; PAI1 ; plasminogen activator inhibitor-1 ; COX2 ; cyclooxygenase 2 ; AN ; areca nut ; ERK ; extracellular signal-regulated kinase ; DMSO ; dimethylsulfoxide ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyl tetrazolium Bromide ; SEM ; standard errors of the mean

刊名：Toxicology

出版年：2016

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