搜索页_+Toxicological+assessments

常用资源

电子图书

期刊论文

学位会议

外文资源

特色专题

内部出版物

Wiley电子期刊(5)	ProQuest学位论文(1)	Elsevier电子期刊(386)
SpringerLink电子期刊(64)	NATURE电子期刊(1)	ACS电子期刊(20)

在“Elsevier电子期刊”中，命中：386条，耗时：小于0.01 秒

在所有数据库中总计命中：477条

1.EEG in non-clinical drug safety assessments: Current and emerging considerations

作者：Simon Authier^a ; ^{authiers@ca.citoxlab.com" class="auth_mail" title="E-mail the corresponding author} ; Marcus S. Delatte^b ; Mary-Jeanne Kallman^c ; Joanne Stevens^d ; Carrie Markgraf^e

关键词：EEG ; Seizure ; Polysomnography ; Safety pharmacology ; Convulsion ; Neurotoxicity ; Sleep ; Spike ; Telemetry

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

2.Chemistry, manufacturing and exposure assessments to support generally recognized as safe (GRAS) determinations

作者：Leila Barraj ; Mary Murphy ; Nga Tran ; Barbara Petersen ; ^{bpetersen@exponent.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Exposure assessment ; GRAS determination methods

刊名：Regulatory Toxicology and Pharmacology

出版年：2016

3.Cardiovascular safety assessments in the cynomolgus monkey: Unmasking potential background arrhythmias in general toxicity studies

作者：Andrea Greiter-Wilke^a ; ^{andrea.greiter-wilke@roche.com" class="auth_mail" title="E-mail the corresponding author} ; Ted Baird^b ; Kyle O'Donohue^b ; Annette Koerner^a

关键词：Atrioventricular block ; Jacketed ECG ; Toxicity study ; Mauritian cynomolgus monkey ; Methods

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

4.Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review

关键词：Methodological quality ; Reporting quality ; Risk of bias ; Scoping review ; Toxicity studies

刊名：Environment International

出版年：2016

5.The effects of housing conditions on baseline cardiovascular parameters and the sensitivity to detect changes in contractility in telemetry-implanted dogs

作者：Nataliya Sadekova ; ^{nataliya.sadekova@crl.com" class="auth_mail" title="E-mail the corresponding author} ; Ghislaine Boudreau ; Benoit Jalbert ; Kevin Norton

关键词：Beagle dog ; Contractility ; Left ventricular pressure ; Methods ; Social housing ; Telemetry

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

6.Functional neurotoxicity evaluation of noribogaine using video-EEG in cynomolgus monkeys

作者：Simon Authier^a ; ^b ; ^{authiers@ca.citoxlab.com" class="auth_mail" title="E-mail the corresponding author} ; Michael V. Accardi^a ; Dominique Paquette^c ; Mylè ; ne Pouliot^a ; Joseph Arezzo^d ; ^e ; R. John Stubbs^f ; Ronald J. Gerson^g ; Lawrence T. Friedhoff^h ; Holger Weisⁱ

关键词：Noribogaine ; Electroencephalography ; EEG ; Cynomolgus monkey ; Pentylenetetrazol

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

7.Risk assessment of down-the-drain chemicals at large spatial scales: Model development and application to contaminants originating from urban areas in the Saint Lawrence River Basin

作者：Gü ; nther Grill^a ; ^{guenther.grill@mail.mcgill.ca" class="auth_mail" title="E-mail the corresponding author} ; Usman Khan^b ; Bernhard Lehner^a ; Jim Nicell^b ; Joseph Ariwi^a

关键词：Pharmaceuticals ; Down-the-drain chemicals ; Geo-spatial modeling ; Risk assessment ; Wastewater ; Large spatial scales

刊名：Science of the Total Environment

出版年：2016

8.Cross-laboratory analytical validation of the cardiac biomarker NT-proANP in rat

作者：Petra Vinken^a ; ^{pvinken@its.jnj.com" class="auth_mail" title="E-mail the corresponding author} ; William J. Reagan^b ; Luis A. Rodriguez^c ; Wayne R. Buck^d ; Jie Lai-Zhang^d ; Nick Goeminne^a ; Gaby Barbacci^b ; Ray Liu^e ; Nicholas M.P. King^g ; Steven K. Engle^f ; Heidi Colton^c

关键词：Rat ; Cardiac hypertrophy ; Safety biomarker ; Toxicity ; Validation ; NT-proANP ; Natriuretic peptides

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

9.The standardized functional observational battery: Its intrinsic value remains in the instrument of measure: The rat

作者：David V. Gauvin^a ; ^{david.gauvin@mpiresearch.com" class="auth_mail" title="E-mail the corresponding author} ; Joshua D. Yoder^a ; David L. Holdsworth^b ; Marci L. Harter^b ; Jonelle R. May^b ; Noelle Cotey^b ; Jill A. Dalton^b ; Theodore J. Baird^c

关键词：Functional observational battery ; FOB ; Rat ; Functional changes ; Behavior analysis ; Ethology ; Strain differences ; Phylogeny ; Gender ; Age ; Circadian rhythms

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

10.Applying probabilistic ‘weight-of-evidence’ assessments to diverse safety endpoints

作者：Derek Leishman

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

按检索点细分(386)

题名(12)

关键词(3)

文摘(168)

按出版年细分(386)

2027年及以后(11)

2016年(16)

2015年(9)

2013年(12)

2012年(15)

2011年(20)

2010年(15)

2009年(12)

2008年(21)

2007年(157)

2006年(8)

2005年(9)

2004年(13)

2003年(5)

2002年(11)

2001年(9)

2000年(4)

2000年及以前(39)

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700