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1.The substrate binding domains of human SIAH E3 ubiquitin ligases are now crystal clear

作者：Qi Zhang^a ; Zhongduo Wang^b ; Feng Hou^a ; Rachel Harding^a ; Xinyi Huang^c ; Aiping Dong^a ; John R. Walker^a ; Yufeng Tong^a ; ^c ; ^{yufeng.tong@utoronto.ca}

关键词：DUB ; Deubiquitinase ; ERAD ; endoplasmic-reticulum associated degradation ; ESI ; electrospray ionization ; HEPES ; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid ; ITC ; isothermal titration calorimetry ; ML ; maximum-likelihood ; RING ; really-interesting new genes ; SBD ; substrate binding domain ; SIAH ; seven in absentia homolog ; Tagg ; temperature of aggregation ; TCEP ; tris(2-carboxyethyl)phosphine ; TEV ; tobacco etch virus ; USP ; ubiquitin-specific protease ; ZnF ; zinc finger

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

2.Regulation of T helper cell differentiation by E3 ubiquitin ligases and deubiquitinating enzymes

作者：Si-Fa Gao^a ; Bo Zhong^b ; Dandan Lin^a ; ^{lindandan@whu.edu.cn}

关键词：Deubiquitinating enzymes ; E3 ubiquitin ligases ; T helper cell differentiation

刊名：International Immunopharmacology

出版年：2017

3.Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells

作者：Jeanne G. Quirit^a ; ^{jgquirit@berkeley.edu} ; Sergey N. Lavrenov^b ; ^{satory@mail.ru} ; Kevin Poindexter^a ; ^{kpoindexter25@gmail.com} ; Janice Xu^a ; ^{jamicexu@scripps.edu} ; Christine Kyauk^a ; ^{ckyauk@berkeley.edu} ; Kathleen A. Durkin^c ; ^{durkin@berkeley.edu} ; Ida Aronchik^a ; ^{idaaronchik@gmail.com} ; Thomas Tomasiak^d ; ^{tomasiak@msg.ucsf.edu} ; Yaroslav A. Solomatin^b ; ^{hercules44@yandex.ru} ; Maria N. Preobrazhenskaya^b ; ^{satory@mail.ru} ; Gary L. Firestone^a ; ^{glfire@berkeley.edu}

关键词：Indole-3-carbinol analogues ; Ligand-target protein interactions ; NEDD4-1 ubiquitin ligase ; In silico computational modeling ; Anti-cancer compounds ; Melanoma cells

刊名：Biochemical Pharmacology

出版年：2017

4.Emerging Mechanisms in Initiating and Terminating Autophagy

作者：Manuela Antonioli¹ ; ² ; Martina Di Rienzo¹ ; ³ ; Mauro Piacentini¹ ; ³ ; Gian Maria Fimia¹ ; ⁴ ; ^{gianmaria.fimia@inmi.it}

关键词：ULK1 ; BECLIN-1 ; AMBRA1 ; TRAF6 ; TRIM ; CULLIN ; Exocyst ; IRGM.

刊名：Trends in Biochemical Sciences

出版年：2017

5.Dynamics and Assembly of ASB-Containing E3 Ubiquitin Ligases

刊名：Biophysical Journal

出版年：2017

6.E3 ubiquitin ligases as novel targets for inflammatory diseases

作者：Santosh Kumar Goru ; Anuradha Pandey ; Anil Bhanudas Gaikwad ; ^{anil.gaikwad@pilani.bits-pilani.ac.in" class="auth_mail" title="E-mail the corresponding author}

关键词：HECT ; homologous to the E6AP carboxyl terminus ; RING ; really interesting new gene ; UPS ; ubiquitin proteasome system ; TNFα ; tumour necrosis factor-α ; MCP-1 ; monocyte chemotactic protein-1 ; CCR2 ; CC chemokine receptor type 2 ; TLR4 ; toll-like receptor 4 ; GM-CSF ; granulocyte-macrophage colony-stimulating factor ; VCAM-1 ; vascular cell adhesion molecule-1 ; Ang II ; Angiotensin II ; HFD ; high fat diet ; CHIP ; carboxyl terminus of heat shock protein 70-interacting protein ; ICAM-1 ; intercellular adhesion m

刊名：Pharmacological Research

出版年：2016

7.Cullin 5-RING E3 ubiquitin ligases, new therapeutic targets?

作者：Isabelle Lamsoul^a ; ^b ; Sandrine Uttenweiler-Joseph^a ; ^b ; Christel Moog-Lutz^a ; ^b ; Pierre G. Lutz^a ; ^b ; ^{Pierre.Lutz@ipbs.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：E3 ubiquitin ligase ; Cullin RING ligase ; Ubiquitin-proteasome system ; Therapeutic targets

刊名：Biochimie

出版年：2016

8.The role of E3 ubiquitin-ligases MuRF-1 and MAFbx in loss of skeletal muscle mass

作者：Oren Rom ; ^{orenrom@tx.technion.ac.il" class="auth_mail" title="E-mail the corresponding author} ; Abraham Z. Reznick

关键词：4E BP ; eukaryotic translation initiation factor-4E-binding protein ; Akt ; protein kinase B ; BCAA ; branched-chain amino acids ; CKD ; chronic kidney disease ; CLA ; conjugated linoleic acids ; COPD ; chronic obstructive pulmonary disease ; CS ; cigarette smoke ; CSA ; cross-sectional area ; DHA ; docosahexaenoic acid ; E1 ; ubiquitin-activating enzyme ; E2 ; ubiquitin-conjugating enzyme ; E3 ; ubiquitin-ligase enzyme ; eIF3-f ; eukaryotic translation initiation factor 3-subunit F ; EPA ; eicosapentaenoic acid ; ERK ; ext

刊名：Free Radical Biology and Medicine

出版年：2016

9.Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis

作者：Jinho Heo^a ; Rebeka Eki^a ; ^b ; Tarek Abbas^a ; ^b ; ^c ; ^{ta8e@virginia.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：F-box ; SCF ; Ubiquitin ; E3 ubiquitin ligases ; Cancer

刊名：Seminars in Cancer Biology

出版年：2016

10.Types of Ubiquitin Ligases

作者：Francesca Ester Morreale¹ ; Helen Walden¹

刊名：Cell

出版年：2016

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