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1.The Atypical Ubiquitin E2 Conjugase UBE2L3 Is an Indirect Caspase-1 Target and Controls IL-1β Secretion by Inflammasomes

作者：Matthew J.G. Eldridge¹ ; Julia Sanchez-Garrido¹ ; Gil Ferreira Hoben¹ ; Philippa J. Goddard¹ ; Avinash R. Shenoy¹ ; ² ; ^{a.shenoy@imperial.ac.uk}

关键词：inflammasomes ; caspase-1 ; IL-1β ; UBE2L3 ; ubiquitin ; proteasome ; caspase-4 ; Salmonella ; Listeria ; commensals

刊名：Cell Reports

出版年：2017

2.Effects of in vitro and in vivo avermectin exposure on alpha synuclein expression and proteasomal activity in pigeons

作者：Ming Li^a ; ^b ; Shuo Zhou^a ; Xian-Song Wang^a ; Ci Liu^a ; Shu Li^a ; ^{lishu@neau.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：AVM ; avermectin ; AVMs ; avermectins ; α-Syn ; alpha synuclein ; NAC ; non-amyloid-β-component ; AD ; Alzheimer disease ; NACP ; non-amyloid-β-component precursor ; PD ; Parkinson's disease ; MSA ; multiple system atrophy ; DLB ; Dementia with Lewy bodies ; UPP ; ubiquitin proteasome pathway ; E1 ; ubiquitin activating enzyme ; E2s ; ubiquitin transferase ; E3s ; ubiquitin ligase ; DUBs ; deubiquitinating enzymes ; DMSO ; dimethyl sulfoxide ; LC50 ; lethal concentration 50 ; qPCR ; quantitative real-time PCR ; PBS ; phosphate-b

刊名：Ecotoxicology and Environmental Safety

出版年：2017

3.Ubiquitin-specific protease 21 regulating the K48-linked polyubiquitination of NANOG

作者：Seul-Ki Kwon¹ ; Da-Hye Lee¹ ; Soo-Yeon Kim ; Jung-Hyun Park ; Jihye Choi ; Kwang-Hyun Baek ; ^{baek@cha.ac.kr}

关键词：Deubiquitination ; Differentiation ; Pluripotency ; Proteasomal degradation ; Ubiquitination ; Stem cell

刊名：Biochemical and Biophysical Research Communications

出版年：2017

4.Prolyl oligopeptidase inhibition attenuates the toxicity of a proteasomal inhibitor, lactacystin, in the alpha-synuclein overexpressing cell culture

关键词：aSyn ; alpha-synuclein ; [A53T]aSyn ; cell lines stably overexpressing human A53T mutated form of aSyn ; [A30P]aSyn ; cell lines stably overexpressing human A30P mutated form of aSyn ; HMW ; high-molecular-weight ; LC3BI-II ; microtubule-associated protein light chain 3B I-II ; NC ; negative control ; OD ; optical density ; PD ; Parkinson&rsquo ; s disease ; PREP ; prolyl oligopeptidase ; UPS ; ubiquitin-proteasome system ; WB ; Western blot ; Wt ; Wild type

刊名：Neuroscience Letters

出版年：2017

5.Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in the human Quinone Oxidoreductase 1 (NQO1)

作者：Hidam Bishworjit Singh ^{hidam_bishworjit@yahoo.com} ; Dristi Deka ^{dristideka628@gmail.com} ; Dhiramani Das ^{dhiramanidas@rocketmail.com} ; Debasish Borbora ; ^{Debasish.borbora@gauhati.ac.in}

关键词：SNP ; Single nucleotide polymorphisms ; nsSNPs ; Non-synonymous SNPs ; NQO1 ; NAD(P)H Quinone Oxidoreductase 1 ; SIFT ; Sorting Intolerant from Tolerant ; PolyPhen ; phenotype polymorphism ; ROVEAN ; Protein Variation Effect Analyzer ; PDB ; Protein Data Bank ; GDT ; global distance test ; uGDT ; un-normalized GDT ; RMSD ; root mean squared deviation ; QMEAN ; Qualitative Model Energy Analysis ; ProSA ; Protein Structure Analysis ; UCSF ; University of California ; San Francisco

刊名：Meta Gene

出版年：2017

6.The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5

作者：Huan-Tian Zhang^a ; ^b ; Ling-Fei Zeng^b ; ^c ; Qing-Yu He^d ; W. Andy Tao^b ; ^c ; Zhen-Gang Zha^a ; ^{zhzgg@vip.163.com" class="auth_mail" title="E-mail the corresponding author} ; Chang-Deng Hu^b ; ^{hu1@purdue.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：PRMT5 ; protein arginine methyltransferase 5 ; EGFR ; epidermal growth factor receptor ; TNF ; tumor necrosis factor ; NF-Y ; nuclear factor Y ; PKC ; protein kinase C ; Hsp90 ; heat shock protein 90 ; UPS ; ubiquitin&ndash ; proteasome system ; CHIP ; carboxyl terminus of heat shock cognate 70-interacting protein ; TPR ; tetratricopeptide repeat ; Hsp70 ; heat shock protein 70 ; HEK293T ; human embryonic kidney 293 T ; CHX ; cycloheximide ; PMA ; phorbol-12-myristate-13-acetate ; GA ; geldanamycin ; 17-AAG ; 17-(Allylam

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

7.Hepatitis C virus core protein inhibits E6AP expression via DNA methylation to escape from ubiquitin-dependent proteasomal degradation

作者：Juri Kwak¹ ; Joo Hee Shim¹ ; Indira Tiwari ; Kyung Lib Jang ; ^{kljang@pusan.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：Core protein ; DNA methylation ; E6-associated protein ; Hepatitis C virus ; Ubiquitin-proteasome system

刊名：Cancer Letters

出版年：2016

8.Proteasomal degradation of damaged polyubiquitin

作者：Tomonao Inobe ; ^{inobe@ctg.u-toyama.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Miyuki Nozaki

关键词：Ubiquitin ; Proteasome ; Protein degradation ; Autophagy

刊名：Biochemical and Biophysical Research Communications

出版年：2016

9.The long N-terminus of the human monocarboxylate transporter 8 is a target of ubiquitin-dependent proteasomal degradation which regulates protein expression and oligomerization capacity

关键词：MCT8 ; N-terminus ; Ubiquitination ; Degradation ; Oligomerization

刊名：Molecular and Cellular Endocrinology

出版年：2016

10.Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation

作者：Laura A. Jaenicke¹ ; ⁵ ; Bjö ; rn von Eyss¹ ; ⁵ ; Anne Carstensen¹ ; Elmar Wolf¹ ; Wenshan Xu² ; Ann Katrin Greifenberg³ ; Matthias Geyer³ ; Martin Eilers¹ ; ² ; ⁶ ; ^{martin.eilers@biozentrum.uni-wuerzburg.de" class="auth_mail" title="E-mail the corresponding author} ; Nikita Popov² ; ⁴ ; ⁶ ; ^{nikita.popov@biozentrum.uni-wuerzburg.de" class="auth_mail" title="E-mail the corresponding author}

关键词：MYC ; ubiquitin ; proteasomal degradation ; PAF1C ; transcriptional elongation ; RNA polymerase

刊名：Molecular Cell

出版年：2016

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