搜索页_+Wiskott-Aldrich+syndrome

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1.Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions

作者：Clara Lubeseder-Martellato^a ; ^{clara.lubeseder-martellato@tum.de} ; Katharina Alexandrow^a ; Ana Hidalgo-Sastre^a ; Irina Heid^b ; Sophie Luise Boos^a ; ^c ; Thomas Briel^a ; Roland M. Schmid^a ; ^c ; Jens T. Siveke^a ; ^c ; ^d ; ^{j.siveke@dkfz.de}

关键词：Oncogenic KRas ; Fluid-phase endocytosis ; Pancreatic ductal adenocarcinoma (PDAC) ; Acinar-to-ductal metaplasia (ADM) ; Acinar epithelial explants ; Neural-Wiskott-Aldrich syndrome protein (N-WASP) ; Mice models

刊名：EBioMedicine

出版年：2017

2.Structural Basis of Arp2/3 Complex Inhibition by GMF, Coronin, and Arpin

作者：Olga S. Sokolova¹ ; Angelina Chemeris¹ ; ⁵ ; Siyang Guo² ; Salvatore L. Alioto² ; Meghal Gandhi² ; Shae Padrick³ ; Evgeniya Pechnikova⁴ ; Violaine David⁵ ; Alexis Gautreau⁵ ; Bruce L. Goode² ; ^{goode@brandeis.edu}

关键词：Arp ; actin-related protein ; NPF ; nucleation-promoting factor ; GFP ; green fluorescent protein ; GMF ; glia maturation factor ; EM ; electron microscopy ; GST ; glutathione S-transferase ; FSC ; Fourier shell correlation ; TEV ; tobacco etch virus ; VCA ; verproline central acidic ; WASP ; Wiskott Aldrich syndrome protein ; WAVE ; WASP family verproline-homologous

刊名：Journal of Molecular Biology

出版年：2017

3.50 Years Ago in The Journal of Pediatrics: Wiskott-Aldrich Syndrome: Clinical, Immunologic, and Pathologic Observations

作者：Emily B. Heikamp ; MD ; PhD ; MSc

刊名：The Journal of Pediatrics

出版年：2017

4.WIP promotes in-vitro invasion ability, anchorage independent growth and EMT progression of A549 lung adenocarcinoma cells by regulating RhoA levels

作者：Amrita Salvi ; Thirumaran Thanabalu ; ^{thirumaran@ntu.edu.sg}

关键词：WIP ; Actin cytoskeleton ; TGF-β1 induced EMT ; RhoA

刊名：Biochemical and Biophysical Research Communications

出版年：2017

5.Novel WASP mutation in a patient with Wiskott-Aldrich syndrome: Case report and review of the literature

作者：M. Eghbali^a ; M. Sadeghi-Shabestari^b ; F. Najmi Varzaneh^c ; ^d ; A. Zare Bidoki^c ; N. Rezaei^a ; ^c ; ^d ; ^{rezaei_nima@tums.ac.ir" class="auth_mail" title="E-mail the corresponding author}

关键词：Eczema ; Recurrent infection ; Thrombocytopenia ; Novel mutation ; Wiskott&ndash ; Aldrich syndrome

刊名：Allergologia et Immunopathologia

出版年：2016

6.Gene Correction of iPSCs from a Wiskott-Aldrich Syndrome Patient Normalizes the Lymphoid Developmental and Functional Defects

作者：Tamara J. Laskowski¹ ; ⁸ ; Yasmine Van Caeneghem² ; ⁸ ; Rasoul Pourebrahim¹ ; Chao Ma³ ; Zhenya Ni³ ; Zita Garate¹ ; ⁴ ; ⁵ ; Ana M. Crane¹ ; Xuan Shirley Li¹ ; Wei Liao¹ ; Manuel Gonzalez-Garay⁶ ; Jose Carlos Segovia⁴ ; ⁵ ; David E. Paschon⁷ ; Edward J. Rebar⁷ ; Michael C. Holmes⁷ ; Dan Kaufman³ ; ⁹ ; Bart Vandekerckhove² ; Brian R. Davis¹ ; ^{brian.r.davis@uth.tmc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：induced pluripotent stem cells ; genome editing ; immune deficiency ; T cells

刊名：Stem Cell Reports

出版年：2016

7.B-cell reconstitution after lentiviral vector-mediated gene therapy in patients with Wiskott-Aldrich syndrome

作者：Maria Carmina Castiello ; PhD^a ; Samantha Scaramuzza ; PhD^a ; Francesca Pala ; MS^a ; Francesca Ferrua ; MD^b ; Paolo Uva ; PhD^c ; Immacolata Brigida ; PhD^a ; Lucia Sereni ; MS^a ; Mirjam van der Burg ; PhD^d ; Giorgio Ottaviano ; MD^b ; Michael H. Albert ; MD^e ; Maria Grazia Roncarolo ; MD^a ; ^f ; Luigi Naldini ; MD ; PhD^a ; ^f ; Alessandro Aiuti ; MD ; PhD^a ; ^g ; Anna Villa ; MD^a ; ^h ; ^{villa.anna@hsr.it" class="auth_mail" title="E-mail the corresponding author} ; Marita Bosticardo ; PhD^a

关键词：Wiskott-Aldrich syndrome ; gene therapy ; B cell ; primary immunodeficiency ; lentiviral vector

刊名：Journal of Allergy and Clinical Immunology

出版年：2015

8.Antipsychotic drugs induce cell cytoskeleton reorganization in glial and neuronal cells via Rho/Cdc42 signal pathway

作者：Mao-Liang Chen^a ; ^{cater0656@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Fu-Ming Tsai^a ; ^b ; Ming-Cheng Lee^a ; Yi-Yin Lin^a

关键词：APDs ; antipsychotic drugs ; ARP2/3 ; actin-related protein 2/3 ; Cdc42 ; cell division control protein 42 homolog ; CNS ; central nervous system ; p-JNK ; c-Jun. N-terminal kinase ; MLC2 ; myosin light chain 2 ; N-WASP ; neural Wiskott&ndash ; Aldrich syndrome protein ; p-MLC2 ; phospho-myosin light chain 2 ; PAK1 ; serine/threonine protein kinase ; PFN1 ; profilin 1 ; Rac ; Ras-related C3 botulinum toxin substrate ; RhoA ; Ras homolog gene family ; member A ; RhoGDI1 ; Rho GDP-dissociation inhibitor 1 ; ROCK1 ; Rho-associa

刊名：Progress in Neuropsychopharmacology & Biological Psychiatry

出版年：2016

9.Local treatment for scleritis secondary to Wiskott-Aldrich syndrome

作者：M. Randon^a ; J.-M. Michot^b ; O. Lambotte^b ; M. Labetoulle^a ; A. Rousseau^a ; ^{antoine.rousseau@bct.aphp.fr" class="auth_mail" title="E-mail the corresponding author}

刊名：Journal Français d'Ophtalmologie

出版年：2016

10.Wiskott-Aldrich Syndrome in a Two-Month-Old Boy Presenting with Intussusception and Normal-Sized Platelets

作者：Vanessa L. Bundy ; MD ; PhD ; FAAP¹ ; Maria Garcia-Lloret ; MD ; FAAAAI²

刊名：Journal of Allergy and Clinical Immunology

出版年：2016

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