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Elsevier电子期刊(217)

在“Elsevier电子期刊”中，命中：217条，耗时：0.067968 秒

在所有数据库中总计命中：264条

1.A triple exon-skipping luciferase reporter assay identifies a new CLK inhibitor pharmacophore

作者：Yihui Shi ; Jaehyeon Park ; Chandraiah Lagisetti ; Wei Zhou ; Lidia C. Sambucetti ; Thomas R. Webb ; ^{thomas.webb@sri.com}

关键词：CLK ; cdc2-like kinase ; MDM2 ; mouse double minute 2 homolog ; Luc ; luciferase ; TEA ; triethylamine ; DIPEA ; diisopropylethylamine ; EtOAc ; ethyl acetate

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle

作者：Gabriel L. Galea ; PhD^a ; ¹ ; Lee B. Meakin ; PhD^a ; ¹ ; ^{lee.meakin@bristol.ac.uk} ; Marie A. Harris ; PhD^b ; Peter J. Delisser ; BVSc(Hons)^a ; Lance E. Lanyon ; DSc^a ; Stephen E. Harris ; PhD^b ; Joanna S. Price ; PhD^a

关键词：MAPK ; mitogen-activated protein kinase ; Actn2 ; actinin alpha 2 ; AMPK ; adenosine monophosphate-activated protein kinase ; Atf3 ; activating transcription factor 3 ; ATP ; Adenosine triphosphate ; b2MG ; Beta-2-microglobulin ; Bcl11a ; B-cell CLL/lymphoma 11A ; Bcl212 ; Bcl-2-like protein 2 ; BiNGO ; A Biological Network Gene Ontology tool ; BMD ; bone mineral density ; BMP ; bone morphogenetic protein ; Ccna2 ; cyclin A2 ; Ccnd3 ; cyclin D3 ; Cdc20 ; cell division cycle 20 ; Cdca3 ; cell division cycle associated 3 ; Cdk

刊名：Gene

出版年：2017

3.Further investigation of Paprotrain: Towards the conception of selective and multi-targeted CNS kinase inhibitors

作者：Christophe Labriè ; re^a ; ¹ ; ^{christophe.labriere@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Olivier Lozach^b ; ² ; Mé ; lina Blairvacq^b ; ³ ; Laurent Meijer^c ; Catherine Guillou^a ; ^{catherine.guillou@cnrs.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Alzheimer's disease ; DYRKs ; Cdc2-like kinases ; Paprotrain ; Photochemistry ; 11H-pyridocarbazole ; Multi-targeted ; Dual & selective inhibitors

刊名：European Journal of Medicinal Chemistry

出版年：2016

4.Genome-wide investigation of schizophrenia associated plasma Ndel1 enzyme activity

作者：Ary Gadelha^a ; ^{aryararipe@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author} ; ^{aryararipe@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jonathan Coleman^b ; Gerome Breen^b ; ^h ; Diego Robles Mazzoti^c ; Camila M. Yonamine^a ; ^d ; Renata Pellegrino^e ; Vanessa Kiyomi Ota^a ; ^f ; Sintia Iole Belangero^a ; ^f ; Joseph Glessner^e ; Patrick Sleiman^e ; ^g ; Hakon Hakonarson^e ; ^g ; Mirian A.F. Hayashi^d ; ¹ ; ^{mhayashi@unifesp.br" class="auth_mail" title="E-mail the corresponding author} ; ^{mhayashi@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Rodrigo A. Bressan^a ; ¹

关键词：SCZ ; schizophrenia ; HCs ; health controls ; GWAS ; Genome-Wide Association Studies ; Ndel1 ; Nuclear Distribution Element-Like 1 ; DISC1 ; Disrupted in Schizophrenia-1 ; SCID ; Structured clinical interview of DSM IV ; SNP ; Single Nucleotide Polymorphism ; BMI ; Body Mass Index ; CAMK1D ; Calcium/calmodulin-dependent protein kinase 1D ; MAGI2 ; Membrane-Associated Guanylate Kinase ; WW and PDZ Domains-Containing 2 ; GABRG3 ; Gamma-Aminobutyric Acid Receptor ; Gamma-3 ; CCDC25 ; Coiled-Coil Domain Containing Protein 2

刊名：Schizophrenia Research

出版年：2016

5.PKC-alpha modulation by miR-483-3p in platinum-resistant ovarian carcinoma cells

关键词：API5 ; apoptosis inhibitor 5 ; ARF1 ; ADP ribosylation factor 3 ; BCA ; bicinchoninic acid ; BBC3/PUMA ; BCL2 binding component 3 ; BIRC5 ; baculoviral IAP (inhibitor of apoptosis) repeat containing 5 ; CDC25A ; cell division cycle 25A ; CDK4 ; cyclin-dependent kinase 4 ; CDK6 ; cyclin-dependent kinase 6 ; Chk1 ; checkpoint kinase 1 ; FACS ; Fluorescence-activated cell sorting ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; GO ; Gene Ontology ; IGF2 ; insulin-like growth factor 2 ; miRNA ; microRNA ; MRP2 ; ABC transpo

刊名：Toxicology and Applied Pharmacology

出版年：2016

6.5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms

作者：Oliver C.F. Orban^a ; ^&dagger ; ; Ricarda S. Korn^a ; ^&dagger ; ; Diego Bení ; tez^b ; Andrea Medeiros^b ; ^c ; Lutz Preu^a ; Nadè ; ge Loaë ; c^d ; Laurent Meijer^d ; Oliver Koch^e ; Marcelo A. Comini^b ; ^{mcomini@pasteur.edu.uy" class="auth_mail" title="E-mail the corresponding author} ; Conrad Kunick^a ; ^f ; ^{c.kunick@tu-braunschweig.de" class="auth_mail" title="E-mail the corresponding author}

关键词：ACN ; acetonitrile ; CDK ; cyclin-dependent kinase ; CLK ; cdc2-like kinase ; CK ; casein kinase ; DIPEA ; diisopropylethylamine ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; DMF ; N ; N-dimethylformamide ; DMSO ; dimethyl sulfoxide ; DYRK1A ; dual specificity tyrosine phosphorylation-regulated protein kinase 1A ; DTT ; dithiothreitol ; EDTA ; ethylenediaminetetraacetic acid ; EGTA ; ethylene glycol-bis(β-aminoethyl ether)-NN ; N&prime ; N&prime ; -tetraacetic acid ; FCS ; fetal calf serum ; FSC ; forward scatter ; G

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

7.Synthesis and biological evaluation of heteroaryl styryl sulfone derivatives as anticancer agents

作者：Yi Long ; Mingfeng Yu ; Peng Li ; Saiful Islam ; Aik Wye Goh ; Malika Kumarasiri ; Shudong Wang ; ^{shudong.wang@unisa.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Kinase inhibitor ; Polo-like kinase 1 ; Ras-driven signaling pathways ; Non-ATP competitive inhibition ; Anti-cancer agents

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Leucettine L41, a DYRK1A-preferential DYRKs/CLKs inhibitor, prevents memory impairments and neurotoxicity induced by oligomeric Aβ_25-35 peptide administration in mice

作者：Gaë ; lle Naert^a ; ^b ; Valentine Ferré ; ^a ; Johann Meunier^a ; ^b ; Emeline Keller^a ; ^b ; Susanna Malmströ ; m^a ; ^b ; Laurent Givalois^a ; Franç ; ois Carreaux^c ; Jean-Pierre Bazureau^c ; Tangui Maurice^a ; ^b ; ^{maurice@univ-montp2.fr" class="auth_mail" title="E-mail the corresponding author}

关键词：Kinase ; DYRK1A ; Leucettines ; Aβ25&ndash ; 35 ; Amyloid toxicity ; Tau phosphorylation

刊名：European Neuropsychopharmacology

出版年：2015

9.APC/C^Cdh1-dependent degradation of Cdc20 requires a phosphorylation on CRY-box by Polo-like kinase-1 during somatic cell cycle

作者：Sun-Yi Hyun¹ ; Badmaarag Sarantuya¹ ; Hee-Jae Lee ; Young-Joo Jang ; ^{yjjang@dankook.ac.kr}

关键词：Cdc20 ; Degron ; CRY box ; APC/CCdh1 ; Plk1 ; Phosphorylation

刊名：Biochemical and Biophysical Research Communications

出版年：2013

10.Overexpression of polo-like kinase 1 and its clinical significance in human non-small cell lung cancer

作者：Zhao-Xia Wang^a ; ; ¹ ; ; ^{wangzhaox@yahoo.com.cn} ; Dong Xue^b ; ; ¹ ; Zhi-Li Liu^a ; Bin-Bin Lu^a ; Hai-Bo Bian^a ; Xuan Pan^a ; Yong-Mei Yin^c ; ; ^{yinyongmei_nanjing@yahoo.com.cn}

关键词：Polo-like kinase 1 ; Non-small cell lung cancer ; Immunohistochemistry ; Prognosis ; RNA interference ; Apoptosis ; Chemotherapy ; Radiotherapy

刊名：The International Journal of Biochemistry and Cell Biology

出版年：2012

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