搜索页_ extracellular signal regulated kinase1/2

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Elsevier电子期刊(120)

在“Elsevier电子期刊”中，命中：120条，耗时：0.016992 秒

在所有数据库中总计命中：162条

1.Anesthetics inhibit extracellular signal-regulated Kinase1/2 phosphorylation via NMDA receptor, phospholipase C and protein kinase C in mouse hippocampal slices

作者：Gao Haiying^a ; Han Mingjie^a ; Zhang Lingyu^a ; Wang Qingxiang^a ; Wang Haisong^a ; Zhang Bingxi^b ; ^{zbxtryy@126.com}

关键词：Anesthetics ; Extracellular signal-regulated Kinase1/2 ; Phosphorylation ; Hippocampus ; Phospholipase C ; Protein kinase C

刊名：Neurochemistry International

出版年：2017

2.Discovery and structure activity relationship study of novel indazole amide inhibitors for extracellular signal-regulated kinase1/2 (ERK1/2)

作者：Lei Li^a ; ^&dagger ; ; Feifei Liu^b ; ^&dagger ; ; Nan Jin^b ; Shuai Tang^b ; Zhuxi Chen^a ; ^b ; Xiaotong Yang^b ; Jian Ding^b ; Meiyu Geng^b ; Lei Jiang^a ; Min Huang^b ; ; Jianhua Cao^a ;

关键词：ERK1/2 kinase inhibitor ; Indazole amide ; Structure based drug design

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.14-3-3η is a novel growth-promoting and angiogenic factor in hepatocellular carcinoma

作者：Jian Shen¹ ; ^&dagger ; ; Fei Jiang² ; ^&dagger ; ; Ye Yang² ; ^&dagger ; ; Guangming Huang³ ; ^&dagger ; ; Fuxing Pu³ ; ^&dagger ; ; Qinqiang Liu¹ ; ^&dagger ; ; Lijun Chen² ; Liang Ju¹ ; Ming Lu¹ ; Fei Zhou¹ ; Chi Zhang¹ ; Xiagang Luo¹ ; Xiaojun Yang¹ ; Chengyu Jiao⁴ ; Xiangcheng Li⁴ ; Zhong Li² ; Yuan Li² ; ^{liyuan@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Jianping Zhang¹ ; ^{zjpnjmu@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Cxcl1 ; C-X-C motif-ligand 1 ; ECs ; endothelial cells ; EMT ; epithelial to mesenchymal transition ; ERK ; extracellular signal-regulated kinase ; FAK ; focal adhesion kinase ; FRA-1 ; fos related antigen 1 ; NK-κB ; nuclear factor kappa B ; PCNA ; proliferating cell nuclear antigen ; TGF-β ; transforming growth factor beta ; TUNEL ; transferase-mediated deoxyuridine triphosphate-biotin nick end labeling ; VEGF ; vascular endothelial growth factor ; Zeb-1 ; zinc finger E-box-binding protein-1

刊名：Journal of Hepatology

出版年：2016

4.Leptin induces the generation of procoagulant, tissue factor bearing microparticles by human peripheral blood mononuclear cells

作者：Silvia Petrini^a ; Tommaso Neri^a ; Stefania Lombardi^b ; Cinzia Cordazzo^a ; ¹ ; Cristina Balì ; a^a ; Valentina Scalise^a ; Pierluigi Paggiaro^a ; Roberto Pedrinelli^a ; Alessandro Celi^a ; ^{alessandro.celi@med.unipi.it" class="auth_mail" title="E-mail the corresponding author}

关键词：MP ; microparticles ; TF ; tissue factor ; PBMC ; peripheral blood mononuclear cells ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)- 2 ; 5-diphenyltetrazolium bromide ; PS ; phosphatidylserine ; FITC ; fluoresceinisothyocianate ; PE ; phycoerythrin ; SSc ; side scatter ; FSc ; forward scatter ; PBS ; phosphate buffered saline ; MAPK ; mitogen activated protein kinases ; ERK ; extracellular signal-regulated kinase ; JNK ; c-Jun N-terminal kinase ; PLC ; phospholipase C ; CFSE ; carboxyfluoresceinsuccinimidyl ester ; [Ca2+]i ; intracellula

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2016

5.Dynamic monitoring of GPER-mediated estrogenic effects in breast cancer associated fibroblasts: An alternative role of estrogen in mammary carcinoma development

作者：Haojun Luo^a ; Manran Liu^b ; Shujuan Luo^c ; Tenghua Yu^d ; Chengyi Wu^d ; Guanglun Yang^d ; Gang Tu^d ; ^{tugang68@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：α-SMA ; α-smooth muscle actin ; CAF ; cancer associated fibroblast ; Ca2+ ; calcium ; E2 ; 17-β-estradiol ; ECM ; extracellular matrix ; EC50 ; concentration for 50% of maximal effect ; EGFR ; epidermal growth factor receptor ; ER ; estrogen receptor ; ERK ; extracellular signal-regulated kinase ; FAP ; fibroblast active protein ; FBS ; fetal bovine serum ; G1 ; 1-(4-(6-Bromobenzo[1 ; 3]dioxol-5-yl)-3a45 ; 9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl)-ethanone ; 1-[(3aS ; 4R ; 9bR-rel)-4-(6-bromo-1 ; 3-benzodioxol-5-yl)-3a459

刊名：Steroids

出版年：2016

6.MicroRNA-204 suppresses epileptiform discharges through regulating TrkB-ERK1/2-CREB signaling in cultured hippocampal neurons

作者：Lei Xiang^a ; ^b ; Yanping Ren^b ; Xun Li^b ; Wen Zhao^c ; ^{zhaowen2@yahoo.cn" class="auth_mail" title="E-mail the corresponding author} ; Yijun Song^b ; ^{songyj@tmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：miR ; microRNA ; TrkB ; tropomyosin related kinase type B ; SE ; status epilepticus ; PLCγ1 ; phospholipase Cγ1 ; ERK1/2 ; extracellular signal-regulated kinase1/2 ; CREB ; cAMP response-element binding protein ; TLE ; temporal lobe epilepsy ; MTLE ; mesial temporal lobe epilepsy ; BDNF ; brain-derived neurotrophic factor ; CNS ; central nervous system ; PI3K ; phosphoinositide-3-kinase ; MAPK ; mitogen-activated protein kinase ; DIV ; days in vitro ; GFP ; green fluorescent protein ; NC ; negative control siRNA ; MOI ; multi

刊名：Brain Research

出版年：2016

7.Activation of classical estrogen receptor subtypes reduces tight junction disruption of brain endothelial cells under ischemia/reperfusion injury

作者：Jin A. Shin^a ; ^b ; Joo Chun Yoon^b ; ^c ; Minsuk Kim^a ; Eun-Mi Park^a ; ^b ; ^{empark@ewha.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：BBB ; Blood&ndash ; brain barrier ; DMSO ; dimethyl sulfoxide ; DPN ; 2 ; 3-bis(4-hydroxy-phenyl)-propionitrile ; ERK1/2 ; extracellular signal-regulated kinase1/2 ; E2 ; 17β-estradiol 3-benzoate ; ERs ; estrogen receptors ; HIF-1α ; hypoxia-inducible factor 1α ; FITC ; fluorescein isothiocyanate ; H2DCF-DA ; 2&prime ; 7&prime ; -dichlorodihydrofluorescein diacetate ; LDH ; lactate dehydrogenase ; MCAO ; middle cerebral artery occlusion ; MTT ; 3-[4 ; 5-dimethylthiazol-2-yl]-2 ; 5-diphenyl tetrazolium bromide ; OD ; optical densit

刊名：Free Radical Biology and Medicine

出版年：2016

8.ROS-JNK1/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis

作者：Zili Zhang^a ; Mei Guo^b ; Shifeng Zhao^a ; Jiangjuan Shao^c ; Shizhong Zheng^a ; ^d ; ^{nytws@163.com}

关键词：ALT ; alanine aminotransferase ; AST ; aspartate aminotransferase ; ALP ; alkaline phosphatase ; Atg ; autophagy-related gene ; α-SMA ; alpha smooth muscle actin ; Cat ; catalase ; DHA ; dihydroartemisinin ; ERK1/2 ; extracellular regulated kinase1/2 ; GSH ; glutathione ; GSSG ; glutathione disulfide ; HSCs ; hepatic stellate cells ; IFN-γ ; Interferon-γ ; IL ; Interleukin ; JNK ; c-Jun N-terminal kinase ; LC3 ; microtubule-associated protein 1 light chain 3 ; MAPK ; mitogen activated protein kinases ; MitoPY1 ; Mito Peroxy Yel

刊名：Free Radical Biology and Medicine

出版年：2016

9.Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling

作者：Juanli Fu ; Qiong Shi ; Xiufang Song ; Xiaomin Xia ; Chuanyang Su ; Zixuan Liu ; Erqun Song ; Yang Song ; ^{songyangwenrong@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; ^{ysong@swu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：COX-2 ; cyclooxygenase-2 ; ELISA ; enzyme-linked immunosorbent assay ; EMSA ; electrophoretic mobility shift assay ; ERK1/2 ; extracellular regulated kinase1/2 ; HCB ; hexachlorobenzene ; IκBα ; inhibitor of NF-κB ; IKK ; inhibitor of nuclear factor kappa-B kinase ; IL-1β ; interleukin-1beta ; IL-6 ; interleukin-6 ; iNOS ; inducible nitric oxide synthase ; JNK ; c-Jun N-terminal kinase ; MAPK ; mitogen-activated protein kinases ; NAC ; N-acetyl-l-cysteine ; NF-κB ; nuclear factor-kappa B ; NO ; nitric oxide ; PCP ; pentachlor

刊名：Environmental Toxicology and Pharmacology

出版年：2016

10.Optogenetic activation of striatal cholinergic interneurons regulates L-dopa-induced dyskinesias

作者：Tanuja Bordia¹ ; Xiomara A. Perez¹ ; Jaime E. Heiss ; Danhui Zhang ; Maryka Quik ; ^{maryka.quik@sri.com" class="auth_mail" title="E-mail the corresponding author}

关键词：AAV ; adeno-associated virus ; ACh ; acetylcholine ; AIMs ; abnormal involuntary movements ; ANOVA ; analysis of variance ; LIDs ; L-dopa-induced dyskinesias ; ChAT ; choline acetyltransferase ; ChR2 ; channel rhodopsin 2 ; DAT ; dopamine transporter ; ERK ; extracellular signal regulated kinase1/2 ; mAChR ; muscarinic acetylcholine receptor ; nAChR ; nicotinic acetylcholine receptor ; 6-OHDA ; 6-hydroxydopamine

刊名：Neurobiology of Disease

出版年：2016

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